Search Results - "Laxton, C. D."

Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response by Paterson, Morris, Laxton, Carl D., Thomas, Howard C., Ackrill, Andrew M., Foster, Graham R.

“…Background & Aims: Patients with chronic hepatitis C virus infection are commonly treated with interferon alfa (IFN-α), but the long-term response rate is…”
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Expression and characterization of the hepatitis G virus helicase by Laxton, C. D., McMillan, D., Ackrill, V. Sullivan & A. M.

“…The hepatitis G virus (HGV) is a new member of the Flaviviridae family and has a genomic organization similar to that of hepatitis C virus (HCV). Protein…”
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Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene by Ackrill, A M, Foster, G R, Laxton, C D, Flavell, D M, Stark, G R, Kerr, I M

“…Expression of the E1A oncogene of adenovirus type 5 inhibits the response of interferon (IFN)-inducible constructs to Type I (alpha,beta) and II (gamma) IFNs…”
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Functional differences in the promoters of the interferon‐inducible (2′‐5′)A oligoadenylate synthetase and 6–16 genes in interferon‐resistant Daudi cells by GUILLE, Matthew J., LAXTON, Carl D., RUTHERFORD, Michael N., WILLIAMS, Bryan R. G., KERR, Ian M.

“…A clone of interferon‐α‐resistant (IFNr) Daudi cells retained much greater transcriptional inducibility of the (2′–5′) oligoadenylate synthetase than the 6–16…”
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Inhibition of the cellular response to interferon by products of the adenovirus type 5 E1A oncogene by ACKRILL, A. M, FOSTER, G. R, LAXTON, C. D, FLAVELL, D. M, STARK, G. R, KERR, M

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Functional differences in the promoters of the interferon-inducible (2'-5')A oligoadenylate syntethase and 6-16 genes in interferon-resistant Daudi cells by GUILLE, M. J, LAXTON, C. D, RUTHERFORD, M. N, WILLIAMS, B. R. G, KERR, I. M

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