Search Results - "Leão, A.C"

Deacidification of organic liquid products by fractional distillation in laboratory and pilot scales by Ferreira, C.C., Costa, E.C., de Castro, D.A.R., Pereira, M.S., Mâncio, A.A., Santos, M.C., Lhamas, D.E.L., da Mota, S.A.P., Leão, A.C, Duvoisin, S., Araújo, M.E., Borges, Luiz E.P., Machado, N.T.

“…•De-acidification of OLP investigated by distillation in laboratory and pilot scales.•The effect of column height and reflux on the properties of distillation…”
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Studies on the dynamic resolution of Crizotinib intermediate by de França, Alexandre da S., Silva, Marcus V.M., Neves, Rebeca V., de Souza, Stefania P., Leão, Raquel A.C., Monteiro, Carlos M., Rocha, Ângelo, Afonso, Carlos A.M., de Souza, Rodrigo O.M.A.

“…[Display omitted] Crizotinib is an anti-cancer agent approved for treatment of non-small cell lung carcinoma. Retrosynthetic analysis revels…”
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Cannabidiol Discovery and Synthesis—a Target‐Oriented Analysis in Drug Production Processes by Aguillón, Anderson R., Leão, Raquel A. C., Miranda, Leandro S. M., Souza, Rodrigo O. M. A.

“…The current state of evidence and recommendations for cannabidiol (CBD) and its health effects change the legal landscape and aim to destigmatize its…”
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New Palladacycle-Derived Acylhydrazones as Pre-catalysts in Mirozoki-Heck Coupling and Oxyarylations by Leão, Raquel A C, Pinho, Vagner D, Coelho, Artur S, Kümmerle, Arthur E, Costa, Paulo R R

“…New acylhydrazone-based palladacycles are prepared and evaluated as pre-catalysts in Mirozoki-Heck and oxyarylation reactions…”
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Immobilization of lipase B from Candida antarctica on epoxy‐functionalized silica: characterization and improving biocatalytic parameters by de Souza, Stefânia P, de Almeida, Rayza AD, Garcia, Gabriel G, Leão, Raquel AC, Bassut, Jonathan, de Souza, Rodrigo OMA, Itabaiana, Ivaldo

“…BACKGROUND In this work, lipase B from Candida antarctica (CaLB) was immobilized on Purolite® ECR8205F, Purolite® ECR8214F and Immobead® IB150 P epoxy resins…”
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A brief history behind the most used local anesthetics by Bezerra, Marco M., Leão, Raquel A.C., Miranda, Leandro S.M., de Souza, Rodrigo O.M.A.

“…The chemistry behind the discovery of local anesthetics is a beautiful way of understanding the development and improvement of medicinal/organic chemistry…”
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Process Intensification for Obtaining a Cannabidiol Intermediate by Photo-oxygenation of Limonene under Continuous-Flow Conditions by Aguillón, Anderson R., Leão, Raquel A. C., de Oliveira, Kleber Thiago, Brocksom, Timothy John, Miranda, Leandro S. M., de Souza, Rodrigo O. M. A.

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Two-step continuous flow synthesis of α-terpineol by de Carvalho, Beatriz L.C., Aguillon, Anderson R., Leão, Raquel A.C., de Souza, Rodrigo O.M.A.

“…α-Terpineol is a naturally occurring monoterpene present in essential oils, of high value on the market as it is widely used as flavoring in the cosmetics and…”
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The association of the Prognostic Nutritional Index (PNI) and Neutrophil-Lymphocyte Ratio (NLR) with cachexia in cancer patients by Leão Silva, A.C., Santos, J.M., Tavares, V., Ferreira, T., Dias, V.D.R., da Silva, C.M.S., e Silva, M.P.C., Medeiros, R.

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A new approach for the direct acylation of bio-oil enriched with levoglucosan: Kinetic study and lipase thermostability by do Nascimento, Marcelo A., Leão, Raquel A.C., Froidevaux, Rénato, Wojcieszak, Robert, de Souza, Rodrigo O.M. A., Itabaiana, Ivaldo

“…Lignocellulosic biomass can be valorized by fast pyrolysis, generating a bio-oil with levoglucosan (BoE), anhydrous sugar applied as building block for several…”
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Thermal catalytic cracking of crude palm oil at pilot scale: Effect of the percentage of Na2CO3 on the quality of biofuels by Mancio, A.A., da Costa, K.M.B., Ferreira, C.C., Santos, M.C., Lhamas, D.E.L., da Mota, S.A.P., Leão, R.A.C., de Souza, R.O.M.A., Araújo, M.E., Borges, L.E.P., Machado, N.T.

