Search Results - "Le, Hoang V."

Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer by Akins, Nicholas S, Nielson, Tanner C, Le, Hoang V

“…Cancer cells have a very different metabolism from that of normal cells from which they are derived. Their metabolism is elevated, which allows them to sustain…”
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A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse by Khan, Md Imdadul H., Sawyer, Benjamin J., Akins, Nicholas S., Le, Hoang V.

“…Kappa opioid receptor (KOR) is a member of the opioid receptor system, the G protein-coupled receptors that are expressed throughout the peripheral and central…”
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Isolation of Two Plasticizers, Bis(2-Ethylhexyl) Terephthalate and Bis(2-Ethylhexyl) Phthalate, from Capparis spinosa L. Leaves by Kdimy, Ayoub, Kim, Seong Jong, Ali, Zulfiqar, Khan, Md Imdadul H, Tripathi, Siddharth K, El Hajjaji, Souad, Le, Hoang V

“…Many plants have been known to be contaminated and accumulate plasticizers from the environment, including water sources, soil, and atmosphere. Plasticizers…”
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Identification of Human Kinin-Forming Enzyme Inhibitors from Medicinal Herbs by Madkhali, Hassan, Tarawneh, Amer, Ali, Zulfiqar, Le, Hoang V., Cutler, Stephen J., Khan, Ikhlas A., Shariat-Madar, Zia

“…The goal of this study was to assess the pharmacological effects of black tea (Camellia sinensis var. assamica) water extract on human kinin-forming enzymes in…”
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Friendly Environmental Strategies to Recycle Zinc–Carbon Batteries for Excellent Gel Polymer Electrolyte (PVA-ZnSO4‑H2SO4) and Carbon Materials for Symmetrical Solid-State Supercapacitors by Vuong, Thuy Trang T., Phan, Huy-Trinh, Vu Thi Thu, Nga, Nguyen, Phi Long, Nguyen, Huy Tiep, Le, Hoang V., Nguyen, Nghia Trong, Phung, Thi Viet Bac, Le, Phuoc-Anh

“…In this report, we introduce a novel idea to prepare a redox additive in a gel polymer electrolyte system of PVA-ZnSO4-H2SO4 based on zinc–carbon battery…”
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Suppression of Hepatocellular Carcinoma by Inhibition of Overexpressed Ornithine Aminotransferase by Zigmond, Ehud, Ya’acov, Ami Ben, Lee, Hyunbeom, Lichtenstein, Yoav, Shalev, Zvi, Smith, Yoav, Zolotarov, Lidya, Ziv, Ehud, Kalman, Rony, Le, Hoang V, Lu, Hejun, Silverman, Richard B, Ilan, Yaron

“…Hepatocellular carcinoma is the second leading cause of cancer death worldwide. DNA microarray analysis identified the ornithine aminotransferase (OAT) gene as…”
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Trifluoroacetic Anhydride-Catalyzed Oxidation of Isonitriles by DMSO: A Rapid, Convenient Synthesis of Isocyanates by Le, Hoang V, Ganem, Bruce

“…A smooth and efficient oxidation of isonitriles to isocyanates by sulfoxides is catalyzed by trifluoroacetic anhydride. With use of DMSO as the oxidant and 5…”
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Phytochemistry, Biological Activities, Therapeutic Potential, and Socio‐Economic Value of the Caper Bush (Capparis Spinosa L.) by Kdimy, Ayoub, El Yadini, Meryem, Guaadaoui, Abdelkarim, Bourais, Ilhame, El Hajjaji, Souad, Le, Hoang V.

“…Capparis spinosa L., commonly known as the caper bush, is an aromatic plant growing in most of the Mediterranean basin and some parts of Western Asia. C…”
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Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction by Juncosa, Jose I, Takaya, Kenji, Le, Hoang V, Moschitto, Matthew J, Weerawarna, Pathum M, Mascarenhas, Romila, Liu, Dali, Dewey, Stephen L, Silverman, Richard B

“…γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system. Inhibition of GABA aminotransferase (GABA-AT), a pyridoxal…”
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Facile synthesis and effect of thermal treatment on MoO3−x@MoS2 (x = 0, 1) bilayer nanostructure: toward photoelectrochemical applications by Nguyen, Tien–Thanh, Nguyen, Tien Dai, Vu, Thi Bich, Dien, Luong Xuan, Le, Hoang V, Do, Hung Manh, Nguyen, Thanh Tung

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Allopregnanolone and neuroHIV: Potential benefits of neuroendocrine modulation in the era of antiretroviral therapy by Salahuddin, Mohammed F., Qrareya, Alaa N., Mahdi, Fakhri, Moss, Emaya, Akins, Nicholas S., Li, Jing, Le, Hoang V., Paris, Jason J.

