Search Results - "Le, Phuong M."

Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis by Le, Phuong M, Andreeff, Michael, Battula, Venkata Lokesh

“…The bone marrow microenvironment, also known as the bone marrow niche, is a complex network of cell types and acellular factors that supports normal…”
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Progress toward HIV elimination goals: trends in and projections of annual HIV testing and condom use in Africa by Nguyen, Phuong T., Gilmour, Stuart, Le, Phuong M., Onishi, Kazunari, Kato, Kosuke, Nguyen, Huy V.

“…To estimate trends in and projections of annual HIV testing and condom use at last higher-risk sex; and to calculate the probability of reaching key UNAIDS's…”
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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival by Kornblau, Steven M, Ruvolo, Peter P, Wang, Rui-Yu, Battula, V Lokesh, Shpall, Elizabeth J, Ruvolo, Vivian R, McQueen, Teresa, Qui, YiHua, Zeng, Zhihong, Pierce, Sherry, Jacamo, Rodrigo, Yoo, Suk-Young, Le, Phuong M, Sun, Jeffrey, Hail, Jr, Numsen, Konopleva, Marina, Andreeff, Michael

“…Mesenchymal stromal cells (MSC) support acute myeloid leukemia (AML) cell survival in the bone marrow (BM) microenvironment. Protein expression profiles of…”
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Immune Cells Localize to Sites of Corneal Erosions in C57BL/6 Mice by Le, Phuong M, Pal-Ghosh, Sonali, Menko, A Sue, Stepp, Mary Ann

“…Recurrent epithelial erosions develop in the cornea due to prior injury or genetic predisposition. Studies of recurrent erosions in animal models allow us to…”
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AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth by Battula, V Lokesh, Le, Phuong M, Sun, Jeffrey C, Nguyen, Khoa, Yuan, Bin, Zhou, Ximin, Sonnylal, Sonali, McQueen, Teresa, Ruvolo, Vivian, Michel, Keith A, Ling, Xiaoyang, Jacamo, Rodrigo, Shpall, Elizabeth, Wang, Zhiqiang, Rao, Arvind, Al-Atrash, Gheath, Konopleva, Marina, Davis, R Eric, Harrington, Melvyn A, Cahill, Catherine W, Bueso-Ramos, Carlos, Andreeff, Michael

“…Genotypic and phenotypic alterations in the bone marrow (BM) microenvironment, in particular in osteoprogenitor cells, have been shown to support…”
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Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma by Oliveira, Giacomo, Stromhaug, Kari, Klaeger, Susan, Kula, Tomasz, Frederick, Dennie T., Le, Phuong M., Forman, Juliet, Huang, Teddy, Li, Shuqiang, Zhang, Wandi, Xu, Qikai, Cieri, Nicoletta, Clauser, Karl R., Shukla, Sachet A., Neuberg, Donna, Justesen, Sune, MacBeath, Gavin, Carr, Steven A., Fritsch, Edward F., Hacohen, Nir, Sade-Feldman, Moshe, Livak, Kenneth J., Boland, Genevieve M., Ott, Patrick A., Keskin, Derin B., Wu, Catherine J.

“…Interactions between T cell receptors (TCRs) and their cognate tumour antigens are central to antitumour immune responses 1 – 3 ; however, the relationship…”
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A large peptidome dataset improves HLA class I epitope prediction across most of the human population by Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Lan Zhang, Guang, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.

“…Prediction of HLA epitopes is important for the development of cancer immunotherapies and vaccines. However, current prediction algorithms have limited…”
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Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer by Ouspenskaia, Tamara, Law, Travis, Clauser, Karl R., Klaeger, Susan, Sarkizova, Siranush, Aguet, François, Li, Bo, Christian, Elena, Knisbacher, Binyamin A., Le, Phuong M., Hartigan, Christina R., Keshishian, Hasmik, Apffel, Annie, Oliveira, Giacomo, Zhang, Wandi, Chen, Sarah, Chow, Yuen Ting, Ji, Zhe, Jungreis, Irwin, Shukla, Sachet A., Justesen, Sune, Bachireddy, Pavan, Kellis, Manolis, Getz, Gad, Hacohen, Nir, Keskin, Derin B., Carr, Steven A., Wu, Catherine J., Regev, Aviv

“…Tumor-associated epitopes presented on MHC-I that can activate the immune system against cancer cells are typically identified from annotated protein-coding…”
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Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial by Keskin, Derin B., Anandappa, Annabelle J., Sun, Jing, Tirosh, Itay, Mathewson, Nathan D., Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet A., Hu, Zhuting, Li, Letitia, Le, Phuong M., Allesøe, Rosa L., Richman, Alyssa R., Kowalczyk, Monika S., Abdelrahman, Sara, Geduldig, Jack E., Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J. Bryan, Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars R., Stevens, Jonathan, Lane, William J., Salazar, Andres M., Daley, Heather, Wen, Patrick Y., Chiocca, E. Antonio, Harden, Maegan, Lennon, Niall J., Gabriel, Stacey, Getz, Gad, Lander, Eric S., Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott J., Ligon, Keith L., Suvà, Mario L., Wucherpfennig, Kai W., Hacohen, Nir, Fritsch, Edward F., Livak, Kenneth J., Ott, Patrick A., Wu, Catherine J., Reardon, David A.

