Search Results - "Laxer, R. M."

Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO by Ramanan, A V, Hampson, L V, Lythgoe, H, Jones, A P, Hardwick, B, Hind, H, Jacobs, B, Vasileiou, D, Wadsworth, I, Ambrose, N, Davidson, J, Ferguson, P J, Herlin, T, Kavirayani, A, Killeen, O G, Compeyrot-Lacassagne, S, Laxer, R M, Roderick, M, Swart, J F, Hedrich, C M, Beresford, M W

“…Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder primarily affecting children and adolescents. It can lead to chronic pain,…”
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Relapse after systemic treatment in paediatric morphoea by Mirsky, L., Chakkittakandiyil, A., Laxer, R.M., O'Brien, C., Pope, E.

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Tumour necrosis factor α inhibitors in the treatment of childhood uveitis by Saurenmann, R. K., Levin, A. V., Rose, J. B., Parker, S., Rabinovitch, T., Tyrrell, P. N., Feldman, B. M., Laxer, R. M., Schneider, R., Silverman, E. D.

“…Objective. To describe the efficacy of anti-TNF-α agents in the treatment of childhood uveitis. Methods. We performed a retrospective chart review of all…”
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Comparison of clinical and radiographic severity of juvenile-onset versus adult-onset ankylosing spondylitis by O'Shea, F D, Boyle, E, Riarh, R, Tse, S M, Laxer, R M, Inman, R D

“…An important unresolved issue in the pathogenesis and clinical course of ankylosing spondylitis (AS) is whether juvenile-onset AS (JoAS) is a clinical entity…”
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Clinical features and outcome of pediatric Wegener's granulomatosis by Akikusa, J. D., Schneider, R., Harvey, E. A., Hebert, D., Thorner, P. S., Laxer, R. M., Silverman, E. D.

“…Objective Wegener's granulomatosis (WG) is a predominantly small‐vessel vasculitis associated with antineutrophil cytoplasmic antibodies (ANCAs). There are few…”
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Increased anticardiolipin antibody IgG titers do not predict recurrent stroke or TIA in children by LANTHIER, S, KIRKHAM, F. J, DEVEBER, G, MITCHELL, L. G, LAXER, R. M, ATENAFU, E, MALE, C, PRENGLER, M, DOMI, T, CHAN, A. K. C, LIESNER, R

“…Increased anticardiolipin antibody (ACLA) immunoglobulin (Ig) G titers are commonly found in children with arterial ischemic stroke (AIS) or TIA (AIS/TIA). The…”
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A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network by Szauter, K.M., Ordas, A., Laxer, R.M., Pope, E., Wherrett, D., Alman, B., Mink, M., Boyd, C.D., Csiszar, K., Hinek, A.

“…Summary Clinical evaluation of a young woman with subcutaneous fibrotic nodules, progressive distal joint contractures and marfanoid stature revealed a…”
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Children with facial morphoea managing everyday life: a qualitative study by Stasiulis, E., Gladstone, B., Boydell, K., O'Brien, C., Pope, E., Laxer, R. M.

“…Summary Background Facial morphoea is a chronic inflammatory skin disorder, typically presenting in childhood and adolescence, which can be disfiguring, and…”
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Methotrexate and corticosteroid therapy for pediatric localized scleroderma by Uziel, Yosef, Feldman, Brian M, Krafchik, Bernice R, Yeung, Rae S.M, Laxer, Ronald M

“…Introduction: Localized scleroderma (LS) can cause permanent disability, and there is no universally accepted effective treatment. Methotrexate (MTX) has been…”
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Gathering expert consensus to inform a proposed trial in chronic nonbacterial osteomyelitis (CNO) by Hedrich, C.M., Beresford, M.W., Dedeoglu, F., Hahn, G., Hofmann, S.R., Jansson, A.F., Laxer, R.M., Miettunen, P., Morbach, H., Pain, C.E., Ramanan, A.V., Roberts, E., Schnabel, A., Theos, A., Whitty, L., Zhao, Y., Ferguson, P.J., Girschick, H.J.