“…Forty years into the HIV pandemic, approximately 50% of infected individuals still suffer from a constellation of neurological disorders collectively known as…”
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Synthesis and biological evaluation of tert-butyl ester and ethyl ester prodrugs of L-γ-methyleneglutamic acid amides for cancer by Khan, Md Imdadul H., Mahdi, Fakhri, Penfornis, Patrice, Akins, Nicholas S., Hossain, Md Imran, Kim, Seong Jong, Sulochana, Suresh P., Adam, Amna T., Tran, Tristan D., Tan, Chalet, Paolo Claudio, Pier, Paris, Jason J., Le, Hoang V.

“…[Display omitted] In cancer cells, glutaminolysis is the primary source of biosynthetic precursors. Recent efforts to develop amino acid analogues to inhibit…”
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Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: utility in synthetic and medicinal chemistry by Le, Hoang V., Ganem, Bruce

“…A convenient and efficient (one-step) oxidation is reported of commercially available tosylmethylisocyanide (TOSMIC) to form tosylmethylisocyanate, making this…”
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Hybrid amorphous MoSx-graphene protected Cu2O photocathode for better performance in H2 evolution by Le, Hoang V., Le, Ly T., Tran, Phong D., Chang, Jong-San, Dieu Thuy, Ung Thi, Liem, Nguyen Quang

“…This paper reports on a new strategy using a combination of graphene protective layer and amorphous molybdenum sulfide (MoSx) H2-evolving catalyst layer to…”
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Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, β-ketoesters, or β-ketoamides by Hossain, Md Imran, Khan, Md Imdadul H, Kim, Seong Jong, Le, Hoang V

“…Herein we report a method for the synthesis of 3,4,5-trisubstituted isoxazoles in water under mild basic conditions at room temperature via a [3 +…”
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Kappa opioid receptors internalization is protective against oxygen-glucose deprivation through β-arrestin activation and Akt-mediated signaling pathway by Xu, Jihong, Chen, Fang, Wang, Shuyan, Akins, Nicholas S., Hossain, Md Imran, Zhou, Yi, Huang, Jinxi, Ji, Jiafu, Xi, Jin, Lin, Wenzhen, Grothusen, John, Le, Hoang V., Liu, Renyu

“…Hypoxia induces reversible κ-opioid receptor (KOR) internalization similar to the internalization that is induced by KOR agonists. In the current study, we…”
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Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover by Mascarenhas, Romila, Le, Hoang V, Clevenger, Kenneth D, Lehrer, Helaina J, Ringe, Dagmar, Kelleher, Neil L, Silverman, Richard B, Liu, Dali

“…Potent mechanism-based inactivators can be rationally designed against pyridoxal 5′-phosphate (PLP)-dependent drug targets, such as ornithine aminotransferase…”
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Gold protective layer decoration and pn homojunction creation as novel strategies to improve photocatalytic activity and stability of the H2-evolving copper (I) oxide photocathode by Le, Hoang V., Tran, Phong D., Mai, Huy V., Ung, Thuy T.D., Nguyen, Liem Q.

“…p-type Cu2O (p-Cu2O) is a promising candidate for engineering of photocathodes for solar H2 generation but it suffers from the photo-induced corrosion process…”
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PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation by Wu, Rui, Sanishvili, Ruslan, Belitsky, Boris R., Juncosa, Jose I., Le, Hoang V., Lehrer, Helaina J. S., Farley, Michael, Silverman, Richard B., Petsko, Gregory A., Ringe, Dagmar, Liu, Dali

“…The Bacillus subtilis protein regulator of the gabTD operon and its own gene (GabR) is a transcriptional activator that regulates transcription of…”
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6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects by Akins, Nicholas S., Mishra, Nisha, Harris, Hannah M., Dudhipala, Narendar, Kim, Seong Jong, Keasling, Adam W., Majumdar, Soumyajit, Zjawiony, Jordan K., Paris, Jason J., Ashpole, Nicole M., Le, Hoang V.

“…Current common analgesics are mediated through the mu or kappa opioid receptor agonism. Unfortunately, selective mu or kappa receptor agonists often cause…”
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