Search Results - "Lazar, Shirley"

Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody by Rosenfeld, Ronit, Noy-Porat, Tal, Mechaly, Adva, Makdasi, Efi, Levy, Yinon, Alcalay, Ron, Falach, Reut, Aftalion, Moshe, Epstein, Eyal, Gur, David, Chitlaru, Theodor, Vitner, Einat B., Melamed, Sharon, Politi, Boaz, Zauberman, Ayelet, Lazar, Shirley, Beth-Din, Adi, Evgy, Yentl, Yitzhaki, Shmuel, Shapira, Shmuel C., Israely, Tomer, Mazor, Ohad

“…The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), exhibits high levels of mortality…”
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Rapid Amplicon Nanopore Sequencing (RANS) for the Differential Diagnosis of Monkeypox Virus and Other Vesicle-Forming Pathogens by Israeli, Ofir, Guedj-Dana, Yehoudit, Shifman, Ohad, Lazar, Shirley, Cohen-Gihon, Inbar, Amit, Sharon, Ben-Ami, Ronen, Paran, Nir, Schuster, Ofir, Weiss, Shay, Zvi, Anat, Beth-Din, Adi

“…As of July 2022, more than 16,000 laboratory-confirmed monkeypox (MPX) cases have been reported worldwide. Until recently, MPX was a rare viral disease seldom…”
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Evaluating the efficacy of RT-qPCR SARS-CoV-2 direct approaches in comparison to RNA extraction by Israeli, Ofir, Beth-Din, Adi, Paran, Nir, Stein, Dana, Lazar, Shirley, Weiss, Shay, Milrot, Elad, Atiya-Nasagi, Yafit, Yitzhaki, Shmuel, Laskar, Orly, Schuster, Ofir

“…The genetic identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is based on viral RNA extraction prior to RT-qPCR assay, however…”
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Centaur antibodies: Engineered chimeric equine-human recombinant antibodies by Rosenfeld, Ronit, Alcalay, Ron, Zvi, Anat, Ben-David, Alon, Noy-Porat, Tal, Chitlaru, Theodor, Epstein, Eyal, Israeli, Ofir, Lazar, Shirley, Caspi, Noa, Barnea, Ada, Dor, Eyal, Chomsky, Inbar, Pitel, Shani, Makdasi, Efi, Zichel, Ran, Mazor, Ohad

“…Hyper-immune antisera from large mammals, in particular horses, are routinely used for life-saving anti-intoxication intervention. While highly efficient, the…”
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Insights from genomic analysis of a novel Coxiella burnetii strain isolated in Israel by Cohen-Gihon, Inbar, Israeli, Ofir, Bilinsky, Gal, Vasker, Barak, Lazar, Shirley, Beth-Din, Adi, Zvi, Anat, Ghanem-Zoubi, Nesrin, Atiya-Nasagi, Yafit

“…The diagnosis of Q fever is challenging due to nonspecific symptoms and negative standard blood culture results. Serological testing through immunofluorescence…”
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A Novel Approach to Vaccine Development: Concomitant Pathogen Inactivation and Host Immune Stimulation by Peroxynitrite by Rotem, Shahar, Bar-Haim, Erez, Elia, Uri, Cohen, Hila, Lazar, Shirley, Cohen, Ofer, Chitlaru, Theodor, Gal, Yoav

“…The design of efficient vaccines for long-term protective immunity against pathogens represents an objective of utmost public health priority. In general, live…”
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Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice by Noy-Porat, Tal, Mechaly, Adva, Levy, Yinon, Makdasi, Efi, Alcalay, Ron, Gur, David, Aftalion, Moshe, Falach, Reut, Leviatan Ben-Arye, Shani, Lazar, Shirley, Zauberman, Ayelet, Epstein, Eyal, Chitlaru, Theodor, Weiss, Shay, Achdout, Hagit, Edgeworth, Jonathan D., Kikkeri, Raghavendra, Yu, Hai, Chen, Xi, Yitzhaki, Shmuel, Shapira, Shmuel C., Padler-Karavani, Vered, Mazor, Ohad, Rosenfeld, Ronit

