Search Results - "Lawton, Philippe"

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  1. 1

    Fatty Acid Composition and Metabolism in Leishmania Parasite Species: Potential Biomarkers or Drug Targets for Leishmaniasis? by Leroux, Marine, Luquain-Costaz, Céline, Lawton, Philippe, Azzouz-Maache, Samira, Delton, Isabelle

    “…Fatty acids have received growing interest in biology with the characterization of the enzymes allowing the complete fatty acid synthesis of this…”
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    Journal Article
  2. 2

    Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17 by Tingaud, Valentine, Bordes, Claire, Al Mouazen, Eyad, Cogné, Claudia, Bolzinger, Marie-Alexandrine, Lawton, Philippe

    Published in Journal of biological engineering (24-04-2023)
    “…To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow well on mammalian…”
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    Journal Article
  3. 3

    Ciprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondii by Martins-Duarte, Erica S, Dubar, Faustine, Lawton, Philippe, da Silva, Cristiane França, Soeiro, Maria de Nazaré C, de Souza, Wanderley, Biot, Christophe, Vommaro, Rossiane C

    Published in PloS one (07-05-2015)
    “…Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital…”
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    Journal Article
  4. 4

    In vitro effects of purine and pyrimidine analogues on Leishmania donovani and Leishmania infantum promastigotes and intracellular amastigotes by Azzouz, Samira, Lawton, Philippe

    Published in Acta parasitologica (26-09-2017)
    “…Inhibition of parasite metabolic pathways is a rationale for new chemotherapeutic strategies. The pyrimidine and purine salvage pathways are thus targets…”
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    Journal Article
  5. 5

    Echinococcus multilocularis Alkaline Phosphatase as a Marker for Metacestode Damage Induced by In Vitro Drug Treatment with Albendazole Sulfoxide and Albendazole Sulfone by STETTLER, Marianne, SILES-LUCAS, Mar, SARCIRON, Elisabeth, LAWTON, Philippe, GOTTSTEIN, Bruno, HEMPHILL, Andrew

    Published in Antimicrobial Agents and Chemotherapy (01-08-2001)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  6. 6

    Fatty Acid Composition and Metabolism in ILeishmania/I Parasite Species: Potential Biomarkers or Drug Targets for Leishmaniasis? by Leroux, Marine, Luquain-Costaz, Céline, Lawton, Philippe, Azzouz-Maache, Samira, Delton, Isabelle

    “…Fatty acids have received growing interest in Leishmania biology with the characterization of the enzymes allowing the complete fatty acid synthesis of this…”
    Get full text
    Journal Article
  7. 7

    Oxygen uptake rate analysis to evaluate the impact of hydrodynamic stress on the growth of the avian cell line DuckCelt®-T17 by Tingaud, Valentine, Lawton, Philippe, Peralez, Johan, Nadri-Wolf, Madiha, Pitault, Isabelle, Cogné, Claudia, Errazuriz, Elisabeth, Al Mouazen, Eyad, Bordes, Claire

    Published in Biochemical engineering journal (01-12-2024)
    “…Scale-up of bioprocesses involving animal cell culture is hampered by the sensitivity of the cells to hydrodynamic stress, either from agitation or bubble…”
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    Journal Article
  8. 8

    Changes in Lipid and Fatty Acid Composition During Intramacrophagic Transformation of Leishmania donovani Complex Promastigotes into Amastigotes by Bouazizi-Ben Messaoud, Hana, Guichard, Marion, Lawton, Philippe, Delton, Isabelle, Azzouz-Maache, Samira

    Published in Lipids (01-05-2017)
    “…Leishmania sp., are trypanosomatid parasites that are phagocytized by human and animal macrophages. Transformation from the vector promastigote stage to the…”
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    Journal Article
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    Experimental studies from shake flasks to 3 L stirred tank bioreactor of nutrients and oxygen supply conditions to improve the growth of the avian cell line DuckCelt®-T17 by Tingaud, Valentine, Bordes, Claire, Al Mouazen, Eyad, Cogné, Claudia, Bolzinger, Marie-Alexandrine, Lawton, Philippe

