Search Results - "Lazarus, Howard M."

Treatment Patterns and Associated Health Care Costs Before and After Treatment Initiation Among Pulmonary Arterial Hypertension Patients in the United States by Burger, Charles D, Ozbay, A Burak, Lazarus, Howard M, Riehle, Ellen, Montejano, Leslie B, Lenhart, Gregory, White, R James

“…Despite multiple treatment options, the prognosis of pulmonary arterial hypertension (PAH) remains poor. PAH patients experience a high economic burden due to…”
Get full text

A trial design to maximize knowledge of the effects of rodatristat ethyl in the treatment of pulmonary arterial hypertension (ELEVATE 2) by Lazarus, Howard M., Denning, Jill, Wring, Stephen, Palacios, Michelle, Hoffman, Sidra, Crizer, Katelyn, Kamau‐Kelley, Watiri, Symonds, William, Feldman, Jeremy

“…Serotonin plays a key role in the development and maintenance of the pathobiology associated with pulmonary arterial hypertension (PAH). Platelet‐driven and…”
Get full text

Clinical significance of pulmonary hypertension in interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute's innovative drug development initiative—Group 3 pulmonary hypertension by Nikkho, Sylvia M., Richter, Manuel J., Shen, Eric, Abman, Steven H., Antoniou, Katerina, Chung, Jonathan, Fernandes, Peter, Hassoun, Paul, Lazarus, Howard M., Olschewski, Horst, Piccari, Lucilla, Psotka, Mitchell, Saggar, Rajan, Shlobin, Oksana A., Stockbridge, Norman, Vitulo, Patrizio, Vizza, Carmine Dario, Wort, Stephen J., Nathan, Steven D.

“…Pulmonary hypertension (PH) has been linked to worse outcomes in chronic lung diseases. The presence of PH in the setting of underlying Interstitial Lung…”
Get full text

Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis: Global Pharmacovigilance Data by Lasky, Joseph A., Criner, Gerard J., Lazarus, Howard M., Kohlbrenner, Veronika, Bender, Shaun, Richeldi, Luca

“…Introduction The safety and tolerability of nintedanib in patients with idiopathic pulmonary fibrosis (IPF) have been characterized using data from clinical…”
Get full text

Detection and Early Referral of Patients With Interstitial Lung Abnormalities: An Expert Survey Initiative by Hunninghake, Gary M, Goldin, Jonathan G, Kadoch, Michael A, Kropski, Jonathan A, Rosas, Ivan O, Wells, Athol U, Yadav, Ruchi, Lazarus, Howard M, Abtin, Fereidoun G, Corte, Tamera J, de Andrade, Joao A, Johannson, Kerri A, Kolb, Martin R, Lynch, David A, Oldham, Justin M, Spagnolo, Paolo, Strek, Mary E, Tomassetti, Sara, Washko, George R, White, Eric S

“…Interstitial lung abnormalities (ILA) may represent undiagnosed early-stage or subclinical interstitial lung disease (ILD). ILA are often observed incidentally…”
Get full text

Letter to the Editor on Nagendran et al by Lazarus, Howard M

Get full text

Safety and efficacy of rodatristat ethyl for the treatment of pulmonary arterial hypertension (ELEVATE-2): a dose-ranging, randomised, multicentre, phase 2b trial by Sitbon, Olivier, Skride, Andris, Feldman, Jeremy, Sahay, Sandeep, Shlobin, Oksana A, McLaughlin, Vallerie, Ghofrani, Hossein-Ardeschir, Langleben, David, Parsley, Ed, D'Souza, Gwyn, Marmon, Tonya, Kamau-Kelley, Watiri, Jones, Renee, Grewal, Ravi, Wring, Steve, Palacios, Michelle, Naik, Himanshu, Denning, Jill, Lazarus, Howard M, Humbert, Marc

“…The role of serotonin in pulmonary arterial hypertension has been extensively studied in recent decades, with preclinical data strongly indicating involvement…”
Get full text

A retrospective study of in-hospital mortality in patients with idiopathic pulmonary fibrosis between 2015 and 2018 by Durheim, Michael T., Judy, Jennifer, Bender, Shaun, Neely, Megan L., Baumer, Dorothy, Robinson, Scott B., Conoscenti, Craig S., Leonard, Thomas B., Lazarus, Howard M., Palmer, Scott M.

“…Hospitalizations are common in patients with idiopathic pulmonary fibrosis (IPF) and are associated with high mortality. We used data from the Premier…”
Get full text

Design of Idiopathic Pulmonary Fibrosis Clinical Trials in the Era of Approved Therapies by Kaner, Robert J, Bajwa, Ednan K, El-Amine, Moustapha, Gorina, Eduard, Gupta, Renu, Lazarus, Howard M, Luckhardt, Tracy R, Mouded, Majd, Posada, Kaity, Richeldi, Luca, Stauffer, John, Tutuncu, Ahmet, Martinez, Fernando J

“…Conversely, strong inducers could reduce levels of the antifibrotic drugs. [...]potential for DDIs should be evaluated in the early phases of new drug…”
Get full text

Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho by MacLean, Margaret R, Fanburg, Barry, Hill, Nicolas, Lazarus, Howard M, Pack, Thomas F, Palacios, Michelle, Penumatsa, Krishna C, Wring, Stephen A

“…Serotonin is often referred to as a "happy hormone" as it maintains good mood, well-being, and happiness. It is involved in communication between nerve cells…”
Get more information

Detection and Early Referral of Patients With Interstitial Lung Abnormalities by Hunninghake, Gary M., Goldin, Jonathan G., Kadoch, Michael A., Kropski, Jonathan A., Rosas, Ivan O., Wells, Athol U., Yadav, Ruchi, Lazarus, Howard M., Abtin, Fereidoun G., Corte, Tamera J., de Andrade, Joao A., Johannson, Kerri A., Kolb, Martin R., Lynch, David A., Oldham, Justin M., Spagnolo, Paolo, Strek, Mary E., Tomassetti, Sara, Washko, George R., White, Eric S., Abtin, Fereidoun, Antoniou, Katerina, Blackwell, Timothy, Brown, Kevin, Chung, Jonathan, Corte, Tamera, Crestani, Bruno, Crossno, Peter, Culver, Daniel, de Andrade, Joao, Deveraj, Anand, Flaherty, Kevin, Gudmundsson, Gunnar, Hatabu, Hiroto, Jacob, Joe, Johansson, Kerri, Kanne, Jeff, Kazerooni, Ella, Kolb, Martin, Lynch, David, Maher, Toby, Martinez, Fernando, Morais, Antonio, Nathan, Steven D., Noth, Imre, Oldham, Justin, Podolanczuk, Anna, Poletti, Venerino, Ravaglia, Claudia, Renzoni, Elizabetta, Richeldi, Luca, Rubin, Geoffrey, Ryerson, Chris, Sahoo, Debasis, Tomassetti, Sara, Spagnolo, Paolo, Strek, Mary E., Suh, Rob, Sverzellati, Nicola, Valeyre, Dominique, Walsh, Simon, Washko, George, White, Eric S.

“…Interstitial lung abnormalities (ILA) may represent undiagnosed early-stage or subclinical interstitial lung disease (ILD). ILA are often observed incidentally…”
Get full text