Search Results - "Lazarev, N. V."

Inhibition of Chlamydial Infection by CRISPR/Cas9-SAM Mediated Enhancement of Human Peptidoglycan Recognition Proteins Gene Expression in HeLa Cells by Bobrovsky, P. A., Moroz, V. D., Lavrenova, V. N., Manuvera, V. A., Lazarev, V. N.

“…The global problem of emerging resistance of microorganisms to antibiotics makes the search for new natural substances with antibacterial properties relevant…”
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Complete Genome and Proteome of Acholeplasma laidlawii by Lazarev, V. N, Levitskii, S. A, Basovskii, Y. I, Chukin, M. M, Akopian, T. A, Vereshchagin, V. V, Kostrjukova, E. S, Kovaleva, G. Y, Kazanov, M. D, Malko, D. B, Vitreschak, A. G, Sernova, N. V, Gelfand, M. S, Demina, I. A, Serebryakova, M. V, Galyamina, M. A, Vtyurin, N. N, Rogov, S. I, Alexeev, D. G, Ladygina, V. G, Govorun, V. M

“…We present the complete genome sequence and proteogenomic map for Acholeplasma laidlawii PG-8A (class Mollicutes, order Acholeplasmatales, family…”
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Mutations in a 23S rRNA Gene of Chlamydia trachomatis Associated with Resistance to Macrolides by Misyurina, O Y, Chipitsyna, E V, Finashutina, Y P, Lazarev, V N, Akopian, T A, Savicheva, A M, Govorun, V M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antimicrobial peptides and their use in medicine by Lazarev, V. N, Govorun, V. M

“…The review presents the current classification of antimicrobial peptides (AMP), which are the main component of innate immunity. The mechanism of their action…”
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The genes of antimicrobial peptides for the therapy of intracellular infections by V N Lazarev, V N

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Specific Activation of the Expression of Growth Factor Genes in Expi293F Human Cells Using CRISPR/Cas9-SAM Technology Increases Their Proliferation by Bobrovsky, P A, Grafskaia, E N, Kharlampieva, D D, Manuvera, V A, Lazarev, V N

“…Human cell lines play an important role in biotechnology and pharmacology. For them to grow, they need complex nutrient media containing signaling proteins -…”
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Oligomerization of the IHF Protein in the Presence of Metal Cations by Gordienko, A. M., Dadinova, L. A., Petoukhov, M. V., Mozhaev, A. A., Manuvera, V. A., Lazarev, V. N., Shtykova, E. V.

“…The oligomeric state of the nucleoid-associated protein IHF (integration host factor) plays a significant role in the organization and compaction of the…”
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Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens by Grafskaia, E.N., Nadezhdin, K.D., Talyzina, I.A., Polina, N.F., Podgorny, O.V., Pavlova, E.R., Bashkirov, P.V., Kharlampieva, D.D., Bobrovsky, P.A., Latsis, I.A., Manuvera, V.A., Babenko, V.V., Trukhan, V.M., Arseniev, A.S., Klinov, D.V., Lazarev, V.N.

“…The rise of antibiotic resistance has necessitated the development of alternative strategies for the treatment of infectious diseases. Antimicrobial peptides…”
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Role of isopeptidolysis in the process of thrombolysis by Baskova, I.P., Kalabushev, S.N., Akhaev, D.N., Bobrovsky, P.A., Manuvera, V.A., Lazarev, V.N.

“…Known thrombolytic agents either break peptide bonds in the fibrin molecule or act as plasminogen activators, which also results in peptide bond cleavage. In…”
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Induced expression of melittin, an antimicrobial peptide, inhibits infection by Chlamydia trachomatis and Mycoplasma hominis in a HeLa cell line by LAZAREV, V. N, PARFENOVA, T. M, GULARYAN, S. K, MISYURINA, O. Yu, AKOPIAN, T. A, GOVORUN, V. M

“…As the number of pathogenic microbial strains resistant to different antibiotics increases, amphipathic peptides with antimicrobial activity are promising…”
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Effect of induced expression of an antimicrobial peptide melittin on Chlamydia trachomatis and Mycoplasma hominis infections in vivo by Lazarev, V.N., Shkarupeta, M.M., Titova, G.A., Kostrjukova, E.S., Akopian, T.A., Govorun, V.M.

