Search Results - "Lawton, Philippe"
-
1
Fatty Acid Composition and Metabolism in Leishmania Parasite Species: Potential Biomarkers or Drug Targets for Leishmaniasis?
Published in International journal of molecular sciences (28-02-2023)“…Fatty acids have received growing interest in biology with the characterization of the enzymes allowing the complete fatty acid synthesis of this…”
Get full text
Journal Article -
2
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17
Published in Journal of biological engineering (24-04-2023)“…To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow well on mammalian…”
Get full text
Journal Article -
3
Ciprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondii
Published in PloS one (07-05-2015)“…Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital…”
Get full text
Journal Article -
4
In vitro effects of purine and pyrimidine analogues on Leishmania donovani and Leishmania infantum promastigotes and intracellular amastigotes
Published in Acta parasitologica (26-09-2017)“…Inhibition of parasite metabolic pathways is a rationale for new chemotherapeutic strategies. The pyrimidine and purine salvage pathways are thus targets…”
Get full text
Journal Article -
5
Echinococcus multilocularis Alkaline Phosphatase as a Marker for Metacestode Damage Induced by In Vitro Drug Treatment with Albendazole Sulfoxide and Albendazole Sulfone
Published in Antimicrobial Agents and Chemotherapy (01-08-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
6
Fatty Acid Composition and Metabolism in ILeishmania/I Parasite Species: Potential Biomarkers or Drug Targets for Leishmaniasis?
Published in International journal of molecular sciences (01-02-2023)“…Fatty acids have received growing interest in Leishmania biology with the characterization of the enzymes allowing the complete fatty acid synthesis of this…”
Get full text
Journal Article -
7
Oxygen uptake rate analysis to evaluate the impact of hydrodynamic stress on the growth of the avian cell line DuckCelt®-T17
Published in Biochemical engineering journal (01-12-2024)“…Scale-up of bioprocesses involving animal cell culture is hampered by the sensitivity of the cells to hydrodynamic stress, either from agitation or bubble…”
Get full text
Journal Article -
8
Changes in Lipid and Fatty Acid Composition During Intramacrophagic Transformation of Leishmania donovani Complex Promastigotes into Amastigotes
Published in Lipids (01-05-2017)“…Leishmania sp., are trypanosomatid parasites that are phagocytized by human and animal macrophages. Transformation from the vector promastigote stage to the…”
Get full text
Journal Article -
9
Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine macrophages
Published in Lipids (21-12-2022)“…Abstract Leishmania parasites are the causative agents of visceral or cutaneous leishmaniasis in humans and of canine leishmaniosis. The macrophage is the…”
Get full text
Journal Article -
10
Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17
Published in Journal of biological engineering (24-04-2023)“…Abstract Background To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow…”
Get full text
Journal Article -
11
Development of an oral nanovaccine for dogs against Echinococcus granulosus
Published in European journal of pharmaceutics and biopharmaceutics (01-11-2023)“…[Display omitted] Dogs are the main source of animal and human cystic echinococcosis caused by the Cestode parasite Echinococcus granulosus. Dog vaccination…”
Get full text
Journal Article -
12
Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine macrophages
Published in Lipids (01-03-2023)“…Leishmania parasites are the causative agents of visceral or cutaneous leishmaniasis in humans and of canine leishmaniosis. The macrophage is the predilected…”
Get full text
Journal Article -
13
Changes in Lipid and Fatty Acid Composition During Intramacrophagic Transformation of Leishmania donovani Complex Promastigotes into Amastigotes
Published in Lipids (04-02-2017)“…Abstract Leishmania sp., are trypanosomatid parasites that are phagocytized by human and animal macrophages. Transformation from the vector promastigote stage…”
Get full text
Journal Article -
14
Toxoplasma gondii: Identification and immune response against a group of proteins involved in cellular invasion
Published in Experimental parasitology (01-01-2012)“…[Display omitted] ► Toxoplasma gondii tachyzoites secreted a group of proteins into the medium. ► These proteins caused cell permeability and facilitated the…”
Get full text
Journal Article -
15
Synthesis and modulation properties of imidazo[4,5- b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter
Published in European journal of medicinal chemistry (01-06-2010)“…The syntheses of new N-polysubstituted imidazo[4,5- b]pyridine-7-one (IP, 5 and 8a–8f) and indazole-4,7-dione (ID, 9 and 10) derivatives are described. The…”
Get full text
Journal Article -
16
-
17
Sesquiterpenes from aerial parts of Ferula vesceritensis
Published in Phytochemistry (Oxford) (01-06-2008)“…Five daucane derivatives have been isolated from the aerial parts of Ferula vesceritensis (Apiaceae). From the dichloromethane extract of aerial parts of…”
Get full text
Journal Article -
18
Ciprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondii: e0125705
Published in PloS one (01-05-2015)“…Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital…”
Get full text
Journal Article -
19
Overexpression, purification and characterization of a hexahistidine-tagged recombinant extended nucleotide-binding domain 1 (NBD1) of the Cryptosporidium parvum CpABC3 for rational drug design
Published in Molecular and biochemical parasitology (01-03-2007)“…Its natural resistance to antiprotozoal chemotherapy characterizes the intestinal protozoan parasite Cryptosporidium parvum and the P-glycoprotein-related…”
Get full text
Journal Article -
20
Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum
Published in FEMS microbiology letters (12-09-2003)“…The effect of purine nucleosides on the in vitro growth of Cryptosporidium parvum was studied. Culturing the parasite in THP-1 cells for 72 h in growth medium…”
Get full text
Journal Article