Search Results - "Lazarides, Alexander"
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Arthroscopic Remplissage for Anterior Shoulder Instability: A Systematic Review of Clinical and Biomechanical Studies
Published in Arthroscopy (01-02-2019)“…To examine the clinical outcomes and biomechanical data supporting the use of the remplissage procedure. A query of the Embase, PubMed, Scopus, and Web of…”
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Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database
Published in BMC cancer (14-10-2020)“…Historically, amputation was the primary surgical treatment for osteosarcoma of the extremities; however, with advancements in surgical techniques and…”
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3
A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer
Published in Science translational medicine (06-01-2016)“…Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic residual cancer in the tumor…”
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4
Soft Tissue Sarcoma of the Extremities: What Is the Value of Treating at High-volume Centers?
Published in Clinical orthopaedics and related research (01-04-2019)“…For many cancer types, survival is improved when patients receive management at treatment centers that encounter high numbers of patients annually. This…”
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5
Next-generation sequencing not superior to culture in periprosthetic joint infection diagnosis
Published in Journal of bone and joint surgery. British volume (01-01-2021)“…Use of molecular sequencing methods in periprosthetic joint infection (PJI) diagnosis and organism identification have gained popularity. Next-generation…”
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6
Atrx deletion impairs CGAS/STING signaling and increases sarcoma response to radiation and oncolytic herpesvirus
Published in The Journal of clinical investigation (01-07-2023)“…ATRX is one of the most frequently altered genes in solid tumors, and mutation is especially frequent in soft tissue sarcomas. However, the role of ATRX in…”
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7
Rotator cuff tears in young patients: a different disease than rotator cuff tears in elderly patients
Published in Journal of shoulder and elbow surgery (01-11-2015)“…Background The purpose of this study was to conduct a systematic review of the literature to evaluate the characteristics of injury and treatment outcomes of…”
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8
Locking plate augmentation of polymethylmethacrylate-filled distal femoral defects: A biomechanical study
Published in Journal of orthopaedic research (01-09-2024)“…Benign, locally aggressive tumors of the distal femur are typically treated with intralesional curettage and polymethylmethacrylate (PMMA) cementation…”
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Regional anesthesia is associated with improved metastasis free survival after surgical resection of bone sarcomas
Published in Journal of orthopaedic research (01-12-2023)“…There is increasing evidence that perioperative factors, including type of anesthesia, may be an important consideration regarding oncological disease…”
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10
The Efficacy of Peroxide Solutions in Decreasing Cutibacterium acnes Burden Around the Shoulder
Published in Journal of the American Academy of Orthopaedic Surgeons (01-01-2022)“…Cutibacterium acnes is a common pathogen associated with surgical site infection after shoulder surgery; current standard of care products are largely…”
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11
Mapping the Course of Recovery Following Limb-Salvage Surgery for Soft-Tissue Sarcoma of the Extremities
Published in Journal of bone and joint surgery. American volume (02-10-2024)“…Despite the goal of an acceptable functional result, the surgical treatment of soft-tissue sarcoma can portend a prolonged course of recovery. More…”
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12
The Role of Radiotherapy for Chordoma Patients Managed With Surgery: Analysis of the National Cancer Database
Published in Spine (Philadelphia, Pa. 1976) (15-06-2020)“…STUDY DESIGN.Retrospective review. OBJECTIVE.To determine if adjuvant radiation therapy (RT) improves overall survival (OS) following surgical resection of…”
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13
Cell-cycle phase progression analysis identifies three unique phenotypes in soft tissue sarcoma
Published in BMC cancer (17-10-2024)“…Loddo et al. (Br J Cancer 100:959-70, 2009) established the prognostic significance of cell cycle markers and "Cell-Cycle Phenotypes" in breast carcinoma. This…”
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14
Race is an independent predictor of survival in patients with soft tissue sarcoma of the extremities
Published in BMC cancer (27-04-2018)“…In the United States, race and socioeconomic status are well known predictors of adverse outcomes in several different cancers. Existing evidence suggests that…”
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15
Intraoperative angiography imaging correlates with wound complications following soft tissue sarcoma resection
Published in Journal of orthopaedic research (01-10-2022)“…For soft tissue sarcoma patients receiving preoperative radiation therapy, wound complications are common and potentially devastating. The purpose of this…”
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Tumor necrosis is an underappreciated histopathologic factor in the grading of chondrosarcoma
Published in BMC cancer (23-06-2023)“…Cartilaginous neoplasms can be challenging to grade; there is a need to create an evidence-based rubric for grading. The goal of this study was to identify…”
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17
Open Versus Core Needle Biopsy in Lower-Extremity Sarcoma: Current Practice Patterns and Patient Outcomes
Published in Journal of bone and joint surgery. American volume (19-07-2023)“…Historically, open biopsy (OB) was the gold standard for sarcoma diagnosis. Core needle biopsy (CNB) has become increasingly common. There are limited data…”
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Midterm Outcomes of a Fixed-Bearing Total Ankle Arthroplasty With Deformity Analysis
Published in Foot & ankle international (01-12-2017)“…Background: We present our results with an INBONE I (Wright Medical, Memphis, TN) prosthesis that have a minimum of 4 to 10 years of follow-up and include a…”
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Antibiotic Prophylaxis for Megaprosthetic Reconstructions: Drug and Dosing May Matter More than Duration
Published in Antimicrobial agents and chemotherapy (18-10-2022)“…In orthopedic oncology, the implant of a megaprosthetic device is standard of care after large-scale tumor resection involving segmental removal of bone…”
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Defining a textbook surgical outcome for patients undergoing surgical resection of intermediate and high‐grade soft tissue sarcomas of the extremities
Published in Journal of surgical oncology (01-10-2020)“…Background Quality measures for the surgical management soft tissue sarcoma of the extremity are limited. The purpose of this study was to define a textbook…”
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