“…A plasmid construct was designed in which the gene of antimicrobial peptide melittin is controlled by the tetracycline-responsive promoter of human…”
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Two novel transcriptional reporter systems for monitoring Helicobacter pylori stress responses by Belova, A.M., Basmanov, D.V., Babenko, V.V., Podgorny, O.V., Mitko, T.V., Prusakov, K.A., Klinov, D.V., Lazarev, V.N.

“…Helicobacter pylori, a human pathogen linked to many stomach diseases, is well adapted to colonize aggressive gastric environments, and its virulence factors…”
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Localization of C. trachomatis inc proteins in expression of their genes in HeLa cell culture by Shkarupeta, M. M, Kostrjukova, E. S, Lazarev, V. N, Levitskii, S. A, Basovskii, Yu. I, Govorun, V. M

“…Co-localization of Chlamydia trachomatis incorporation membrane proteins with cell organelles was studied in HeLa cell culture after transfection by expressing…”
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Hydrophobic domains determine localization of IncC and IncG full-length proteins of C. trachomatis during their expression in cultured HeLa cells by Basovskiy, Yu. I, Shkarupeta, M. M, Levitskiy, S. A, Kostryukova, E. S, Lazarev, V. N, Govorun, V. M

“…Plasmid vectors encoding hydrophilic (IncB, IncC, IncE, IncG) and hydrophobic (IncC, IncG) domains of C. trachomatis incorporation membrane proteins and…”
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Purification and characterisation of recombinant Bacteroides fragilis toxin-2 by Kharlampieva, D.D., Manuvera, V.A., Podgorny, O.V., Kovalchuk, S.I., Pobeguts, O.V., Altukhov, I.A., Alexeev, D.G., Lazarev, V.N., Govorun, V.M.

“…Fragilysin (BFT) is metalloprotease that is secreted by enterotoxigenic Bacteroides fragilis. Studying the mechanism of BFT interaction with intestinal…”
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Recombinant small heat shock protein from Acholeplasma laidlawii increases the Escherichia coli viability in thermal stress by selective protein rescue by Kayumov, A. R., Bogachev, M. I., Manuvera, V. A., Lazarev, V. N., Sabantsev, A. V., Artamonova, T. O., Borchsenius, S. N., Vishnyakov, I. E.

“…In both prokaryotes and eukaryotes, the survival at temperatures considerably exceeding the optimum is supported by intense synthesis of the so-called heat…”
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Proteins and peptides of the salivary gland secretion of medicinal leeches Hirudo verbana, H. medicinalis, and H. orientalis by Baskova, I P, Kostrjukova, E S, Vlasova, M A, Kharitonova, O V, Levitskiy, S A, Zavalova, L L, Moshkovskii, S A, Lazarev, V N

“…The protein and peptide composition of medicinal leech salivary gland secretion (SGS) was analyzed in preparations obtained in July from three species--Hirudo…”
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Expression of Chlamydia trachomatis inclusion membrane protein genes IncB and IncC in Escherichia coli by Kostrjukova, E S, Lazarev, V N, Titova, G A, Akopian, T A, Levitskii, S A, Govorun, V M

“…In this study, we have cloned the Chlamydia trachomatis genes incB and incC into the expression plasmid vectors from pET series for the subsequent isolation of…”
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Purification and functional analysis of recombinant Acholeplasma laidlawii histone-like HU protein by Levitskiy, S.A., Sycheva, A.M., Kharlampieva, D.D., Oberto, J., Kamashev, D.E., Serebryakova, M.V., Moshkovskii, S.A., Lazarev, V.N., Govorun, V.M.

“…HU is a most abundant DNA-binding protein in bacteria. This protein is conserved either in its heterodimeric form or in one of its homodimeric forms in all…”
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Recombinant destabilase from the medicinal leech: Preparation and properties by Kurdyumov, A. S., Manuvera, V. A., Akhaev, D. N., Baskova, I. P., Lazarev, V. N.

“…The procedure for obtaining an active recombinant destabilase from the medicinal leech in Escherichia coli cells was developed. The plasmids encoding an…”
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