“…Neoantigens, which are derived from tumour-specific protein-coding mutations, are exempt from central tolerance, can generate robust immune responses 1 , 2 and…”
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Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface during Acute and Resolution Phases of Experimental Autoimmune Uveitis by Le, Phuong M., Mattapallil, Mary J., Caspi, Rachel R., Stepp, Mary Ann, Menko, A. Sue

“…Inflammation in the eye is tightly regulated to prevent vision impairment and irreversible blindness. Emerging evidence shows that immune cells are…”
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The ciliary zonules provide a pathway for immune cells to populate the avascular lens during eye development by DeDreu, JodiRae, Le, Phuong M, Menko, A. Sue

“…The eye is an immune-privileged site, with both vasculature and lymphatics absent from the central light path. Unique adaptations have made it possible for…”
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α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration by Quinn, Jeanne M, Wang, Yuou, Wood, Megan, Flozak, Annette S, Le, Phuong M, Yemelyanov, Alex, Oakes, Patrick W, Gottardi, Cara J

“…α-catenin (α-cat) displays force-dependent unfolding and binding to actin filaments through direct and indirect means, but features of adherens junction…”
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Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples by Klaeger, Susan, Apffel, Annie, Clauser, Karl R., Sarkizova, Siranush, Oliveira, Giacomo, Rachimi, Suzanna, Le, Phuong M., Tarren, Anna, Chea, Vipheaviny, Abelin, Jennifer G., Braun, David A., Ott, Patrick A., Keshishian, Hasmik, Hacohen, Nir, Keskin, Derin B., Wu, Catherine J., Carr, Steven A.

“…MS is the most effective method to directly identify peptides presented on human leukocyte antigen (HLA) molecules. However, current standard approaches often…”
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A physical picture of the mechanism of turbulent heat transfer from the wall by Le, Phuong M., Papavassiliou, Dimitrios V.

“…The present work investigates the correlation between the velocity and the temperature field in wall turbulence using direct numerical simulation of turbulent…”
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Mass Spectrometry Based Identification of Novel HLA Class I Restricted Peptides in Merkel Cell Carcinoma by Rachimi, Suzanna, Klaeger, Susan, Lee, Patrick C., Le, Phuong M., Chea, Vipheaviny A., Carulli, Isabel P., Ananthapadmanabhan, Varsha, Tarren, Anna, Sarkizova, Siranush, Apffel, Annie, Clauser, Karl R., DeCaprio, James A., Carr, Steven A., Wu, Catherine J., Keskin, Derin B.

“…Highly polymorphic class I human leukocyte antigen (HLA‐I) molecules present endogenous peptides to CD8+ T cells, an essential part of immune regulation. This…”
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Cross-linking by epichlorohydrin and diepoxybutane correlates with cytotoxicity and leads to apoptosis in human leukemia (HL-60) cells by Le, Phuong M., Silvestri, Vanesa L., Redstone, Samuel C., Dunn, Jordanne B., Millard, Julie T.

“…The bifunctional alkylating agents epichlorohydrin (ECH) and diepoxybutane (DEB) have been linked to increased cancer risks in industrial workers. These…”
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Arsenic in the soil-rice system of the Mekong River delta by Dao, Hoan T., Dinh, Van M., Nguyen, Anh T. Q., Dang, Quan T., Nguyen, Hue T., Nguyen, Muu T., Nguyen, Duc T., Duong, Linh H., Nguyen, Anh Q., Pham, Anh T. M., Le, Trang Q., Hoang, Trang T. T., Dao, Trang T., Le, Phuong M., Nguyen, Tu N., Nguyen, Linh T., Tran, Thu T. M., Tran, Tien M., Nguyen, Minh N.

“…Arsenic (As) in rice has been known as a worldwide human health threat that results originally from the accumulation of As in soil in many rice cultivation…”
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On temperature prediction at low Re turbulent flows using the Churchill turbulent heat flux correlation by Le, Phuong M., Papavassiliou, Dimitrios V.

“…The present work investigates the prediction of mean temperature profiles in turbulent channel flow using the fraction of the heat flux due to turbulence…”
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Mesenchymal Stem Cells Differentiate into Osteoblasts in the Presence of AML Cells through Up-regulation of RUNX2 and Induce Chemo-resistance by Battula, V. Lokesh, PhD, Le, Phuong M, Sun, Jeffrey, Queen, Teresa Mc, Somanchi, Anitha, Wang, Rui-Yu, MD, Strunk, Dirk, PhD, Shpall, Elizabeth J., MD, Ruvolo, Peter, PhD, Kantarjian, Hagop, MD, Konopleva, Marina, MD, PhD, Andreeff, Michael, MD, PhD

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Optimal approaches for the use of DTP-HepB-Hib vaccines in Uniject™ in resource-poor settings by Guillermet, E, Dicko, H.M, Phuong, M. Le Thi, Hane, F, Jaillard, P, Gessner, B.D, Colombini, A

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