“…•Study of thermal catalytic cracking at a pilot scale (reactor of 143L).•Acid value decreased as the sodium carbonate percentage increased.•The GC–MS analysis…”
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New Biosilified Pd-lipase hybrid biocatalysts for dynamic resolution of amines by de Souza, Stefânia P., Leão, Raquel A.C., Bassut, Jonathan F., Leal, Ivana C.R., Wang, Shuai, Ding, Qiqi, Li, Yingying, Lam, Frank Leung-Yuk, de Souza, Rodrigo O.M.A., Itabaiana Jr, Ivaldo

“…[Display omitted] •A new protocol for immobilization of lipase CaLB on Biosilified Pd nanoparticles.•DKR of α-methylbenzylamine in one step with a new hybrid…”
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Continuous-flow protocol for the synthesis of enantiomerically pure intermediates of anti epilepsy and anti tuberculosis active pharmaceutical ingredients by Aguiar, Renata M, Leão, Raquel A C, Mata, Alejandro, Cantillo, David, Kappe, C Oliver, Miranda, Leandro S M, de Souza, Rodrigo O M A

“…Continuous-flow production of chiral intermediates plays an important role in the development of building blocks for Active Pharmaceutical Ingredients (APIs),…”
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Lipase-catalyzed acylation of levoglucosan in continuous flow: antibacterial and biosurfactant studies by do Nascimento, Marcelo A, Vargas, Juan P C, Rodrigues, José G A, Leão, Raquel A C, de Moura, Patricia H B, Leal, Ivana C R, Bassut, Jonathan, de Souza, Rodrigo O M A, Wojcieszak, Robert, Itabaiana, Jr, Ivaldo

“…Studies involving the transformation of lignocellulosic biomass into high value-added chemical products have been intensively conducted in recent years. Its…”
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Continuous‐Flow Synthesis of (R)‐Propylene Carbonate: An Important Intermediate in the Synthesis of Tenofovir by Suveges, Nicolas S., Rodriguez, Anderson A., Diederichs, Carla C., de Souza, Stefania P., Leão, Raquel A. C., Miranda, Leandro S. M., Horta, Bruno A. C., Pedraza, Sérgio F., de Carvalho, Otavio V., Pais, Karla C., Terra, José H. C., de Souza, Rodrigo O. M. A.

“…(R)‐Propylene carbonate is an important intermediate in the synthesis of tenofovir pro‐drugs such as tenofovir alafenamide fumarate (TAF) and tenofovir…”
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From Immobilization to Catalyst Use: A Complete Continuous‐Flow Approach Towards the Use of Immobilized Organocatalysts by Oliveira, Pedro H. R., S. Santos, Bruno M., Leão, Raquel A. C., Miranda, Leandro S. M., San Gil, Rosane A. S., Souza, Rodrigo O. M. A., Finelli, Fernanda G.

“…The combination of chiral supported‐organocatalysts and flow chemistry promotes the sustainable production of enantioenriched compounds providing a very…”
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Theoretical studies and NMR assay of coumarins and neoflavanones derivatives as potential inhibitors of acetylcholinesterase by de Souza, Luana G., Moraes, Paula F., Leão, Raquel A.C., Costa, Paulo R.R., Soares, Rosemberg O., Pascutti, Pedro G., Figueroa-Villar, Jose D., Rennó, Magdalena N.

“…[Display omitted] •Synthesized coumarins and neoflavanones derivatives as potential inhibitors of Acetylcholinesterase.•The coumarin (12b) presented a good…”
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Continuous-flow CvFAP photodecarboxylation of palmitic acid under environmentally friendly conditions by Benincá, Luiza A.D., França, Alexandre S., Brêda, Gabriela C., Leão, Raquel A.C., Almeida, Rodrigo V., Hollmann, Frank, de Souza, Rodrigo O.M.A.

“…•High power LED on biocatalyzed photodecarboxylation reactions.•Continuous-flow photodecarboxylation mediated by CvFAP.•Sunlight and solar panel as alternative…”
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Continuous flow synthesis of the lamivudine precursor L-Menthyl Glyoxylate by Azevedo, Lais S. D., Aguillon, Anderson R., Lima, Marcelo T., Leão, Raquel A. C., de Souza, Rodrigo O. M. A.

“…Lamivudine (3TC) is a drug in the antiretroviral class used to treat AIDS / HIV. Featuring two chiral centers, 3TC has two pairs of diastereomers, of which cis…”
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Two step continuous-flow synthesis of benzocaine by França, Alexandre de S., Leão, Raquel A. C., de Souza, Rodrigo O. M. A.

“…Benzocaine (ethyl p -aminobenzoate), ethyl ester of p -aminobenzoic acid, is an anesthetic acting as a blocker of the nerve impulses and reducing the…”
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