Search Results - "Le, Ann"

Experience-based co-design (EBCD) with young people who offend: Innovating methodology to reach marginalised groups by Girling, Melissa, Le Couteur, Ann, Finch, Tracy

“…The mental health needs of young people who offend have become more widely recognised and attempting to meet these needs is now a global priority for…”
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Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase by Koh, Xin Yu, Koh, Xiao Hui, Hwang, Le-ann, Ferrer, Fernando Jose, Rahmat, Siti Aishah Binte, Lama, Dilraj, Lane, David P.

“…Recepteur d’origine nantais (RON) receptor tyrosine kinase (RTK) and its ligand, serum macrophage-stimulating protein (MSP), are well-established oncogenic…”
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A cross-sectional study exploring the relationship between burnout, absenteeism, and job performance among American nurses by Dyrbye, Liselotte N, Shanafelt, Tait D, Johnson, Pamela O, Johnson, Le Ann, Satele, Daniel, West, Colin P

“…Studies suggest a high prevalence of burnout among nurses. The aim of this study was to evaluate the relationship between burnout among nurses and absenteeism…”
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Extravasation of Noncytotoxic Drugs: A Review of the Literature by Le, Ann, Patel, Samit

“…Objective: Extravasation is a potential complication associated with intravenous therapy administration. Inadvertent leakage of medications with vesicant…”
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Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis by Rodgers, Mark, Marshall, David, Simmonds, Mark, Le Couteur, Ann, Biswas, Mousumi, Wright, Kath, Rai, Dheeraj, Palmer, Stephen, Stewart, Lesley, Hodgson, Robert

“…Early intensive applied behaviour analysis-based interventions are intensive interventions for autistic children that are often delivered on a one-to-one basis…”
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Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories by Lali, Ricky, Chong, Michael, Omidi, Arghavan, Mohammadi-Shemirani, Pedrum, Le, Ann, Cui, Edward, Paré, Guillaume

“…Rare variants are collectively numerous and may underlie a considerable proportion of complex disease risk. However, identifying genuine rare variant…”
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Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy by Yu Koh, Xin, Koh, Xiao Hui, Spiegelberg, Diana, Jha, Preeti, Nestor, Marika, Hwang, Le-ann, Tan, Ban Xiong, Lane, David Philip

“…The RON receptor tyrosine kinase is an exceptionally interesting target in oncology and immunology. It is not only overexpressed in a wide variety of tumors…”
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Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity by Zheng, Shunsheng, Koh, Xin Yu, Goh, Hui Chin, Rahmat, Siti Aishah B, Hwang, Le-Ann, Lane, David P

“…Chemotoxicity due to unwanted p53 activation in the bone marrow remains an unmet clinical challenge. Doxorubicin, a first-line chemotherapy drug, often causes…”
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Rapid whole-genome sequencing for genetic disease diagnosis in neonatal intensive care units by Saunders, Carol Jean, Miller, Neil Andrew, Soden, Sarah Elizabeth, Dinwiddie, Darrell Lee, Noll, Aaron, Alnadi, Noor Abu, Andraws, Nevene, Patterson, Melanie LeAnn, Krivohlavek, Lisa Ann, Fellis, Joel, Humphray, Sean, Saffrey, Peter, Kingsbury, Zoya, Weir, Jacqueline Claire, Betley, Jason, Grocock, Russell James, Margulies, Elliott Harrison, Farrow, Emily Gwendolyn, Artman, Michael, Safina, Nicole Pauline, Petrikin, Joshua Erin, Hall, Kevin Peter, Kingsmore, Stephen Francis

“…Monogenic diseases are frequent causes of neonatal morbidity and mortality, and disease presentations are often undifferentiated at birth. More than 3500…”
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Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision Medicine by Hwang, Le-Ann, Phang, Beng Hooi, Liew, Oi Wah, Iqbal, Jabed, Koh, Xiao Hui, Koh, Xin Yu, Othman, Rashidah, Xue, Yuezhen, Richards, A. Mark, Lane, David P., Sabapathy, Kanaga

“…The large number of mutations identified across all cancers represents an untapped reservoir of targets that can be useful for therapeutic targeting if highly…”
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Instrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells by Ling, Samantha Shi Min, Khoo, Lawrence Han Boon, Hwang, Le-Ann, Yeoh, Khay Guan, Ho, Bow

