Search Results - "Lazar, Dan"

A live-cell assay for the real-time assessment of extracellular ATP levels by Niles, Andrew L., Cali, James J., Lazar, Dan F.

“…Extracellular ATP (eATP) is a potent damage associated molecular pattern (DAMP) molecule known to exert profound effects on the innate and adaptive immune…”
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Design Procedure and Efficiency Analysis of a 99.3% Efficient 10 kW Three-Phase Three-Level Hybrid GaN/Si Active Neutral Point Clamped Converter by Najjar, Mohammad, Kouchaki, Alireza, Nielsen, Jesper, Dan Lazar, Radu, Nymand, Morten

“…High-efficient and power-dense ac-dc power electronic converters are demanded for a wide range of applications, such as motor drives and active rectifiers. The…”
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Lipid phosphatases as drug discovery targets for type 2 diabetes by Lazar, Dan F, Saltiel, Alan R

“…The soaring incidence of type 2 diabetes has created pressure for new pharmaceutical strategies to treat this devastating disease. With much of the focus on…”
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Multimodal assessment of autophagy in mammalian cells with a novel, LC3-based tandem reporter by Lazar, Dan F, Gillette, Amani A, Lewis, Samantha R, Butler, Braeden L

“…Autophagy is an important intracellular pathway for the degradation of superfluous or harmful subcellular materials, thereby playing a critical role in the…”
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766 Novel bioluminescent bioassays for the discovery and development of T cell redirecting cancer therapies by Ott, Vanessa, Gilden, Julia, Grailer, Jamison, Slater, Michael, Stecha, Pete, Hartnett, Jim, Lazar, Dan, Fan, Frank, Cong, Mei, Cheng, Zhijie Jey

“…BackgroundTwo main approaches for T cell-based therapies involve molecular T cell redirection by CD3 bispecific molecules such as bispecific T-cell engagers…”
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Cluj-Napoca without Students: An Estimation of The Gap in the City’s Economy by Andrei Chircă, Dan Tudor Lazăr

“…In the new context of COVID-19, the authors assess the economic gap of the absence of students from Cluj-Napoca for one month due to the pandemic quarantine…”
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Students’s Visitors – Among the Unexplored Types of Local Tourism? by Chircă, Andrei, Lazăr, Dan Tudor

“…Universities have the capacity to attract students from a vast geographical area, thus resulting in new residences for its host city. This is a well-known…”
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Survey on EU27 Budgets: Taxes by Adrian Mihai INCEU, Paul ZAI, Mihai BABICI, Dan Tudor LAZĂR

“…In this study we make an analysis of the major aspects concerning the budgets of the EU countries. On this paper we focus on the main taxes of the 27 EU…”
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Underground Economy’s Measurement Methods by Dan Tudor LAZĂR, Bogdan Andrei MOLDOVAN, Alexandru PAVEL

“…It is argued that the underground economy is old as government itself. Many people know how the underground economy functions, but a few are those who know its…”
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Homogeneous bioluminescent immunoassays detect profound synergistic regulation of IL-8 and MCP-1 release in cultured human monocytes by Lazar, Dan, Ames, Cassidy, Sequeira, Paula, Kupcho, Kevin, Mamott, Daniel, O'Brien, Martha, Mahan, Sarah, Cali, James

“…Abstract We have developed sensitive bioluminescent immunoassays for IL-8 and MCP-1 and applied these homogeneous assays to demonstrate synergistic regulation…”
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Differential T Cell Responsiveness to Proliferative Stimuli Assessed with a Novel, Homogeneous Ki-67 Immunoassay by Lazar, Dan F, Kupcho, Kevin R., Niles, Andrew L., Cali, James J.

“…Abstract Proliferative capacity is an important component of T cell fitness and a relevant parameter for characterization of CAR T cells and T cell activating…”
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Development of a specific, active human IL-18 assay for assessing inflammasome activation by Mamott, Daniel B, Mahan, Sarah, Cali, Jim, Lazar, Dan, O’Brien, Martha

“…Abstract Interleukin-18 (IL-18) was first identified for its ability to induce interferon-γ expression. IL-18 is a proinflammatory cytokine and its release…”
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Lumit: a novel bioluminescent, homogenous immunoassay platform for analyte detection by Bach, Maggie L, O’Brien, Martha A., Nath, Nidhi, Zegzouti, Hicham, Lazar, Dan, Cali, James

“…Abstract The detection of a specific analyte in a complex mixture by an immunoassay is a common procedure in many bioanalytical workflows. Immunoassays rely on…”
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Detecting IL-1β release with a rapid, homogeneous, bioluminescent immunoassay by O’Brien, Martha A., Lindstedt, Anders, Lazar, Dan, Cali, James

“…Abstract IL-1β is an important inflammatory cytokine of the innate immune system, released from monocytes, macrophages, and other cell types in response to a…”
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Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by Insulin (∗) by Lazar, Dan F., Wiese, Russell J., Brady, Matthew J., Mastick, Cynthia Corley, Waters, Steven B., Yamauchi, Keishi, Pessin, Jeffrey E., Cuatrecasas, Pedro, Saltiel, Alan R.

“…Insulin stimulates the activity of mitogen-activated protein kinase (MAPK) via its upstream activator, MAPK kinase (MEK), a dual specificity kinase that…”
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A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells by O'Brien, Martha, Moehring, Danielle, Muñoz-Planillo, Raúl, Núñez, Gabriel, Callaway, Justin, Ting, Jenny, Scurria, Mike, Ugo, Tim, Bernad, Laurent, Cali, James, Lazar, Dan

“…Inflammasomes are protein complexes induced by diverse inflammatory stimuli that activate caspase-1, resulting in the processing and release of cytokines,…”
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Abstract 1933: Improved DAMP assays for the in vitro assessment of immunogenic cell death by Niles, Andrew L., Kupcho, Kevin R., Lazar, Dan F., Cali, James J.

“…Abstract The extracellular levels of damage-associated molecular patterns (DAMPs) released during immunogenic cell death (ICD) are positively correlated with…”
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Exploring Water Taxation Systems Logo East Project RO05.13 by Adrian Mihai INCEU, Alexandra MUŢIU, Dan Tudor LAZĂR, Codruţa FĂT

“…In the first part of the paper the stages of our researches, the objectives and the methodology are presented. The paper focus on creating an evaluation system…”
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A real-time, bioluminescent annexin V assay for the assessment of apoptosis by Kupcho, Kevin, Shultz, John, Hurst, Robin, Hartnett, Jim, Zhou, Wenhui, Machleidt, Thomas, Grailer, Jamison, Worzella, Tracy, Riss, Terry, Lazar, Dan, Cali, James J., Niles, Andrew

“…Apoptosis is an important and necessary cell death program which promotes homeostasis and organismal survival. When dysregulated, however, it can lead to a…”
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Abstract 1832: A real-time extracellular ATP assay to identify modulators of the innate immune response by Niles, Andrew L., Kupcho, Kevin R., Lazar, Dan F., Cali, James J.

“…Abstract Damage-associated molecular patterns (DAMPs) liberated or exposed by dying cells after chemotherapeutic treatment augment innate immune responses and…”
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