Search Results - "Lawyer, Phillip G."

A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates by Oliveira, Fabiano, Rowton, Edgar, Aslan, Hamide, Gomes, Regis, Castrovinci, Philip A, Alvarenga, Patricia H, Abdeladhim, Maha, Teixeira, Clarissa, Meneses, Claudio, Kleeman, Lindsey T, Guimarães-Costa, Anderson B, Rowland, Tobin E, Gilmore, Dana, Doumbia, Seydou, Reed, Steven G, Lawyer, Phillip G, Andersen, John F, Kamhawi, Shaden, Valenzuela, Jesus G

“…Currently, there are no commercially available human vaccines against leishmaniasis. In rodents, cellular immunity to salivary proteins of sand fly vectors is…”
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Chronic parasitic infection maintains high frequencies of short-lived Ly6C+CD4+ effector T cells that are required for protection against re-infection by Peters, Nathan C, Pagán, Antonio J, Lawyer, Phillip G, Hand, Timothy W, Henrique Roma, Eric, Stamper, Lisa W, Romano, Audrey, Sacks, David L

“…In contrast to the ability of long-lived CD8(+) memory T cells to mediate protection against systemic viral infections, the relationship between CD4(+) T cell…”
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Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis Sand Flies (Diptera: Psychodidae) by Bartonella bacilliformis, the Etiologic Agent of Carrión's Disease by Battisti, James M, Lawyer, Phillip G, Minnick, Michael F

“…Bartonella bacilliformis is a pathogenic bacterium transmitted to humans presumably by bites of phlebotomine sand flies, infection with which results in a…”
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Immunity to distinct sand fly salivary proteins primes the anti-Leishmania immune response towards protection or exacerbation of disease by Oliveira, Fabiano, Lawyer, Phillip G, Kamhawi, Shaden, Valenzuela, Jesus G

“…Leishmania parasites are transmitted in the presence of sand fly saliva. Together with the parasite, the sand fly injects biologically active salivary…”
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A Role for Insect Galectins in Parasite Survival by Kamhawi, Shaden, Ramalho-Ortigao, Marcelo, Van M. Pham, Kumar, Sanjeev, Lawyer, Phillip G., Turco, Salvatore J., Barillas-Mury, Carolina, Sacks, David L., Valenzuela, Jesus G.

“…Insect galectins are associated with embryonic development or immunity against pathogens. Here, we show that they can be exploited by parasites for survival in…”
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Oroya fever and verruga peruana: bartonelloses unique to South America by Minnick, Michael F, Anderson, Burt E, Lima, Amorce, Battisti, James M, Lawyer, Phillip G, Birtles, Richard J

“…Bartonella bacilliformis is the bacterial agent of Carrión's disease and is presumed to be transmitted between humans by phlebotomine sand flies. Carrión's…”
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Incrimination of Phlebotomus kandelakii and Phlebotomus balcanicus as vectors of Leishmania infantum in Tbilisi, Georgia by Giorgobiani, Ekaterina, Lawyer, Phillip G, Babuadze, Giorgi, Dolidze, Nato, Jochim, Ryan C, Tskhvaradze, Lamzira, Kikaleishvili, Konstantin, Kamhawi, Shaden

“…A survey of potential vector sand flies was conducted in the neighboring suburban communities of Vake and Mtatsminda districts in an active focus of visceral…”
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High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya) by Kato, Hirotomo, Anderson, Jennifer M, Kamhawi, Shaden, Oliveira, Fabiano, Lawyer, Phillip G, Pham, Van My, Sangare, Constance Souko, Samake, Sibiry, Sissoko, Ibrahim, Garfield, Mark, Sigutova, Lucie, Volf, Petr, Doumbia, Seydou, Valenzuela, Jesus G

“…Salivary proteins from sandflies are potential targets for exploitation as vaccines to control Leishmania infection; in this work we tested the hypothesis that…”
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Infection parameters in the sand fly vector that predict transmission of Leishmania major by Stamper, Lisa W, Patrick, Rachel L, Fay, Michael P, Lawyer, Phillip G, Elnaiem, Dia-Eldin A, Secundino, Nagila, Debrabant, Alain, Sacks, David L, Peters, Nathan C

“…To identify parameters of Leishmania infection within a population of infected sand flies that reliably predict subsequent transmission to the mammalian host,…”
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KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. major transmitted by its natural vector Phlebotomus duboscqi by Gomes, Regis, Teixeira, Clarissa, Oliveira, Fabiano, Lawyer, Phillip G, Elnaiem, Dia-Eldin, Meneses, Claudio, Goto, Yasuyuki, Bhatia, Ajay, Howard, Randall F, Reed, Steven G, Valenzuela, Jesus G, Kamhawi, Shaden