“…Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak…”
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Design features of a guideline implementation tool designed to increase awareness of a clinical practice guide to HIV rehabilitation: A qualitative process evaluation by Salbach, Nancy M., Solomon, Patricia, O'Brien, Kelly K., Worthington, Catherine, Baxter, Larry, Blanchard, Georgina, Casey, Alan, Chegwidden, Will, Dolan, Le‐Ann, Eby, Sarah, Gervais, Nicole

“…Rationale, aims, and objectives A comprehensive electronic guide (e‐module) describing an interprofessional, evidence‐informed approach to HIV rehabilitation…”
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Cross-cultural adaptation and content validation of the Singapore English version of EQ-5D-Y: a qualitative study by Lee-Yin Tan, Rachel, Ng, Zhi Min, Chen, Le Ann, Herdman, Michael, Luo, Nan

“…The EQ-5D-Y is a generic preference-weighted measure for children and adolescents which was developed within Europe. Two versions exist, the EQ-5D-Y-3L (Y-3L)…”
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Systematic review of tools to measure outcomes for young children with autism spectrum disorder by McConachie, Helen, Parr, Jeremy R, Glod, Magdalena, Hanratty, Jennifer, Livingstone, Nuala, Oono, Inalegwu P, Robalino, Shannon, Baird, Gillian, Beresford, Bryony, Charman, Tony, Garland, Deborah, Green, Jonathan, Gringras, Paul, Jones, Glenys, Law, James, Le Couteur, Ann S, Macdonald, Geraldine, McColl, Elaine M, Morris, Christopher, Rodgers, Jacqueline, Simonoff, Emily, Terwee, Caroline B, Williams, Katrina

“…The needs of children with autism spectrum disorder (ASD) are complex and this is reflected in the number and diversity of outcomes assessed and measurement…”
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Diagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation by Allgar, Victoria, Wright, Barry, Taylor, Amelia, Couter, Ann Le, Phillips, Helen

“…The aim was to investigate the agreement between the ADI-R Deaf adaptation and ADOS-2 Deaf adaptation overall diagnostic categorisation for autism (AUT) and a…”
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Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene by Park, Ki-Eun, Kaucher, Amy V., Powell, Anne, Waqas, Muhammad Salman, Sandmaier, Shelley E.S., Oatley, Melissa J., Park, Chi-Hun, Tibary, Ahmed, Donovan, David M., Blomberg, Le Ann, Lillico, Simon G., Whitelaw, C. Bruce A., Mileham, Alan, Telugu, Bhanu P., Oatley, Jon M.

“…Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model…”
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Falling through the gaps: exploring the role of integrated commissioning in improving transition from children's to adults' services for young people with long-term health conditions in England by Maniatopoulos, Gregory, Le Couteur, Ann, Vale, Luke, Colver, Allan

“…Objectives To explore the role of integrated commissioning in improving the transition of young people with long-term conditions from child to adult services…”
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Emotional and Behavioural Problems in Children with Autism Spectrum Disorder by Maskey, Morag, Warnell, Frances, Parr, Jeremy R., Le Couteur, Ann, McConachie, Helen

“…The type, frequency and inter-relationships of emotional and behavioural problems in 863 children with autism spectrum disorder (ASD) were investigated using…”
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A Community-based Assessment of Skin Care, Allergies, and Eczema (CASCADE): an atopic dermatitis primary prevention study using emollients-protocol for a randomized controlled trial by Eichner, Brian, Michaels, Le Ann C, Branca, Kelsey, Ramsey, Katrina, Mitchell, Julie, Morris, Cynthia D, Fagnan, Lyle J, Dolor, Rowena J, Elder, Nancy, Hahn, David L, Nease, Donald E, Lapidus, Jodi, Cibotti, Ricardo, Block, Julie, Simpson, Eric L

“…Atopic dermatitis (AD) is a common, chronic skin disorder often beginning in infancy. Skin barrier dysfunction early in life serves as a central event in the…”
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Returning Home: The Middle-Income Trap and Gendered Norms in Thailand by Le Mare, Ann, Promphaking, Buapun, Rigg, Jonathan

“…We personalise the middle‐income trap by exploring the experiences of migrants from north‐east Thailand, most of whom return to their natal villages as a…”
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