Search Results - "Lazzeroni, L C"

HPA axis genetic variation, cortisol and psychosis in major depression by Schatzberg, A F, Keller, J, Tennakoon, L, Lembke, A, Williams, G, Kraemer, F B, Sarginson, J E, Lazzeroni, L C, Murphy, G M

“…Genetic variation underlying hypothalamic pituitary adrenal (HPA) axis overactivity in healthy controls (HCs) and patients with severe forms of major…”
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P-values in genomics: Apparent precision masks high uncertainty by Lazzeroni, L C, Lu, Y, Belitskaya-Lévy, I

“…Scientists often interpret P- values as measures of the relative strength of statistical findings. This is common practice in large-scale genomic studies where…”
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The cost of large numbers of hypothesis tests on power, effect size and sample size by Lazzeroni, L C, Ray, A

“…Advances in high-throughput biology and computer science are driving an exponential increase in the number of hypothesis tests in genomics and other scientific…”
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A randomized trial of computer-based reminders and audit and feedback to improve HIV screening in a primary care setting by Sundaram, V, Lazzeroni, L C, Douglass, L R, Sanders, G D, Tempio, P, Owens, D K

“…Despite recommendations for voluntary HIV screening, few medical centres have implemented screening programmes. The objective of the study was to determine…”
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Linkage Disequilibrium and Gene Mapping: An Empirical Least-Squares Approach by Lazzeroni, Laura C.

“…This paper proposes a novel approach for fine-scale mapping of disease genes that is based on the well-known linkage-disequilibrium parameter δ. Using a very…”
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A conditional inference framework for extending the transmission/disequilibrium test by Lazzeroni, L C, Lange, K

“…The transmission/disequilibrium test (TDT) of Terwilliger and Ott [Hum Hered 1992;42:337-346] and Spielman et al. [Am J Hum Genet 1993;52:506-516] is widely…”
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ABCB1 (MDR1) predicts remission on P-gp substrates in chronic depression by Ray, A, Tennakoon, L, Keller, J, Sarginson, J E, Ryan, H S, Murphy, G M, Lazzeroni, L C, Trivedi, M H, Kocsis, J H, DeBattista, C, Schatzberg, A F

“…The hypothesis that allelic variation in the multidrug resistance-1 ( MDR1 or ABCB1 ) gene encoding the P -glycoprotein (P-gp) blood–brain barrier efflux pump…”
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In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects by Lech, W J, Wang, G, Yang, Y L, Chee, Y, Dorman, K, McCrae, D, Lazzeroni, L C, Erickson, J W, Sinsheimer, J S, Kaplan, A H

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cost-Effectiveness of Screening for HIV in the Era of Highly Active Antiretroviral Therapy by Sanders, Gillian D, Bayoumi, Ahmed M, Sundaram, Vandana, Bilir, S. Pinar, Neukermans, Christopher P, Rydzak, Chara E, Douglass, Lena R, Lazzeroni, Laura C, Holodniy, Mark, Owens, Douglas K

“…The authors estimate that routine HIV screening in health care settings with a 1 percent prevalence of HIV infection costs about $15,000 per quality-adjusted…”
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HPA axis genetic variation, cortisol and psychosis in major depression by Schatzberg, A.F, Keller, J, Tennakoon, L, Lembke, A, Williams, G, Kraemer, F.B, Sarginson, J.E, Lazzeroni, L.C, Murphy, G.M

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A chronology of fine-scale gene mapping by linkage disequilibrium by Lazzeroni, L.C.

“…The past decade produced several proposals for fine-scale gene mapping using linkage disequilibrium data. The suggested methods fall into two main groups,…”
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Accuracy, Precision, and Consistency of Expert HIV Type 1 Genotype Interpretation: An International Comparison (The GUESS Study) by Zolopa, Andrew R., Lazzeroni, Laura C., Rinehart, Alex, Vezinet, Françoise Brun, Clavel, François, Collier, Ann, Conway, Brian, Gulick, Roy M., Holodniy, Mark, Perno, Carlo-Frederico, Shafer, Robert W., Richman, Douglas D., Wainberg, Mark A., Kuritzkes, Daniel R.

