Search Results - "Le, X."

Metabolomics analysis of TiO2 nanoparticles induced toxicological effects on rice (Oryza sativa L.) by Wu, Biying, Zhu, Lizhong, Le, X. Chris

“…The wide occurrence and high environmental concentration of titanium dioxide nanoparticles (nano-TiO2) have raised concerns about their potential toxic effects…”
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A microRNA-initiated DNAzyme motor operating in living cells by Peng, Hanyong, Li, Xing-Fang, Zhang, Hongquan, Le, X. Chris

“…Synthetic DNA motors have great potential to mimic natural protein motors in cells but the operation of synthetic DNA motors in living cells remains…”
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Exponential Isothermal Amplification of Nucleic Acids and Assays for Proteins, Cells, Small Molecules, and Enzyme Activities: An EXPAR Example by Reid, Michael S., Le, X. Chris, Zhang, Hongquan

“…Isothermal exponential amplification techniques, such as strand‐displacement amplification (SDA), rolling circle amplification (RCA), loop‐mediated isothermal…”
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Signal Amplification by the trans-Cleavage Activity of CRISPR-Cas Systems: Kinetics and Performance by Feng, Wei, Zhang, Hongquan, Le, X. Chris

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Metabolomics and transcriptomics reveal defense mechanism of rice (Oryza sativa) grains under stress of 2,2′,4,4′-tetrabromodiphenyl ether by Chen, Jie, Le, X. Chris, Zhu, Lizhong

“…2,2′,4,4′-Tetrabromodiphenyl ether (BDE-47), a predominant polybrominated diphenyl ether (PBDE), has received extensive attention for its potential…”
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Analytical Advances in Detecting SARS-CoV‑2 and Further Research Needs for COVID-19 Testing by Le, X. Chris

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Split Locations and Secondary Structures of a DNAzyme Critical to Binding-Assembled Multicomponent Nucleic Acid Enzymes for Protein Detection by Cao, Yiren, Zhang, Hongquan, Le, X. Chris

“…RNA-cleaving DNAzymes and their multicomponent nucleic acid enzymes (MNAzymes) have been successfully used to detect nucleic acids and proteins. The…”
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DNAzyme-Mediated Assays for Amplified Detection of Nucleic Acids and Proteins by Peng, Hanyong, Newbigging, Ashley M, Wang, Zhixin, Tao, Jeffrey, Deng, Wenchan, Le, X. Chris, Zhang, Hongquan

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Label-free detection of biomolecules using inductively coupled plasma mass spectrometry (ICP-MS) by Hu, Jianyu, Yan, Xiaowen, Chris Le, X.

“…Bioassays using inductively coupled plasma mass spectrometry (ICP-MS) have gained increasing attention because of the high sensitivity of ICP-MS and the…”
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DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins by Zhang, Hongquan, Li, Feng, Dever, Brittany, Li, Xing-Fang, Le, X. Chris

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Binding-Induced Fluorescence Turn-On Assay Using Aptamer-Functionalized Silver Nanocluster DNA Probes by Li, Jingjing, Zhong, Xiaoqin, Zhang, Hongquan, Le, X. Chris, Zhu, Jun-Jie

“…We present here a binding-induced fluorescence turn-on assay for protein detection. Key features of this assay include affinity binding-induced DNA…”
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Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine by Ali, M Monsur, Li, Feng, Zhang, Zhiqing, Zhang, Kaixiang, Kang, Dong-Ku, Ankrum, James A, Le, X Chris, Zhao, Weian

“…Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or RNA primer is amplified to form a long single stranded DNA or RNA…”
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Arsenic Binding to Proteins by Shen, Shengwen, Li, Xing-Fang, Cullen, William R, Weinfeld, Michael, Le, X. Chris

“…An overview of how arsenic binds to proteins is presented from an analytical and biochemical perspective. The binding affinity, kinetics and speciation of…”
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Molecular Diagnosis of COVID-19: Challenges and Research Needs by Feng, Wei, Newbigging, Ashley M, Le, Connie, Pang, Bo, Peng, Hanyong, Cao, Yiren, Wu, Jinjun, Abbas, Ghulam, Song, Jin, Wang, Dian-Bing, Cui, Mengmeng, Tao, Jeffrey, Tyrrell, D. Lorne, Zhang, Xian-En, Zhang, Hongquan, Le, X. Chris

“…Molecular diagnosis of COVID-19 primarily relies on the detection of RNA of the SARS-CoV-2 virus, the causative infectious agent of the pandemic. Reverse…”
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Development of a DNAzyme Walker for the Detection of APE1 in Living Cancer Cells by Tao, Jeffrey, Zhang, Hongquan, Weinfeld, Michael, Le, X. Chris

“…DNAzyme walker technology is a compelling option for bioanalytical and drug delivery applications. While nucleic acid and protein targets have been used to…”
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Binding-Induced Formation of DNA Three-Way Junctions and Its Application to Protein Detection and DNA Strand Displacement by Li, Feng, Lin, Yanwen, Le, X. Chris

“…DNA three-way junctions (DNA TWJs) are important building blocks to construct DNA architectures and dynamic assemblies. We describe here a binding-induced DNA…”
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Binding-Induced DNA Nanomachines Triggered by Proteins and Nucleic Acids by Zhang, Hongquan, Lai, Maode, Zuehlke, Albert, Peng, Hanyong, Li, Xing-Fang, Le, X. Chris

“…We introduce the concept and operation of a binding‐induced DNA nanomachine that can be activated by proteins and nucleic acids. This new type of nanomachine…”
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Arsenic species in electronic cigarettes: Determination and potential health risk by Liu, Qingqing, Huang, Chengzhi, Chris Le, X.

“…Human exposure to contaminants from electronic cigarettes (e-cigarettes) and the associated health effects are poorly understood. There has been no report on…”
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CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules by Feng, Wei, Newbigging, Ashley M, Tao, Jeffrey, Cao, Yiren, Peng, Hanyong, Le, Connie, Wu, Jinjun, Pang, Bo, Li, Juan, Tyrrell, D. Lorne, Zhang, Hongquan, Le, X. Chris

“…Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) protein systems have transformed the field of genome editing and…”
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Signal Amplification in Living Cells: A Review of microRNA Detection and Imaging by Peng, Hanyong, Newbigging, Ashley M, Reid, Michael S, Uppal, Jagdeesh S, Xu, Jingyang, Zhang, Hongquan, Le, X. Chris

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