“…Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease that primarily affects children and adolescents. CNO is associated with pain, bone…”
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Children with facial morphoea managing everyday life by Stasiulis, E., Gladstone, B., Boydell, K., O'Brien, C., Pope, E., Laxer, R. M.

“…Summary Facial morphea is a rare chronic inflammatory skin disorder that occurs on the face and can be disfiguring. It typically appears in childhood and…”
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Intravenous immunoglobulin therapy for juvenile dermatomyositis: efficacy and safety by Al-Mayouf, S M, Laxer, R M, Schneider, R, Silverman, E D, Feldman, B M

“…To assess the efficacy of intravenous immunoglobulin (IVIG) for the treatment of juvenile dermatomyositis (JDM) in patients who were unresponsive to…”
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Tubulointerstitial nephritis and uveitis in children and adolescents : Four new cases and a review of the literature by VOHRA, S, EDDY, A, LEVIN, A. V, TAYLOR, G, LAXER, R. M

“…We identified 35 cases of tubulointerstitial nephritis and uveitis (TINU), 31 from a MEDLINE search (1966-1996) of the English literature and 4 from our…”
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Sleep and fatigue and the relationship to pain, disease activity and quality of life in juvenile idiopathic arthritis and juvenile dermatomyositis by Butbul Aviel, Yonatan, Stremler, Robyn, Benseler, Susanne M., Cameron, Bonnie, Laxer, Ronald M., Ota, Sylvia, Schneider, Rayfel, Spiegel, Lynn, Stinson, Jennifer N., Tse, Shirley M. L., Feldman, Brian M.

“…Objectives. To determine and compare the prevalence of disturbed sleep in JIA and JDM and the relationship of sleep disturbance to pain, function, disease…”
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The arthritis of inflammatory childhood myositis syndromes by TSE, Shirley, LUBELSKY, Sari, GORDON, Maggie, AL MAYOUF, Sulaiman M, BABYN, Paul S, LAXER, Ronald M, SILVERMAN, Earl D, SCHNEIDER, Rayfel, FELDMAN, Brian M

“…OBJECTIVE: Arthritis has been an associated finding in juvenile dermatomyositis (JDM), but its prevalence, course, and response to therapy has not been well…”
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Assessment of myocardial perfusion and function in childhood systemic lupus erythematosus by Gazarian, Madlen, Feldman, Brian M., Benson, Lee N., Gilday, David L., Laxer, Ronald M., Silverman, Earl D.

“…Objectives: To determine the prevalence of abnormalities in myocardial perfusion or function in children with systemic lupus erythematosus (SLE), and describe…”
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Measuring disability in juvenile dermatomyositis: validity of the childhood health assessment questionnaire by Feldman, B M, Ayling-Campos, A, Luy, L, Stevens, D, Silverman, E D, Laxer, R M

“…Physical disability is perhaps the most important outcome of juvenile dermatomyositis (JDM). No functional assessment tool has been validated for inflammatory…”
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Long-term toxicity of immune suppression in juvenile rheumatic diseases by LAXER, R. M

“…Although there are not many studies which have addressed long-term outcomes in children with rheumatic disease treated with immunosuppressive agents, the data…”
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Clinical relevance of the risk factors for coronary artery inflammation in Kawasaki disease by Honkanen, V E A, McCrindle, B W, Laxer, R M, Feldman, B M, Schneider, R, Silverman, E D

“…The objective of this study was to determine predictive factors in children with Kawasaki disease (KD) with which we could distinguish the patients with KD who…”
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Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: A long‐term followup study by Saurenmann, R. K., Levin, A. V., Feldman, B. M., Rose, J. B., Laxer, R. M., Schneider, R., Silverman, E. D.

“…Objective To assess the prevalence, risk factors, and long‐term outcome of uveitis in patients with juvenile idiopathic arthritis (JIA). Methods An inception…”
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