“…Neutralizing antibodies represent a valuable therapeutic approach to countermeasure the current COVID-19 pandemic. Emergence of SARS-CoV-2 variants emphasizes…”
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Genome sequence of two novel virulent clinical strains of Burkholderia pseudomallei isolated from acute melioidosis cases imported to Israel from India and Thailand by Cohen-Gihon, Inbar, Zaide, Galia, Amit, Sharon, Zohar, Iris, Schwartz, Orna, Maor, Yasmin, Israeli, Ofir, Bilinsky, Gal, Israeli, Ma'ayan, Lazar, Shirley, Gur, David, Aftalion, Moshe, Zvi, Anat, Beth-Din, Adi, Bar-Haim, Erez, Elia, Uri, Cohen, Ofer, Mamroud, Emanuelle, Chitlaru, Theodor

“…Burkholderia pseudomallei, the etiological cause of melioidosis, is a soil saprophyte endemic in South-East Asia, where it constitutes a public health concern…”
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Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies by Noy-Porat, Tal, Edri, Avishay, Alcalay, Ron, Makdasi, Efi, Gur, David, Aftalion, Moshe, Evgy, Yentl, Beth-Din, Adi, Levy, Yinon, Epstein, Eyal, Radinsky, Olga, Zauberman, Ayelet, Lazar, Shirley, Yitzhaki, Shmuel, Marcus, Hadar, Porgador, Angel, Rosenfeld, Ronit, Mazor, Ohad

“…The use of passively-administered neutralizing antibodies is a promising approach for the prevention and treatment of SARS-CoV-2 infection. Antibody-mediated…”
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Enhanced production yields of rVSV-SARS-CoV-2 vaccine using Fibra-Cel ® macrocarriers by Cohen, Noam, Simon, Irit, Hazan, Ophir, Tal, Arnon, Tzadok, Hanan, Levin, Lilach, Girshengorn, Meni, Mimran, Lilach Cherry, Natan, Niva, Baruhi, Tzadok, David, Alon Ben, Rosen, Osnat, Shmaya, Shlomo, Borni, Sarah, Cohen, Noa, Lupu, Edith, Kedmi, Adi, Zilberman, Orian, Jayson, Avital, Monash, Arik, Dor, Eyal, Diamant, Eran, Goldvaser, Michael, Cohen-Gihon, Inbar, Israeli, Ofir, Lazar, Shirley, Shifman, Ohad, Beth-Din, Adi, Zvi, Anat, Oren, Ziv, Makovitzki, Arik, Lerer, Elad, Mimran, Avishai, Toister, Einat, Zichel, Ran, Adar, Yaakov, Epstein, Eyal

“…The COVID-19 pandemic has led to high global demand for vaccines to safeguard public health. To that end, our institute has developed a recombinant viral…”
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Rapid identification of unknown pathogens in environmental samples using a high-throughput sequencing-based approach by Israeli, Ofir, Cohen-Gihon, Inbar, Zvi, Anat, Lazar, Shirley, Shifman, Ohad, Levy, Haim, Tidhar, Avital, Beth-Din, Adi

“…In the event of a bioterror attack, a prompt, sensitive and definite identification of the agents involved is of major concern for confirmation of the event…”
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A rapid high-throughput sequencing-based approach for the identification of unknown bacterial pathogens in whole blood by Israeli, Ofir, Makdasi, Efi, Cohen-Gihon, Inbar, Zvi, Anat, Lazar, Shirley, Shifman, Ohad, Levy, Haim, Gur, David, Laskar, Orly, Beth-Din, Adi

“…High-throughput DNA sequencing (HTS) of pathogens in whole blood samples is hampered by the high host/pathogen nucleic acids ratio. We describe a novel and…”
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Comparative Analysis of the Global Transcriptomic Response to Oxidative Stress of Bacillus anthracis htrA -Disrupted and Parental Wild Type Strains by Zaide, Galia, Elia, Uri, Cohen-Gihon, Inbar, Israeli, Ma'ayan, Rotem, Shahar, Israeli, Ofir, Ehrlich, Sharon, Cohen, Hila, Lazar, Shirley, Beth-Din, Adi, Shafferman, Avigdor, Zvi, Anat, Cohen, Ofer, Chitlaru, Theodor

“…We previously demonstrated that the HtrA (High Temperature Requirement A) protease/chaperone active in the quality control of protein synthesis, represents an…”
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Generation of Yersinia pestis Attenuated Strains by Signature-Tagged Mutagenesis in Search of Novel Vaccine Candidates by FLASHNER, Yehuda, MAMROUD, Emanuelle, VELAN, Baruch, SHAFFERMAN, Avigdor, COHEN, Sara, TIDHAR, T. Avital, BER, Raphael, AFTALION, Moshe, GUR, David, LAZAR, Shirley, ZVI, Anat, BINO, Tamar, ARIEL, Naomi