    Published in Journal of biological engineering (24-04-2023)
    “…Abstract Background To produce viral vaccines, avian cell lines are interesting alternatives to replace the egg-derived processes for viruses that do not grow…”
    Get full text
    Journal Article
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  13. 13

    Changes in Lipid and Fatty Acid Composition During Intramacrophagic Transformation of Leishmania donovani Complex Promastigotes into Amastigotes by Bouazizi-Ben Messaoud, Hana, Guichard, Marion, Lawton, Philippe, Delton, Isabelle, Azzouz-Maache, Samira

    Published in Lipids (04-02-2017)
    “…Abstract Leishmania sp., are trypanosomatid parasites that are phagocytized by human and animal macrophages. Transformation from the vector promastigote stage…”
    Get full text
    Journal Article
  14. 14

    Toxoplasma gondii: Identification and immune response against a group of proteins involved in cellular invasion by Azzouz, Samira, Maache, Mimoun, Osuna, Antonio, Lawton, Philippe, Pétavy, Anne Françoise

    Published in Experimental parasitology (01-01-2012)
    “…[Display omitted] ► Toxoplasma gondii tachyzoites secreted a group of proteins into the medium. ► These proteins caused cell permeability and facilitated the…”
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    Journal Article
  15. 15

    Synthesis and modulation properties of imidazo[4,5- b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter by Zeinyeh, Waël, Xia, Hexue, Lawton, Philippe, Radix, Sylvie, Marminon, Christelle, Nebois, Pascal, Walchshofer, Nadia

    Published in European journal of medicinal chemistry (01-06-2010)
    “…The syntheses of new N-polysubstituted imidazo[4,5- b]pyridine-7-one (IP, 5 and 8a–8f) and indazole-4,7-dione (ID, 9 and 10) derivatives are described. The…”
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    Sesquiterpenes from aerial parts of Ferula vesceritensis by Oughlissi-Dehak, Karima, Lawton, Philippe, Michalet, Serge, Bayet, Christine, Darbour, Nicole, Hadj-Mahammed, Mahfoud, Badjah-Hadj-Ahmed, Yacine A., Dijoux-Franca, Marie-Geneviève, Guilet, David

    Published in Phytochemistry (Oxford) (01-06-2008)
    “…Five daucane derivatives have been isolated from the aerial parts of Ferula vesceritensis (Apiaceae). From the dichloromethane extract of aerial parts of…”
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    Journal Article
  18. 18

    Ciprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondii: e0125705 by Martins-Duarte, Erica S, Dubar, Faustine, Lawton, Philippe, Silva, Cristiane Francada, Soeiro, de NazareC, Souza, Wanderley de, Biot, Christophe, Vommaro, Rossiane C

    Published in PloS one (01-05-2015)
    “…Toxoplasmosis, caused by the protozoan Toxoplasma gondii, is a worldwide disease whose clinical manifestations include encephalitis and congenital…”
    Get full text
    Journal Article
  19. 19

    Overexpression, purification and characterization of a hexahistidine-tagged recombinant extended nucleotide-binding domain 1 (NBD1) of the Cryptosporidium parvum CpABC3 for rational drug design by Lawton, Philippe, Pélandakis, Michel, Pétavy, Anne-Françoise, Walchshofer, Nadia

    Published in Molecular and biochemical parasitology (01-03-2007)
    “…Its natural resistance to antiprotozoal chemotherapy characterizes the intestinal protozoan parasite Cryptosporidium parvum and the P-glycoprotein-related…”
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    Journal Article
  20. 20

    Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum by Lawton, Philippe, Hejl, Carine, Mancassola, Roselyne, Naciri, Muriel, Petavy, Anne-Françoise

    Published in FEMS microbiology letters (12-09-2003)
    “…The effect of purine nucleosides on the in vitro growth of Cryptosporidium parvum was studied. Culturing the parasite in THP-1 cells for 72 h in growth medium…”
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    Journal Article