Search Results - "Leão, Felipe B."

Nanomineralogy in the real world: A perspective on nanoparticles in the environmental impacts of coal fire by Sehn, Janaína L., de Leão, Felipe B., da Boit, Kátia, Oliveira, Marcos L.S., Hidalgo, Gelsa E., Sampaio, Carlos H., Silva, Luis F.O.

“…Detailed geochemistry similarities between the burning coal cleaning rejects (BCCRs) and non-anthropogenic geological environments are outlined here. While no…”
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The mobilization of hazardous elements after a tropical storm event in a polluted estuary by Rodriguez-Iruretagoiena, Azibar, de Vallejuelo, Silvia Fdez- Ortiz, de Diego, Alberto, de Leão, Felipe B., de Medeiros, Diego, Oliveira, Marcos L.S., Tafarel, Silvio R., Arana, Gorka, Madariaga, Juan Manuel, Silva, Luis F.O.

“…The Tubarão River (Santa Catarina, Brazil) is affected by hazardous elements (HEs) pollution from abandoned coal mines, agricultural activities, urban…”
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Study of environmental pollution and mineralogical characterization of sediment rivers from Brazilian coal mining acid drainage by Silva, Luis F.O., Fdez- Ortiz de Vallejuelo, Silvia, Martinez-Arkarazo, Irantzu, Castro, Kepa, Oliveira, Marcos L.S., Sampaio, Carlos H., de Brum, Irineu A.S., de Leão, Felipe B., Taffarel, Silvio R., Madariaga, Juan M.

“…Acid drainage from coal mines and metal mining is a major source of underground and surface water contamination in the world. The coal mining acid drainage…”
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Are children playgrounds safe play areas? Inorganic analysis and lead isotope ratios for contamination assessment in recreational (Brazilian) parks by Gredilla, Ainara, Fdez-Ortiz de Vallejuelo, Silvia, Gomez-Nubla, Leticia, Carrero, Jose Antonio, de Leão, Felipe B., Madariaga, Juan Manuel, Silva, Luis F. O.

“…In city playgrounds, there is a potential risk of harming children’s health by contamination coming from anthropogenic activities. With the aim to determinate…”
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Toll-like Receptor (TLR)-induced Rasgef1b expression in macrophages is regulated by NF-κB through its proximal promoter by Leão, Felipe B., Vaughn, Lauren S., Bhatt, Dev, Liao, Will, Maloney, Dillon, Carvalho, Brener C., Oliveira, Leonardo, Ghosh, Sankar, Silva, Aristóbolo M.

“…•Immune response-related elements are present in the 5′ flanking sequence of Rasgef1b.•Minimal TLR-responsive promoter region harbors Sp1 and NF-κB binding…”
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Transcriptomic analysis reveals that RasGEF1b deletion alters basal and LPS-induced expression of genes involved in chemotaxis and cytokine responses in macrophages by Fernandes, Heliana B., de Oliveira, Isadora Mafra, Postler, Thomas S., Lima, Sérgio Q., Santos, Cícera A. C., Oliveira, Michaelle S., Leão, Felipe B., Ghosh, Sankar, Souza, Maria C., Andrade, Warrison, Silva, Aristóbolo M.

“…Ras guanine nucleotide exchange factor member 1b (RasGEF1b) of the RasGEF/CDC25 domain-containing family is preferentially expressed by macrophages. However,…”
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Both knock-down and overexpression of Rap2a small GTPase in macrophages result in impairment of NF-κB activity and inflammatory gene expression by Carvalho, Brener C., Oliveira, Leonardo C., Rocha, Carolina D., Fernandes, Heliana B., Oliveira, Isadora M., Leão, Felipe B., Valverde, Thalita M., Rego, Igor M.G., Ghosh, Sankar, Silva, Aristóbolo M.

“…•Rap2a GTPase is activated by LPS in macrophages.•RasGEF1b directly activates Rap2a, but it is only partially required for the GTPase activation after LPS…”
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Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry by Zamudio, Roxana, Pereira, Latife, Rocha, Carolina D., Berg, Douglas E., Muniz-Queiroz, Thaís, Sant Anna, Hanaisa P., Cabrera, Lilia, Combe, Juan M., Herrera, Phabiola, Jahuira, Martha H., Leão, Felipe B., Lyon, Fernanda, Prado, William A., Rodrigues, Maíra R., Rodrigues-Soares, Fernanda, Santolalla, Meddly L., Zolini, Camila, Silva, Aristóbolo M., Gilman, Robert H., Tarazona-Santos, Eduardo, Kehdy, Fernanda S. G.

“…Background Gastric adenocarcinoma is associated with chronic infection by Helicobacter pylori and with the host inflammatory response triggered by it, with…”
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Data in support of Rap2a GTPase expression, activation and effects in LPS-mediated innate immune response and NF-κB activation by Carvalho, Brener C., Oliveira, Leonardo C., Rocha, Carolina D., Fernandes, Heliana B., Oliveira, Isadora M., Leãõ, Felipe B., Valverde, Thalita M., Rego, Igor M.G., Ghosh, Sankar, Silva, Aristóbolo M.

“…We present here the data to support the understanding of the implication of Rap2a GTPase in LPS-induced innate immune response and NF-κB activation. The data…”
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