Search Results - "Lazou, Antigone"
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The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection
Published in International journal of molecular sciences (24-10-2020)“…Iron is an essential mineral participating in different functions of the organism under physiological conditions. Numerous biological processes, such as oxygen…”
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Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols
Published in British journal of pharmacology (01-12-2020)“…Diabetic patients are at increased risk of developing coronary artery disease and experience worse clinical outcomes following acute myocardial infarction…”
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Protecting the Mitochondria in Cardiac Disease
Published in International journal of molecular sciences (23-07-2022)“…Cardiac disease is a broad cluster of several diseases, which include coronary artery disease, valve disease, congenital heart disease, arrhythmia, and…”
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4
Effect of hypercholesterolaemia on myocardial function, ischaemia–reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning
Published in British journal of pharmacology (01-06-2017)“…Hypercholesterolaemia is considered to be a principle risk factor for cardiovascular disease, having direct negative effects on the myocardium itself, in…”
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Cardioprotective Effects of PPARβ/δ Activation against Ischemia/Reperfusion Injury in Rat Heart Are Associated with ALDH2 Upregulation, Amelioration of Oxidative Stress and Preservation of Mitochondrial Energy Production
Published in International journal of molecular sciences (15-06-2021)“…Accumulating evidence support the cardioprotective properties of the nuclear receptor peroxisome proliferator activated receptor β/δ (PPARβ/δ); however, the…”
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Diabetic Cardiomyopathy and Ischemic Heart Disease: Prevention and Therapy by Exercise and Conditioning
Published in International journal of molecular sciences (21-04-2020)“…Metabolic syndrome, diabetes, and ischemic heart disease are among the leading causes of death and disability in Western countries. Diabetic cardiomyopathy is…”
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Toxicity of airborne nanoparticles: Facts and challenges
Published in Environment international (01-08-2024)“…•Air pollution is the most significant environmental risk factor for living organisms.•Airborne Nanoparticles (NP < 100 nm) harm the respiratory,…”
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Pharmacological activation of PPARβ/δ preserves mitochondrial respiratory function in ischemia/reperfusion via stimulation of fatty acid oxidation-linked respiration and PGC-1α/NRF-1 signaling
Published in Frontiers in endocrinology (Lausanne) (15-08-2022)“…Myocardial ischemia/reperfusion (I/R) injury leads to significant impairment of cardiac function and remains the leading cause of morbidity and mortality…”
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Behavioral, metabolic, and molecular stress responses of marine bivalve Mytilus galloprovincialis during long-term acclimation at increasing ambient temperature
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-08-2007)“…The present study aimed to determine the thermal response of the Mediterranean mussel Mytilus galloprovincialis by integrating information from various levels…”
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Is Intrinsic Cardioprotection a Laboratory Phenomenon or a Clinically Relevant Tool to Salvage the Failing Heart?
Published in International journal of molecular sciences (01-11-2023)“…Cardiovascular diseases, especially ischemic heart disease, as a leading cause of heart failure (HF) and mortality, will not reduce over the coming decades…”
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Camphene as a Protective Agent in Myocardial Ischemia/Reperfusion Injury
Published in Antioxidants (01-04-2024)“…Myocardial ischemia/reperfusion injury (I/R) and the resulting heart failure is one of the main causes of mortality and morbidity worldwide. Camphene has been…”
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PPARβ/δ at the crossroads of energy metabolism, mitochondrial quality control and redox balance
Published in Journal of biological research (Thessalonikē, Greece) (01-07-2022)“…Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), member of the PPAR subfamily of nuclear receptors, is highly expressed in tissues with high rates of…”
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Effects of partial dietary supplementation of fish meal with soymeal on the stress and apoptosis response in the digestive system of common dentex (Dentex dentex)
Published in Journal of biological research (Thessalonikē, Greece) (21-12-2017)“…Background Soybean is a common alternative protein source of plant origin in aquafeeds as it has a reasonably balanced amino acid profile and is widely…”
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Sex-Related Effects on Cardiac Development and Disease
Published in Journal of cardiovascular development and disease (19-03-2022)“…Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality. Interestingly, male and female patients with CVD exhibit distinct…”
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Low Dose Administration of Glutamate Triggers a Non-Apoptotic, Autophagic Response in PC12 Cells
Published in Cellular physiology and biochemistry (01-11-2015)“…Background/Aims: Increasing amounts of the neurotransmitter glutamate are associated with excitotoxicity, a phenomenon related both to homeostatic processes…”
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The science behind soft skills: Do's and Don'ts for early career researchers and beyond. A review paper from the EU-CardioRNA COST Action CA17129
Published in Open research Europe (2023)“…Soft skills are the elementary management, personal, and interpersonal abilities that are vital for an individual to be efficient at workplace or in their…”
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Ischemic preconditioning: protection against myocardial necrosis and apoptosis
Published in Vascular health and risk management (2007)“…The phenomenon of ischemic preconditioning has been recognized as one of the most potent mechanisms to protect against myocardial ischemic injury. In…”
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Phosphorylation and activation of mitogen- and stress-activated protein kinase-1 in adult rat cardiac myocytes by G-protein-coupled receptor agonists requires both extracellular-signal-regulated kinase and p38 mitogen-activated protein kinase
Published in Biochemical journal (01-08-2002)“…G-protein-coupled receptor agonists are powerful stimulators of mitogen-activated protein kinase (MAPK) cascades in cardiac myocytes. However, little is known…”
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Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart
Published in Biochemical journal (01-06-1998)“…We investigated the ability of phenylephrine (PE), an alpha-adrenergic agonist and promoter of hypertrophic growth in the ventricular myocyte, to activate the…”
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Chronic inflammatory diseases, myocardial function and cardioprotection
Published in British journal of pharmacology (01-12-2020)“…The association between chronic inflammatory diseases (CIDs) and increased cardiovascular (CV) risk is well documented and can be a most threatening…”
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