Search Results - "Laxton, C"

Treatment of obstetric post-dural puncture headache. Part 2: epidural blood patch by Russell, R., Laxton, C., Lucas, D.N., Niewiarowski, J., Scrutton, M., Stocks, G.

“…•Postnatal headache may be associated with maternal mortality.•The management of obstetric post-dural puncture headache (PDPH) varies considerably.•Much of the…”
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Antenatal and Postnatal Analgesia: Scientific Impact Paper No. 59 by Bisson, D L, Newell, S D, Laxton, C

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Treatment of obstetric post-dural puncture headache. Part 1: conservative and pharmacological management by Russell, R., Laxton, C., Lucas, D.N., Niewiarowski, J., Scrutton, M., Stocks, G.

“…•Postnatal headache may be associated with maternal mortality.•The management of obstetric post-dural puncture headache (PDPH) varies considerably.•Much of the…”
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Advanced Glycation End-Product of Low Density Lipoprotein Activates the Toll-Like 4 Receptor Pathway Implications for Diabetic Atherosclerosis by Hodgkinson, Conrad P, Laxton, Ross C, Patel, Kunal, Ye, Shu

“…OBJECTIVE—Diabetes is a major risk factor for coronary heart disease. Accumulation of advanced glycation end-products (AGEs) attributable to hyperglycemia in…”
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Prophylactic use of oxytocin at caesarean section: where are the guidelines? by Weale, N., Laxton, C.

“…The findings of a UK-wide survey into the administration of oxytocin, published in this issue of the Journal, highlight continued variation in practice…”
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A Role of Matrix Metalloproteinase-8 in Atherosclerosis by Laxton, Ross C, Hu, Yanhua, Duchene, Johan, Zhang, Feng, Zhang, Zhongyi, Leung, Kit-Yi, Xiao, Qingzhong, Scotland, Ramona S, Hodgkinson, Conrad P, Smith, Katherine, Willeit, Johann, López-Otín, Carlos, Simpson, Iain A, Kiechl, Stefan, Ahluwalia, Amrita, Xu, Qingbo, Ye, Shu

“…RATIONALE:Atherosclerotic lesions express matrix metalloproteinase (MMP)8, which possesses proteolytic activity on matrix proteins particularly fibrillar…”
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Choice of anaesthetic agents for caesarean section: A UK survey of current practice by Murdoch, H, Scrutton, M, Laxton, C.H

“…Abstract Background A national survey of current practice and preferred drug choices for both induction and maintenance of general anaesthesia for caesarean…”
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The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF‐4878691) by Fidock, MD, Souberbielle, BE, Laxton, C, Rawal, J, Delpuech‐Adams, O, Corey, TP, Colman, P, Kumar, V, Cheng, JB, Wright, K, Srinivasan, S, Rana, K, Craig, C, Horscroft, N, Perros, M, Westby, M, Webster, R, Ryst, E

“…Hepatitis C virus (HCV) infection is an issue of global concern, and studies are ongoing to identify new therapies that are both effective and safe. PF‐4878691…”
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Quality improvement demands quality measurement by Draycott, T, Sibanda, T, Laxton, C, Winter, C, Mahmood, T, Fox, R

“…Please cite this paper as: Draycott T, Sibanda T, Laxton C, Winter C, Mahmood T, Fox R. Quality improvement demands quality measurement. BJOG…”
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A clinical evaluation of four non‐Luer spinal needle and syringe systems by Kinsella, S. M., Goswami, A., Laxton, C., Kirkham, L., Wharton, N., Bowen, M.

“…Summary We performed an evaluation of non‐Luer spinal devices supplied by four manufacturers or suppliers: Polymedic; Pajunk; Sarstedt; and Smiths. For each…”
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Remifentanil by patient-controlled analgesia compared with intramuscular meperidine for pain relief in labour by Thurlow, J.A., Laxton, C.H., Dick, A., Waterhouse, P., Sherman, L., Goodman, N.W.

“…The pharmacokinetics of remifentanil suggests that it may be suitable for analgesia during labour. In an open pilot study, 36 women requesting meperidine for…”
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Common Variant on Chromosome 9p21 Predicts Severity of Coronary Artery Disease by Chan, Kenneth, MPharm, Motterle, Anna, MSc, Laxton, Ross C., BSc, Ye, Shu, MD, PhD

“…[...]the results of our study support that there is an association between 9p21 and CAD severity, arguing for the notion that the 9p21 variant predisposes to…”
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Primary glioblastoma with oligodendroglial differentiation has better clinical outcome but no difference in common biological markers compared with other types of glioblastoma by Laxton, Ross C, Popov, Sergey, Doey, Lawrence, Jury, Alexa, Bhangoo, Ranj, Gullan, Richard, Chandler, Chris, Brazil, Lucy, Sadler, Gill, Beaney, Ron, Sibtain, Naomi, King, Andrew, Bodi, Istvan, Jones, Chris, Ashkan, Keyoumars, Al-Sarraj, Safa

“…Glioblastoma multiforme with an oligodendroglial component (GBMO) has been recognized in the World Health Organization classification-however, the diagnostic…”
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Use of LMA following failed intubation and CMACE by Hurford, D., Streets, C., Laxton, C.

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Developing a mobile learning solution for health and social care practice by Taylor, J.D., Dearnley, C.A., Laxton, J.C., Coates, C.A., Treasure-Jones, T., Campbell, R., Hall, I.

“…In this article we share our experiences of a large-scale five-year innovative programme to introduce mobile learning into health and social care (H&SC)…”
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Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways by Müller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J.E., Stark, G.R., Kerr, I.M.

“…Mutants in complementation group U3, completely defective in the response of all genes tested to interferons (IFNs) alpha and gamma, do not express the 91 and…”
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Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response by Paterson, Morris, Laxton, Carl D., Thomas, Howard C., Ackrill, Andrew M., Foster, Graham R.

“…Background & Aims: Patients with chronic hepatitis C virus infection are commonly treated with interferon alfa (IFN-α), but the long-term response rate is…”
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Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients by Kyriakou, Theodosios, Pontefract, David E., Viturro, Enrique, Hodgkinson, Conrad P., Laxton, Ross C., Bogari, Neda, Cooper, George, Davies, Michael, Giblett, Joel, Day, Ian N.M., Simpson, Iain A., Albrecht, Christiane, Ye, Shu

“…ATP-binding-cassette-transporter-A1 (ABCA1) plays a pivotal role in intracellular cholesterol removal, exerting a protective effect against atherosclerosis…”
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Where is T5? A survey of anaesthetists by Congreve, K., Gardner, I., Laxton, C., Scrutton, M.

“…Summary The extent of a regional block for Caesarean section must be tested and documented before surgery commences. In recent years a block to ‘touch’ that…”
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Haplotype Effects on Matrix Metalloproteinase-1 Gene Promoter Activity in Cancer Cells by Pearce, Eve G, Laxton, Ross C, Pereira, Andresa C, Ye, Shu

“…Increased expression of matrix metalloproteinase-1 (MMP1) is associated with poor prognosis in cancers. Several single nucleotide polymorphisms (−1607GG>G,…”
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