“…Recombinant KSAC and L110f are promising Leishmania vaccine candidates. Both antigens formulated in stable emulsions (SE) with the natural TLR4 agonist MPL®…”
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Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania-major-infected sandflies by Ramalho-Ortigão, Marcelo, Jochim, Ryan C, Anderson, Jennifer M, Lawyer, Phillip G, Pham, Van-My, Kamhawi, Shaden, Valenzuela, Jesus G

“…In sandflies, the blood meal is responsible for the induction of several physiologic processes that culminate in egg development and maturation. During blood…”
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Seasonality and prevalence of Leishmania major infection in Phlebotomus duboscqi Neveu-Lemaire from two neighboring villages in central Mali by Anderson, Jennifer M, Samake, Sibiry, Jaramillo-Gutierrez, Giovanna, Sissoko, Ibrahim, Coulibaly, Cheick A, Traoré, Bourama, Soucko, Constance, Guindo, Boubacar, Diarra, Dansine, Fay, Michael P, Lawyer, Phillip G, Doumbia, Seydou, Valenzuela, Jesus G, Kamhawi, Shaden

“…Phlebotomus duboscqi is the principle vector of Leishmania major, the causative agent of cutaneous leishmaniasis (CL), in West Africa and is the suspected…”
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Identification and characterization of a salivary adenosine deaminase from the sand fly Phlebotomus duboscqi, the vector of Leishmania major in sub-Saharan Africa by Kato, Hirotomo, Jochim, Ryan C, Lawyer, Phillip G, Valenzuela, Jesus G

“…Two transcripts coding for an adenosine deaminase (ADA) were identified by sequencing a Phlebotomus duboscqi salivary gland cDNA library. Adenosine deaminase…”
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Evaluation of recombinant Leishmania polyprotein plus glucopyranosyl lipid A stable emulsion vaccines against sand fly-transmitted Leishmania major in C57BL/6 mice by Peters, Nathan C, Bertholet, Sylvie, Lawyer, Phillip G, Charmoy, Melanie, Romano, Audrey, Ribeiro-Gomes, Flavia L, Stamper, Lisa W, Sacks, David L

“…Numerous experimental Leishmania vaccines have been developed to prevent the visceral and cutaneous forms of Leishmaniasis, which occur after exposure to the…”
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Assessing Insecticide Susceptibility of Laboratory Lutzomyia longipalpis and Phlebotomus papatasi Sand Flies (Diptera: Psychodidae: Phlebotominae) by Denlinger, David S., Lozano-Fuentes, Saul, Lawyer, Phillip G., Black, William C., Bernhardt, Scott A.

“…Chemical insecticides are effective for controlling Lutzomyia and Phlebotomus sand fly (Diptera: Psychodidae) vectors of Leishmania parasites. However,…”
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Comparison of In Vivo and In Vitro Methods for Blood Feeding of Phlebotomus papatasi (Diptera: Psychodidae) in the Laboratory by Denlinger, David S., Li, Andrew Y., Durham, Susan L., Lawyer, Phillip G., Anderson, Joseph L., Bernhardt, Scott A.

“…Phlebotomus papatasi Scopoli is a medically important insect that has been successfully colonized in the laboratory, and blood feeding is critical for colony…”
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Species diversity and relative abundance of phlebotomine sand flies (Diptera: Psychodidae) on three Army installations in the southern United States and susceptibility of a domestic sand fly to infection with Old World Leishmania major by Claborn, David M, Rowton, Edgar D, Lawyer, Phillip G, Brown, Grayson C, Keep, Lisa W

“…Leishmania infections in American veterans of Iraq and Afghanistan have raised concern that veterans could serve as reservoirs of Old World parasites for…”
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Stage-specific adhesion of Leishmania promastigotes to the sandfly midgut by Pimenta, P.F.P. (NIH, Bethesda, MD), Turco, S.J, McConville, M.J, Lawyer, P.G, Perkins, P.V, Sacks, D.L

“…Although leishmaniasis is transmitted to humans almost exclusively by the bite of infected phlebotomine sandflies, little is known about the molecules…”
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Lutzomyia longipalpis is a species complex: genetic divergence and interspecific hybrid sterility among three populations by Lanzaro, G C, Ostrovska, K, Herrero, M V, Lawyer, P G, Warburg, A

“…The sand fly Lutzomyia longipalpis is the vector of Leishmania donovani chagasi in Latin America. An analysis of genetic variability at 27 enzyme coding loci…”
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Plasmodium-infected Anopheles mosquitoes collected in Virginia and Maryland following local transmission of Plasmodium vivax malaria in Loudoun County, Virginia by Robert, Leon L, Santos-Ciminera, Patricia D, Andre, Richard G, Schultz, George W, Lawyer, Phillip G, Nigro, Joseph, Masuoka, Penny, Wirtz, Robert A, Neely, John, Gaines, David, Cannon, Charles E, Pettit, Denise, Garvey, Carol W, Goodfriend, David, Roberts, Donald R

“…Two recent outbreaks of locally acquired, mosquito-transmitted malaria in Virginia in 1998 and 2002 demonstrate the continued risk of endemic…”
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