Search Results - "Lay, Margarita"
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BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design
Published in Frontiers in immunology (29-11-2019)“…The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the ability to induce non-specific cross-protection against pathogens…”
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Human Norovirus Proteins: Implications in the Replicative Cycle, Pathogenesis, and the Host Immune Response
Published in Frontiers in immunology (16-06-2020)“…Human noroviruses (HuNoVs) are the cause of more than 95% of epidemic non-bacterial gastroenteritis worldwide, with some lethal cases. These viral agents…”
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Host Components Contributing to Respiratory Syncytial Virus Pathogenesis
Published in Frontiers in immunology (12-09-2019)“…Respiratory syncytial virus (RSV) is the most prevalent viral etiological agent of acute respiratory tract infection. Although RSV affects people of all ages,…”
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Replication of Human Norovirus RNA in Mammalian Cells Reveals Lack of Interferon Response
Published in Journal of virology (01-10-2016)“…Human noroviruses (HuNoVs), named after the prototype strain Norwalk virus (NV), are a leading cause of acute gastroenteritis outbreaks worldwide. Studies on…”
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New insights into the pathogenesis of SARS-CoV-2 during and after the COVID-19 pandemic
Published in Frontiers in immunology (07-06-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the respiratory distress condition known as COVID-19. This disease broadly…”
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Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection
Published in The Journal of immunology (1950) (01-07-2017)“…Human respiratory syncytial virus (hRSV) is the leading cause of severe lower respiratory tract infections in children. The development of novel prophylactic…”
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Human Metapneumovirus: Mechanisms and Molecular Targets Used by the Virus to Avoid the Immune System
Published in Frontiers in immunology (24-10-2018)“…Human metapneumovirus (hMPV) is a respiratory virus, first reported the year 2001. Since then, it has been described as one of the main etiological agents that…”
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Lack of norovirus replication and histo-blood group antigen expression in 3-dimensional intestinal epithelial cells
Published in Emerging infectious diseases (01-03-2013)“…Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide. An in vitro model for NoV replication remains elusive, making study of the virus…”
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Elevated IL-3 and IL-12p40 levels in the lower airway of infants with RSV-induced bronchiolitis correlate with recurrent wheezing
Published in Cytokine (Philadelphia, Pa.) (01-12-2015)“…•Possible role of cytokines and chemokines in the lung pathology caused by RSV.•High levels of Th2 and pro-inflammatory mediators in infants with RSV…”
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Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection
Published in Frontiers in cellular and infection microbiology (26-09-2022)“…Streptococcus pneumoniae is a Gram-positive bacterium and the leading cause of bacterial pneumonia in children and the elderly worldwide. Currently, two types…”
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Human metapneumovirus infection activates the TSLP pathway that drives excessive pulmonary inflammation and viral replication in mice
Published in European journal of immunology (01-06-2015)“…Human metapneumovirus (hMPV) is a leading cause of acute respiratory tract infections in children and the elderly. The mechanism by which this virus triggers…”
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STAT1-Dependent Innate Immunity to a Norwalk-like Virus
Published in Science (American Association for the Advancement of Science) (07-03-2003)“…Norwalk-like caliciviruses (Noroviruses) cause over 90% of nonbacterial epidemic gastroenteritis worldwide, but the pathogenesis of norovirus infection is…”
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Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution
Published in Frontiers in immunology (18-01-2018)“…Vaccines have significantly reduced the detrimental effects of numerous human infectious diseases worldwide, helped to reduce drastically child mortality rates…”
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New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus
Published in Critical reviews in microbiology (02-09-2016)“…The respiratory syncytial virus (RSV) is the most prevalent etiological agent of lower respiratory tract infections and the first cause of hospitalization in…”
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Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans
Published in Virology (New York, N.Y.) (10-10-2010)“…Abstract Human noroviruses are difficult to study due to the lack of an efficient in vitro cell culture system or small animal model. Murine norovirus…”
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Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity
Published in Frontiers in cellular and infection microbiology (16-08-2017)“…The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in…”
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Inflammatory damage on respiratory and nervous systems due to hRSV infection
Published in Current opinion in immunology (01-10-2015)“…Highlights • We discuss about how interferons contribute at controlling viral infection. • We discuss the role of IL-17 in lungs damage due to hRSV infection…”
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Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response
Published in Microbes and infection (01-03-2013)“…This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication…”
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Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection
Published in Virulence (18-08-2017)“…Human Respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are the two major etiological viral agents of lower respiratory tract diseases,…”
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Presence of Wild-Type and Attenuated Salmonella enterica Strains in Brain Tissues following Inoculation of Mice by Different Routes
Published in Infection and Immunity (01-07-2008)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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