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge by Yahalom-Ronen, Yfat, Tamir, Hadas, Melamed, Sharon, Politi, Boaz, Shifman, Ohad, Achdout, Hagit, Vitner, Einat B., Israeli, Ofir, Milrot, Elad, Stein, Dana, Cohen-Gihon, Inbar, Lazar, Shlomi, Gutman, Hila, Glinert, Itai, Cherry, Lilach, Vagima, Yaron, Lazar, Shirley, Weiss, Shay, Ben-Shmuel, Amir, Avraham, Roy, Puni, Reut, Lupu, Edith, Bar-David, Elad, Sittner, Assa, Erez, Noam, Zichel, Ran, Mamroud, Emanuelle, Mazor, Ohad, Levy, Haim, Laskar, Orly, Yitzhaki, Shmuel, Shapira, Shmuel C., Zvi, Anat, Beth-Din, Adi, Paran, Nir, Israely, Tomer

“…The COVID-19 pandemic caused by SARS-CoV-2 imposes an urgent need for rapid development of an efficient and cost-effective vaccine, suitable for mass…”
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Monkeypox DNA levels correlate with virus infectivity in clinical samples, Israel, 2022 by Paran, Nir, Yahalom-Ronen, Yfat, Shifman, Ohad, Lazar, Shirley, Ben-Ami, Ronen, Yakubovsky, Michal, Levy, Itzchak, Wieder-Feinsod, Anat, Amit, Sharon, Katzir, Michal, Carmi-Oren, Noga, Levcovich, Ariela, Hershman-Sarafov, Mirit, Paz, Alona, Thomas, Rebecca, Tamir, Hadas, Cherry-Mimran, Lilach, Erez, Noam, Melamed, Sharon, Barlev-Gross, Moria, Karmi, Shay, Politi, Boaz, Achdout, Hagit, Weiss, Shay, Levy, Haim, Schuster, Ofir, Beth-Din, Adi, Israely, Tomer

“…The current monkeypox virus global spread and lack of data regarding clinical specimens' infectivity call for examining virus infectivity, and whether this…”
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Case Report: Imported Melioidosis from Goa, India to Israel, 2018 by Brosh-Nissimov, Tal, Grupel, Daniel, Abuhasira, Shlomi, Leskes, Hanna, Israeli, Ma'ayan, Lazar, Shirley, Elia, Uri, Israeli, Ofir, Beth-Din, Adi, Bar-Haim, Erez, Cohen-Gihon, Inbar, Zvi, Anat, Cohen, Ofer, Chitlaru, Theodor

“…A previously healthy young man presented with a chronic cavitary pulmonary infection that began while in Goa, India. was cultured from sputum samples. The…”
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T cells play an essential role in anti-F1 mediated rapid protection against bubonic plague by Levy, Yinon, Flashner, Yehuda, Tidhar, Avital, Zauberman, Ayelet, Aftalion, Moshe, Lazar, Shirley, Gur, David, Shafferman, Avigdor, Mamroud, Emanuelle

“…Highlights ► Vaccination with rF1 shortly after exposure to Yersinia pestis provides protection. ► Anti-F1 humoral response mediates the rapid onset of…”
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New Spotted Fever Group Rickettsia Isolate, Identified by Sequence Analysis of Conserved Genomic Regions by Klein, Dar, Beth-Din, Adi, Cohen, Regev, Lazar, Shirley, Glinert, Itai, Zayyad, Hiba, Atiya-Nasagi, Yafit

“…The clinical features of spotted fever group (SFG) induced disease range from a mild to severe illness. The clinical complexity is even greater due to the fact…”
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Transcriptome Sequencing Data of Bacillus anthracis Vollum Δ htrA and Its Parental Strain, Isolated under Oxidative Stress by Chitlaru, Theodor, Cohen-Gihon, Inbar, Israeli, Ofir, Elia, Uri, Zaide, Galia, Israeli, Ma'ayan, Beth-Din, Adi, Lazar, Shirley, Ehrlich, Sharon, Zvi, Anat, Cohen, Ofer

“…The high-temperature requirement chaperone/protease (HtrA) is involved in the stress response of the anthrax-causing pathogen Bacillus anthracis . Resilience…”
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