“…Background. Resistance testing is considered standard of care in HIV medicine, but there is no standard interpretation system for genotype tests. We sought to…”
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Multipoint linkage map of the human pseudoautosomal region based on single-sperm typing : do double crossovers occur during male meiosis ? by SCHMITT, K, LAZZERONI, L. C, FOOTE, S, VOLLRATH, D, FISCHER, E. M. C, GORADIA, T. M, LANGE, K, PAGE, D. C, ARNHEIM, N

“…Sperm typing was used to measure recombination fractions among pseudoautosomal markers and the beginning of the X/Y-specific sequences located at the…”
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Multipoint mapping calculations for sperm-typing data by LAZZERONI, L. C, ARNHEIM, N, SCHMITT, K, LANGE, K

“…This paper explains how multipoint likelihoods can be computed for sperm-typing data. Experimental errors such as multiple sperm per tube, inadequate…”
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Allele sharing and allelic association I: Sib pair tests with increased power by Lazzeroni, Laura C.

“…Affected sib pair data contain information about allele sharing and allelic association. Either of these features can point to the presence of a risk‐related…”
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Markov Chains for Monte Carlo Tests of Genetic Equilibrium in Multidimensional Contingency Tables by Lazzeroni, Laura C., Lange, Kenneth

“…Hardy-Weinberg equilibrium and linkage equilibrium are fundamental concepts in population genetics. In practice, testing linkage equilibrium in haplotype data…”
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Physiological Correlates of Social Avoidance Behavior in Children and Adolescents With Fragile X Syndrome by Hall, Scott S., Ph.D, Lightbody, Amy A., Ph.D, Huffman, Lynne C., M.D, Lazzeroni, Laura C., Ph.D, Reiss, Allan L., M.D

“…Abstract Objective To investigate whether eye-gaze avoidance, a striking phenotypic feature in fragile X syndrome (FXS), is associated with high levels of…”
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Comparison of the Heritability of Schizophrenia and Endophenotypes in the COGS-1 Family Study by LIGHT, Gregory, GREENWOOD, Tiffany A, OLINCY, Ann, RADANT, Allen D, SEIDMAN, Larry J, SIEVER, Larry J, SILVERMAN, Jeremy M, SPROCK, Joyce, STONE, William S, SUGAR, Catherine A, TSUANG, Debby W, TSUANG, Ming T, SWERDLOW, Neal R, TURETSKY, Bruce I, BRAFF, David L, CALKINS, Monica E, FREEDMAN, Robert, GREEN, Michael F, GUR, Raquel E, GUR, Ruben C, LAZZERONI, Laura C, NUECHTERLEIN, Keith H

“…Twin and multiplex family studies have established significant heritability for schizophrenia (SZ), often summarized as 81%. The Consortium on the Genetics of…”
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Erratum: HPA axis genetic variation, cortisol and psychosis in major depression by Schatzberg, A F, Keller, J, Tennakoon, L, Lembke, A, Williams, G, Kraemer, F B, Sarginson, J E, Lazzeroni, L C, Murphy, G M

“…Correction to: Molecular Psychiatry (2014) 19, 220–227; doi:10.1038/mp.2013.129 In footnote a in Table 1 (‘Less than five total in the rare homozygous,…”
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Intraindividual Variability in Basic Reaction Time Predicts Middle-Aged and Older Pilots' Flight Simulator Performance by KENNEDY, Quinn, TAYLOR, Joy, HERALDEZ, Daniel, NODA, Art, LAZZERONI, Laura C, YESAVAGE, Jerome

“…Intraindividual variability (IIV) is negatively associated with cognitive test performance and is positively associated with age and some neurological…”
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