Search Results - "Layton, D. M."

A statistical analysis of RNA folding algorithms through thermodynamic parameter perturbation by Layton, D. M., Bundschuh, R.

“…Computational RNA secondary structure prediction is rather well established. However, such prediction algorithms always depend on a large number of…”
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Localization of a Gene for Familial Hemophagocytic Lymphohistiocytosis at Chromosome 9q21.3-22 by Homozygosity Mapping by Ohadi, Mina, Lalloz, Michel R.A., Sham, Pak, Zhao, Jinghua, Dearlove, Andrew M., Shiach, Caroline, Kinsey, Sally, Rhodes, Michael, Layton, D. Mark

“…Familial hemophagocytic lymphohistiocytosis (FHL), also known as familial erythrophagocytic lymphohistiocytosis and familial histiocytic reticulosis, is a rare…”
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Quality of reporting of dental survival analyses by Layton, D. M., Clarke, M.

“…Summary To explore the quality of reporting (writing and graphics) of articles that used time‐to‐event analyses to report dental treatment outcomes. A…”
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Characterization of erosion and failure processes of spark plugs after field service in natural gas engines by Lin, H.T., Brady, M.P., Richards, R.K., Layton, D.M.

“…Microstructural and optical spectroscopic analyses were carried out on as-received and used spark plugs after field service in natural gas (NG) reciprocating…”
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Rapid Identification of Hemoglobin Variants by Electrospray Ionization Mass Spectrometry by Wild, B.J., Green, B.N., Cooper, E.K., Lalloz, M.R.A., Erten, S., Stephens, A.D., Layton, D.M.

“…ABSTRACT The precise identification of human hemoglobin variants, over 700 human hemoglobin variants are known, is essential for prediction of their clinical…”
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P1522: LONG‐TERM EFFICACY AND SAFETY OF THE ORAL PYRUVATE KINASE ACTIVATOR MITAPIVAT IN ADULTS WITH NON–TRANSFUSION‐DEPENDENT ALPHA‐ OR BETA‐THALASSEMIA by Kuo, K. H. M., Layton, D. M., Lal, A., Al‐Samkari, H., Bhatia, J., Kosinski, P. A., Tong, B., Lynch, M., Uhlig, K., Vichinsky, E. P.

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Cost satisfaction analysis: a novel patient-based approach for economic analysis of the utility of fixed prosthodontics by WALTON, T. R., LAYTON, D. M.

“…Summary  The aim of this study was to apply a novel economic tool (cost satisfaction analysis) to assess the utility of fixed prosthodontics, to review its…”
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P1562: CHARACTERIZING IRON OVERLOAD BY AGE IN PATIENTS DIAGNOSED WITH PYRUVATE KINASE DEFICIENCY – A DESCRIPTIVE ANALYSIS FROM THE PEAK REGISTRY by Bianchi, P., Grace, R. F., Vives Corrons, J.‐L., Glader, B., Glenthøj, A., Kanno, H., Kuo, K. H., Lander, C., Layton, D. M., Pospíŝilová, D., Viprakasit, V., Williams, J., Yan, Y., McGee, B., Beers, E. J.

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P1548: LONG‐TERM TREATMENT WITH ORAL MITAPIVAT IS ASSOCIATED WITH NORMALIZATION OF HEMOGLOBIN LEVELS IN PATIENTS WITH PYRUVATE KINASE DEFICIENCY by Barcellini, W., Grace, R. F., Al‐Samkari, H., Glenthøj, A., Rothman, J. A., Morado Arias, M., Layton, D. M., Andres, O., DiBacco, M., Hawkins, P., Judge, M. P., Tai, F., Morales‐Arias, J., Beynon, V., Beers, E. J.

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P1544: BONE MINERAL DENSITY REMAINS STABLE IN PYRUVATE KINASE DEFICIENCY PATIENTS RECEIVING LONG‐TERM TREATMENT WITH MITAPIVAT by Al‐Samkari, H., Grace, R. F., Glenthøj, A., Andres, O., Barcellini, W., Galactéros, F., Kuo, K. H. M., Layton, D. M., Morado Arias, M., Viprakasit, V., Dong, Y., Tai, F., Grekas, L., Khoja, K., Gheuens, S., McGee, B., Porter, J. B., Beers, E. J.

