Search Results - "Lazdins, Janis K."

Female genital schistosomiasis (FGS): from case reports to a call for concerted action against this neglected gynaecological disease by Christinet, Vanessa, Lazdins-Helds, Janis K., Stothard, J. Russell, Reinhard-Rupp, Jutta

“…[Display omitted] •Female genital schistosomiasis (FGS) is a forgotten gynaecological disease.•Since 1899, FGS has been constantly reported with many different…”
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Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch by Awadzi, K, Opoku, Nicholas O, Attah, Simon K, Lazdins-Helds, Janis K, Kuesel, Annette C

“…Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key…”
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Unresolved issues in anthelmintic pharmacology for helminthiases of humans by Geary, Timothy G., Woo, Katherine, McCarthy, James S., Mackenzie, Charles D., Horton, John, Prichard, Roger K., de Silva, Nilanthi R., Olliaro, Piero L., Lazdins-Helds, Janis K., Engels, Dirk A., Bundy, Donald A.

“…Helminth infections are an important constraint on the health and development of poor children and adults. Anthelmintic treatment programmes provide a safe and…”
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Drug Discovery for Kinetoplastid Diseases: Future Directions by Rao, Srinivasa P. S, Barrett, Michael P, Dranoff, Glenn, Faraday, Christopher J, Gimpelewicz, Claudio R, Hailu, Asrat, Jones, Catherine L, Kelly, John M, Lazdins-Helds, Janis K, Mäser, Pascal, Mengel, Jose, Mottram, Jeremy C, Mowbray, Charles E, Sacks, David L, Scott, Phillip, Späth, Gerald F, Tarleton, Rick L, Spector, Jonathan M, Diagana, Thierry T

“…Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis…”
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Strategic emphases for tropical diseases research: a TDR perspective by Remme, Jan H.F., Blas, Erik, Chitsulo, Lester, Desjeux, Philippe M.P., Engers, Howard D., Kanyok, Thomas P., Kengeya Kayondo, Jane F., Kioy, Deborah W., Kumaraswami, Vasanthapuram, Lazdins, Janis K., Nunn, Paul P., Oduola, Ayoade, Ridley, Robert G., Toure, Yeya T., Zicker, Fabio, Morel, Carlos M.

“…Setting priorities for health research is a difficult task, especially for the neglected diseases of the poor. A new approach to priority setting for tropical…”
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Gustavo Pedro Kouri Flores by Lazdins-Helds, Janis K., Noya, Oscar, Pelegrino, Jose Luis

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Strategic emphases for tropical diseases research: a TDR perspective by Remme, Jan H.F., Blas, Erik, Chitsulo, Lester, Desjeux, Philippe M.P., Engers, Howard D., Kanyok, Thomas P., Kayondo, Jane F.Kengeya, Kioy, Deborah W., Kumaraswami, Vasanthapuram, Lazdins, Janis K., Nunn, Paul P., Oduola, Ayoade, Ridley, Robert G., Toure, Yeya T., Zicker, Fabio, Morel, Carlos M.

“…Setting priorities for health research is a difficult task, especially for the neglected diseases of the poor. A new approach to priority setting for tropical…”
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Biochemical Criteria for Activated Macrophages by Karnovsky, Manfred L, Lazdins, Janis K

“…The designation “activated macrophage” was originally introduced to describe the state of macrophages that have an enhanced ability to phagocytize…”
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Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells by Lazdins, J K, Grell, M, Walker, M R, Woods-Cook, K, Scheurich, P, Pfizenmaier, K

“…Tumor necrosis factor (TNF) and lymphotoxin (LT) are highly pleiotropic cytokines that play a central role in regulating HIV-1 replication. These cytokines…”
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Macrophages as effector cells of protective immunity in murine schistosomiasis by James, S L, Lazdins, J K, Meltzer, M S, Sher, A

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In vitro Effect of$\alpha_{1}$-Acid Glycoprotein on the Anti-Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors by Lazdins, Janis K., Mestan, Jürgen, Goutte, Gerard, Walker, Maja R., Bold, Guido, Capraro, Hans Georg, Klimkait, Thomas

“…Protein binding can impair the potency of human immunodeficiency virus (HIV) protease inhibitors. Therefore, the activity of a novel compound, CGP 61755, was…”
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In vitro effect of transforming growth factor-beta on progression of HIV-1 infection in primary mononuclear phagocytes by Lazdins, JK, Klimkait, T, Woods-Cook, K, Walker, M, Alteri, E, Cox, D, Cerletti, N, Shipman, R, Bilbe, G, McMaster, G

“…In vitro-differentiated monocytes can be infected with the monocytotropic isolate of HIV-1/ADA. The infection is characterized by formation of giant cells and…”
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In Vitro Effect of α 1 ‐Acid Glycoprotein on the Anti‐Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors by Lazdins, Janis K., Mestan, Jürgen, Goutte, Gerard, Walker, Maja R., Bold, Guido, Capraro, Hans Georg, Klimkait, Thomas

“…Abstract only…”
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In Vitro Effect of α1-Acid Glycoprotein on the Anti—Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors by Lazdins, Janis K., Mestan, Jürgen, Goutte, Gerard, Walker, Maja R., Bold, Guido, Capraro, Hans Georg, Klimkait, Thomas

“…Protein binding can impair the potency of human immunodeficiency virus (HIV) protease inhibitors. Therefore, the activity of a novel compound, CGP 61755, was…”
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Activation of human monocyte-derived macrophages to kill schistosomula of Schistosoma mansoni in vitro by James, SL, Cook, KW, Lazdins, JK

“…Human peripheral blood monocytes from normal donors were isolated by elutriation and differentiated by culture in the presence or absence of various…”
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Anti-HIV-1 Activity in Vitro of Ceftazidime Degradation Products by Hobi, Reinhard, Hübscher, Ulrich, Neftel, Klaus, Alteri, Enrica, Poncioni, Bernard, Walker, Maja R, Woods-Cook, Kathie, Schneider, Peter, Lazdins, Janis K

“…Cephalosporins in aqueous solutions generate degradation products that inhibit in vitro HIV-1 replication in cell lines, as well as in primary cells…”
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The lipophilic muramyl peptide MTP-PE is a potent inhibitor of HIV replication in macrophages by Lazdins, J K, Woods-Cook, K, Walker, M, Alteri, E

“…Cultured monocyte-derived macrophages were productively infected with human immunodeficiency virus in vitro. Treatment of these cells shortly after infection…”
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Schistosoma mansoni: rapid isolation and purification of schistosomula of different developmental stages by centrifugation on discontinuous density gradients of Percoll by Lazdins, J K, Stein, M J, David, J R, Sher, A

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Lack of effect of desferrioxamine on in-vitro HIV-1 replication by Lazdins, J K, Alteri, E, Klimkait, T, Woods-Cook, K, Walker, M R, Goutte, G, Poncioni, B

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The replicative restriction of lymphocytotropic isolates of HIV-1 in macrophages is overcome by TGF-beta by Lazdins, J K, Klimkait, T, Woods-Cook, K, Walker, M, Alteri, E, Cox, D, Cerletti, N, Shipman, R, Bilbe, G, McMaster, G

“…In vitro exposure of human blood monocyte-derived macrophages to T-cell tropic human immunodeficiency virus (HIV) isolates fails to establish a productive…”
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