Search Results - "Le, Ying"
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1
Screening and identification of key candidate genes and pathways in myelodysplastic syndrome by bioinformatic analysis
Published in PeerJ (San Francisco, CA) (29-11-2019)“…Myelodysplastic syndrome (MDS) is a heterogeneous hematologic malignancy derived from hematopoietic stem cells and the molecular mechanism of MDS remains…”
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2
Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and Dysfunction
Published in Hypertension (Dallas, Tex. 1979) (01-12-2017)“…The apelin pathway has emerged as a critical regulator of cardiovascular homeostasis and disease. However, the exact role of pyr1-apelin-13 in angiotensin…”
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3
Green Tea Polyphenol EGCG Attenuates MDSCs-mediated Immunosuppression through Canonical and Non-Canonical Pathways in a 4T1 Murine Breast Cancer Model
Published in Nutrients (10-04-2020)“…Several studies in the past decades have reported anti-tumor activity of the bioactive compounds extracted from tea leaves, with a focus on the compound…”
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4
Metrnl deficiency decreases blood HDL cholesterol and increases blood triglyceride
Published in Acta pharmacologica Sinica (01-12-2020)“…Dyslipidemia is a risk factor for cardiovascular diseases and type 2 diabetes. Several adipokines play important roles in modulation of blood lipids. Metrnl is…”
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5
Role of NLRP3 inflammasome in hepatocellular carcinoma: A double-edged sword
Published in International immunopharmacology (01-05-2023)“…[Display omitted] •NLRP3 inflammasome related inflammatory signaling pathway plays an promoting role in HCC.•Classical pyroptosis mediated by NLRP3…”
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6
Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway
Published in PloS one (12-12-2012)“…This study was to investigate the effect of nicotine on insulin sensitivity and explore the underlying mechanisms. Treatment of Sprague-Dawley rats with…”
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7
Role of targeting TLR4 signaling axis in liver-related diseases
Published in Pathology, research and practice (01-04-2023)“…Toll-like receptor 4 (TLR4) plays an important role as a key signal-receiving transmembrane protein molecule in the liver, and substances that target the liver…”
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8
The impact of dynamic traffic and wind conditions on green infrastructure performance to improve local air quality
Published in The Science of the total environment (20-03-2024)“…Road traffic represents the dominant source of air pollution in urban street canyons. Local wind conditions greatly impacts the dispersion of these pollutants,…”
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9
Single image dehazing enhancement based on retinal mechanism
Published in Multimedia tools and applications (05-01-2024)“…Based on the hierarchical transmission and interaction response characteristics of visual information in retina, we propose a single image dehazing enhancement…”
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10
Impact of glycemic control on the association of endothelial dysfunction and coronary artery disease in patients with type 2 diabetes mellitus
Published in Cardiovascular diabetology (13-03-2021)“…We investigated whether glycemic control affects the relation between endothelial dysfunction and coronary artery disease in patients with type 2 diabetes…”
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11
Research Progress of Graphene‐Based Rubber Nanocomposites
Published in Polymer composites (01-04-2018)“…Nowadays, rubber nanocomposites filled with graphene are endowed with promising future, because graphene has unique and outstanding mechanical, electrical, and…”
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12
Nuclear trafficking of bacterial effector proteins
Published in Cellular microbiology (01-06-2021)“…Bacterial pathogens can subvert host responses by producing effector proteins that directly target the nucleus of eukaryotic cells in animals and plants…”
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Research progress on the role of Ndfip1 (Nedd4 family interacting protein 1) in immune cells
Published in Allergologia et immunopathologia (2023)“…Nedd4 family interacting protein 1 ( ) was first mentioned in an article in 2000. Since its discovery, related studies have shown that this protein is…”
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Examining the effects of different forms of teacher feedback intervention for learners' cognitive and emotional interaction in online collaborative discussion: A visualization method for process mining based on text automatic analysis
Published in Education and information technologies (01-04-2024)“…Teacher feedback is the key to online collaborative discussion. To investigate the effects of different forms of teacher feedback intervention on learners'…”
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15
Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic
Published in Proceedings of the National Academy of Sciences - PNAS (08-12-2015)“…Arsenic is highly effective for treating acute promyelocytic leukemia (APL) and has shown significant promise against many other tumors. However, although its…”
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16
Toll‐like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2
Published in International journal of cancer (15-06-2019)“…Toll‐like receptors (TLRs) play critical roles in host defense after recognition of conserved microbial‐ and host‐derived components, and their dysregulation…”
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17
Fluorescence resonance energy transfer-based hybridization chain reaction for in situ visualization of tumor-related mRNA
Published in Chemical science (Cambridge) (01-01-2016)“…The ability to visualize tumor-related mRNA in single cells would distinguish whether they are cancer cells or normal cells, which holds great promise for…”
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Resveratrol Protects Vascular Endothelial Cells from High Glucose–Induced Apoptosis through Inhibition of NADPH Oxidase Activation–Driven Oxidative Stress
Published in CNS neuroscience & therapeutics (01-09-2013)“…Summary Introduction Hyperglycemia‐induced oxidative stress has been implicated in diabetic vascular complications in which NADPH oxidase is a major source of…”
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19
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Published in Proceedings of the National Academy of Sciences - PNAS (23-06-2020)“…Retinoic acid-inducible gene I (RIG-I) is up-regulated during granulocytic differentiation of acute promyelocytic leukemia (APL) cells induced by all-trans…”
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Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer
Published in Oncogene (03-01-2022)“…The EMT (epithelial-to-mesenchymal-transition) subtype of gastric cancer (GC) is associated with poor treatment responses and unfavorable clinical outcomes…”
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