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P1545: DURABILITY OF HEMOGLOBIN RESPONSE AND REDUCTION IN TRANSFUSION BURDEN IS MAINTAINED OVER TIME IN PATIENTS WITH PYRUVATE KINASE DEFICIENCY TREATED WITH MITAPIVAT IN A LONG‐TERM EXTENSION STUDY by Grace, R. F., Glenthøj, A., Barcellini, W., Verhovsek, M., Rothman, J. A., Morado Arias, M., Layton, D. M., Andres, O., Galactéros, F., Beers, E. J., Onodera, K., Viprakasit, V., Chonat, S., Porter, J. B., Judge, M. P., Kosinski, P. A., Hawkins, P., Gheuens, S., Xu, R., McGee, B., Beynon, V., Al‐Samkari, H.

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Predominance of the HLA-H Cys282Tyr mutation in Austrian patients with genetic haemochromatosis by Datz, Christian, Lalloz, Michel R.A., Vogel, Wolfgang, Graziadei, Ivo, Hackl, Franz, Vautier, Guy, Layton, D.Mark, Maier-Dobersberger, Theresia, Ferenci, Peter, Penner, Edward, Sandhofer, Friedrich, Bomford, Adrian, Paulweber, Bernhard

“…Background/Aims: Genetic haemochromatosis is the most common autosomal recessive disorder in Northern European populations. A major histocompatibility complex…”
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Molecular analysis of the genotype-phenotype relationship in factor X deficiency by MILLAR, D. S, ELLISTON, L, CACHIA, P, PASI, K. J, LAYTON, D. M, COOPER, D. N, DEEX, P, KRAWCZAK, M, WACEY, A. I, REYNAUD, J, NIEUWENHUIS, H. K, BOLTON-MAGGS, P, MANNUCCI, P. M, REVERTER, J. C

“…Factor X deficiency is a rare haemorrhagic condition, normally inherited as an autosomal recessive trait, in which a variable clinical presentation correlates…”
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A Systematic Review and Meta - Analysis of the Survival of Non - Feldspathic Porcelain Veneers over 5 and 10 Years by Clarke , M, Layton , D. M

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Diagnosis of pyrimidine 5′‐nucleotidase deficiency suspected from a blood film by Al‐Jafar, Hassan A., Layton, D. M., Robertson, Lynn, Escuredo, Emilia, Bain, Barbara J.

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Haemophagocytic lymphohistiocytosis: experience at two U.K. centres by Hirst, W J, Layton, D M, Singh, S, Mieli-Vergani, G, Chessells, J M, Strobel, S, Pritchard, J

“…Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder of inappropriate macrophage activation. Both familial and sporadic forms, which may be…”
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Dominant influence of gamma-globin promoter polymorphisms on fetal haemoglobin expression in sickle cell disease by Ofori-Acquah, S F, Lalloz, M R A, Serjeant, G, Layton, D M

“…Polymorphisms of multiple cis-acting elements in the beta-globin locus are associated with variable fetal haemoglobin (HbF) level in sickle cell disease. We…”
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Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia by Tobal, K, Pagliuca, A, Bhatt, B, Bailey, N, Layton, D M, Mufti, G J

“…We studied 41 patients with myelodysplastic syndromes or acute myeloid leukemia to assess the presence of point mutations in the human FMS gene (M-CSF…”
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RESULTS FROM A PHASE 2 STUDY OF MITAPIVAT IN ADULTS WITH NON–TRANSFUSION-DEPENDENT ALPHA- OR BETA-THALASSEMIA by KH Kuo, DM Layton, A Lal, H Al-Samkari, J Bhatia, B Tong, M Lynch, K Uhlig, EP Vichinsky

“…Objectives: Thalassemias are characterized by ineffective erythropoiesis and hemolysis due to imbalanced production and precipitation of globin chains…”
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Ancestral origin of variation in the triosephosphate isomerase gene promoter by HUMPHRIES, A, ATIONU, A, LALLOZ, M. R. A, LAYTON, D. M

“…A high frequency of nucleotide substitutions -5A/G, -8G/A, -24T/G in the triosephosphate isomerase (TPI) gene promoter has been demonstrated in…”
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