Search Results - "Laychock, Suzanne G"

Protein Kinase C and Calcium Regulation of Adenylyl Cyclase in Isolated Rat Pancreatic Islets by YINGRAO TIAN, LAYCHOCK, Suzanne G

“…Protein Kinase C and Calcium Regulation of Adenylyl Cyclase in Isolated Rat Pancreatic Islets Yingrao Tian and Suzanne G. Laychock Department of Pharmacology…”
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Endothelial Differentiation Gene Receptors in Pancreatic Islets and INS-1 Cells by LAYCHOCK, Suzanne G, YINGRAO TIAN, SESSANNA, Shawn M

“…Endothelial Differentiation Gene Receptors in Pancreatic Islets and INS-1 Cells Suzanne G. Laychock , Yingrao Tian and Shawn M. Sessanna From the Department of…”
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Atrial Natriuretic Peptide Promotes Pancreatic Islet β-Cell Growth and Akt/Foxo1a/Cyclin D2 Signaling by You, Hui, Laychock, Suzanne G

“…The adult differentiated insulin-secreting pancreatic islet β-cell experiences slow growth. This study shows that atrial natriuretic peptide (ANP) stimulates…”
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Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets by You, Hui, Laychock, Suzanne G

“…Atrial natriuretic peptide (ANP) levels correlate with hyperglycemia in diabetes mellitus, but ANP effects on pancreatic islet β-cell insulin secretion are…”
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Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion by Lock, Lye T., Laychock, Suzanne G., Tzanakakis, Emmanuel S.

“…Cells from primary islets and beta-cell lines form pseudoislets (PIs) in static cultures. Interestingly, MIN6 beta-cells with aberrant regulation of…”
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1052 D-Amino Acids as a Novel Link between Gut Microbiota and Non-Alcoholic Fatty Liver Disease by Liu, Wensheng, Baker, Susan S, Arbizu, Ricardo A, Jackson, Aswad, Baker, Robert D, Laychock, Suzanne G, Zhu, Lixin

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Sphingosine 1-Phosphate Affects Cytokine-Induced Apoptosis in Rat Pancreatic Islet β-Cells by Laychock, Suzanne G, Sessanna, Shawn M, Lin, Mei-Hui, Mastrandrea, Lucy D

“…Cytokines mediate pancreatic islet β-cell apoptosis and necrosis, leading to loss of insulin secretory capacity and type 1 diabetes mellitus. The cytokines,…”
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Inositol 1,4,5-trisphosphate receptor isoform expression in mouse pancreatic islets: effects of carbachol by Lee, Bumsup, Laychock, Suzanne G.

“…1 The inositol 1,4,5-trisphosphate receptors (IP3Rs) are ligand-gated Ca 2+ channels that regulate intracellular Ca 2+ mobilization. Among the IP3R mRNA…”
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Regulated Insulin Delivery From Human Epidermal Cells Reverses Hyperglycemia by Tian, Jun, Lei, Pedro, Laychock, Suzanne G, Andreadis, Stelios T

“…Alternative insulin therapies are being sought that will provide euglycemic control for people with diabetes mellitus. The epidermis is a self-renewing tissue…”
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Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells : Response to cytokines by MASTRANDREA, Lucy D, SESSANNA, Shawn M, LAYCHOCK, Suzanne G

“…Sphingosine-1 phosphate (S1P) is a bioactive sphingolipid with the potential to mobilize Ca2+, to inhibit apoptosis, and to promote mitogenesis. Sphingosine…”
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Proteasomal Activation Mediates Down-Regulation of Inositol 1,4,5-Trisphosphate Receptor and Calcium Mobilization in Rat Pancreatic Islets by Lee, Bumsup, Gai, Wenlin, Laychock, Suzanne G.

“…Abstract Inositol 1,4,5-trisphosphate receptor (IP3R) protein levels in isolated rat pancreatic islets were investigated in response to carbachol (CCh) and…”
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Prolactin regulates adenylyl cyclase and insulin secretion in rat pancreatic islets by Tian, Yingrao, Laychock, Suzanne G.

“…A role for prolactin (PRL) in the regulation of adenylyl cyclase (AC), cyclic AMP (cAMP) formation and insulin secretion was studied in isolated rat pancreatic…”
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Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic Islets and INS-1 Cells by Mastrandrea, Lucy D., Sessanna, Shawn M., Laychock, Suzanne G.

“…Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic Islets and INS-1 Cells Response to Cytokines Lucy D. Mastrandrea 1 2 ,…”
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Glucose Regulates Expression of Inositol 1,4,5-Trisphosphate Receptor Isoforms in Isolated Rat Pancreatic Islets by Lee, Bumsup, Jonas, Jean-Christophe, Weir, Gordon C., Laychock, Suzanne G.

“…Abstract Isolated rat pancreatic islets were studied to determine the dynamic regulatory effects of glucose stimulation on the expression of messenger RNA…”
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dietary intervention (high carbohydrate) during the neonatal period causes islet dysfunction in rats by Aalinkeel, R, Srinivasan, M, Kalhan, S.C, Laychock, S.G, Patel, M.S

“…Artificial rearing of 4-day-old rat pups on a high-carbohydrate (HC) milk formula results in the immediate onset of hyperinsulinemia. To evaluate these early…”
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Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula by Srinivasan, M, Aalinkeel, R, Song, F, Lee, B, Laychock, S G, Patel, M S

“…Artificial rearing of neonatal rats on a high-carbohydrate (HC) milk formula resulted in the immediate onset of hyperinsulinemia. This study examines, in…”
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Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: implications for treatment of diabetes by Lei, Pedro, Ogunade, Adebimpe, Kirkwood, Keith L, Laychock, Suzanne G, Andreadis, Stelios T

“…Despite many years of research, daily insulin injections remain the gold standard for diabetes treatment. Gene therapy may provide an alternative strategy by…”
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Regulation of Inositol Trisphosphate Receptor Isoform Expression in Glucose-Desensitized Rat Pancreatic Islets: Role of Cyclic Adenosine 3′,5′-Monophosphate and Calcium by Lee, Bumsup, Laychock, Suzanne G.

“…Abstract The regulation of inositol 1,4,5-trisphosphate receptor (IP3R) messenger RNA (mRNA) and protein expression was investigated in glucose-desensitized…”
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Rat Pancreatic Islet and RINm5F Cell Responses to Epiandrosterone, Dehydroepiandrosterone and Interleukin-1β by Laychock, Suzanne G

“…Epiandrosterone (EA), dehydroepiandrosterone (DHEA), and their sulfate (-S) and acetate (-A) conjugates were investigated for effects on isolated pancreatic…”
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Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum by Takeuchi, Takashi, Aletta, John M, Laychock, Suzanne G, Tian, Yingrao, Rubin, Ronald P

“…The present study was undertaken to examine the factors that regulate rat serum (RS)- and nerve growth factor (NGF)-induced differentiation in a rat parotid…”
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