Search Results - "Le, Kevin C"

Identification of high affinity HER2 binding antibodies using CHO Fab surface display by Nguyen, Annalee W, Le, Kevin C, Maynard, Jennifer A

“…Abstract Discovery of monoclonal antibodies is most commonly performed using phage or yeast display but mammalian cells are used for production because of the…”
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Stem-like CD4 + T cells in perivascular tertiary lymphoid structures sustain autoimmune vasculitis by Sato, Yuki, Jain, Abhinav, Ohtsuki, Shozo, Okuyama, Hirohisa, Sturmlechner, Ines, Takashima, Yoshinori, Le, Kevin-Phu C, Bois, Melanie C, Berry, Gerald J, Warrington, Kenneth J, Goronzy, Jörg J, Weyand, Cornelia M

“…Autoimmune vasculitis of the medium and large elastic arteries can cause blindness, stroke, aortic arch syndrome, and aortic aneurysm. The disease is often…”
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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes by Hsieh, Ching-Lin, Goldsmith, Jory A, Schaub, Jeffrey M, DiVenere, Andrea M, Kuo, Hung-Che, Javanmardi, Kamyab, Le, Kevin C, Wrapp, Daniel, Lee, Alison G, Liu, Yutong, Chou, Chia-Wei, Byrne, Patrick O, Hjorth, Christy K, Johnson, Nicole V, Ludes-Meyers, John, Nguyen, Annalee W, Park, Juyeon, Wang, Nianshuang, Amengor, Dzifa, Lavinder, Jason J, Ippolito, Gregory C, Maynard, Jennifer A, Finkelstein, Ilya J, McLellan, Jason S

“…The coronavirus disease 2019 (COVID-19) pandemic has led to accelerated efforts to develop therapeutics and vaccines. A key target of these efforts is the…”
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Expression and characterization of SARS-CoV-2 spike proteins by Schaub, Jeffrey M., Chou, Chia-Wei, Kuo, Hung-Che, Javanmardi, Kamyab, Hsieh, Ching-Lin, Goldsmith, Jory, DiVenere, Andrea M., Le, Kevin C., Wrapp, Daniel, Byrne, Patrick O., Hjorth, Christy K., Johnson, Nicole V., Ludes-Meyers, John, Nguyen, Annalee W., Wang, Nianshuang, Lavinder, Jason J., Ippolito, Gregory C., Maynard, Jennifer A., McLellan, Jason S., Finkelstein, Ilya J.

“…The severe acute respiratory syndrome coronavirus 2 spike protein is a critical component of coronavirus disease 2019 vaccines and diagnostics and is also a…”
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Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses by Silva, Rui P, Huang, Yimin, Nguyen, Annalee W, Hsieh, Ching-Lin, Olaluwoye, Oladimeji S, Kaoud, Tamer S, Wilen, Rebecca E, Qerqez, Ahlam N, Park, Jun-Gyu, Khalil, Ahmed M, Azouz, Laura R, Le, Kevin C, Bohanon, Amanda L, DiVenere, Andrea M, Liu, Yutong, Lee, Alison G, Amengor, Dzifa A, Shoemaker, Sophie R, Costello, Shawn M, Padlan, Eduardo A, Marqusee, Susan, Martinez-Sobrido, Luis, Dalby, Kevin N, D'Arcy, Sheena, McLellan, Jason S, Maynard, Jennifer A

“…To address the ongoing SARS-CoV-2 pandemic and prepare for future coronavirus outbreaks, understanding the protective potential of epitopes conserved across…”
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Host oxidative folding pathways offer novel anti-chikungunya virus drug targets with broad spectrum potential by Langsjoen, Rose M., Auguste, Albert J., Rossi, Shannan L., Roundy, Christopher M., Penate, Heidy N., Kastis, Maria, Schnizlein, Matthew K., Le, Kevin C., Haller, Sherry L., Chen, Rubing, Watowich, Stanley J., Weaver, Scott C.

“…Alphaviruses require conserved cysteine residues for proper folding and assembly of the E1 and E2 envelope glycoproteins, and likely depend on host protein…”
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Abstract 060: Endovascular Thrombectomy for Posterior Cerebral Artery in the National Inpatient Sample (EaT PeCAN pIeS) by Brake, Aaron B, Fry, Lane T, Heskett, Cody E, Alkiswani, Abdul‐Rahman S, LeBeau, Gabriel T, De Stefano, Frank, Lei, Catherine M, Le, Kevin C, Rouse, Adam D, Peterson, Jeremy A, Ebersole, Koji

“…Introduction Posterior cerebral artery acute ischemic strokes (PCA‐AIS) comprise around 2% of all acute ischemic strokes and often results in significant…”
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Subclinical Aortic Inflammation in Patients with Polymyalgia Rheumatica by Kaymakci, Mahmut S, Berry, Gerald J, Langenfeld, Hannah E, Hanson, Andrew C, Crowson, Cynthia S, Bois, Melanie C, Schaff, Hartzell V, Sato, Yuki, Le, Kevin-Phu C, Koster, Matthew J, Weyand, Cornelia M, Warrington, Kenneth J

“…To examine the clinicopathologic features of patients with polymyalgia rheumatica (PMR) who had thoracic aorta repair surgery. Findings were compared with…”
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