Search Results - "Layzell, Scott"

Prevalence of Borrelia burgdorferi and Borrelia miyamotoi in questing Ixodes ricinus ticks from four sites in the UK by Layzell, Scott J, Bailey, Daniel, Peacey, Mick, Nuttall, Patricia A

“…Borrelia miyamotoi is a spirochete bacterium related to Borrelia burgdorferi sensu lato, the cause of Lyme borreliosis, and vectored by ticks. In 2014, B…”
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NF-κB and Extrinsic Cell Death Pathways – Entwined Do-or-Die Decisions for T cells by Blanchett, Sam, Boal-Carvalho, Ines, Layzell, Scott, Seddon, Benedict

“…NF-κB signaling is required at multiple stages of T cell development and function. The NF-κB pathway integrates signals from many receptors and involves…”
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IKK promotes naïve T cell survival by repressing RIPK1-dependent apoptosis and activating NF-κB by Carty, Fiona, Layzell, Scott, Barbarulo, Alessandro, Islam, Farjana, Webb, Louise V, Seddon, Benedict

“…The inhibitor of κB kinase (IKK) complex regulates the activation of the nuclear factor κB (NF-κB) family of transcription factors. In addition, IKK represses…”
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The Role of Ikk Signalling in T Cells by Layzell, Scott James

“…The Inhibitor of Kappa B Kinase (IKK) complex is a key component of canonical NF-κB signalling. More recently, the IKK complex has emerged as a regulator of…”
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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death by Mannion, Jonathan, Gifford, Valentina, Bellenie, Benjamin, Fernando, Winnie, Ramos Garcia, Laura, Wilson, Rebecca, John, Sidonie Wicky, Udainiya, Savita, Patin, Emmanuel C, Tiu, Crescens, Smith, Angel, Goicoechea, Maria, Craxton, Andrew, Moraes de Vasconcelos, Nathalia, Guppy, Naomi, Cheung, Kwai-Ming J, Cundy, Nicholas J, Pierrat, Olivier, Brennan, Alfie, Roumeliotis, Theodoros I, Benstead-Hume, Graeme, Alexander, John, Muirhead, Gareth, Layzell, Scott, Lyu, Wenxin, Roulstone, Victoria, Allen, Mark, Baldock, Holly, Legrand, Arnaud, Gabel, Florian, Serrano-Aparicio, Natalia, Starling, Chris, Guo, Hongyan, Upton, Jason, Gyrd-Hansen, Mads, MacFarlane, Marion, Seddon, Benedict, Raynaud, Florence, Roxanis, Ioannis, Harrington, Kevin, Haider, Syed, Choudhary, Jyoti S, Hoelder, Swen, Tenev, Tencho, Meier, Pascal

“…Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions as a critical stress sentinel that coordinates cell survival, inflammation, and…”
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NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells by Layzell, By Scott, Barbarulo, Alessandro, van Loo, Geert, Beyaert, Rudi, Seddon, Benedict

“…IKK signalling is essential for survival of thymocytes by repressing RIPK1 induced cell death rather than its canonical function of activating NF-κB. The role…”
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