Search Results - "Lawton, Geoffrey"

Potent selective inhibitors of protein kinase C by Davis, Peter D., Hill, Christopher H., Keech, Elizabeth, Lawton, Geoffrey, Nixon, John S., Sedgwick, Anthony D., Wadsworth, Julie, Westmacott, Donald, Wilkinson, Sandra E.

“…A series of potent, selective inhibitors of protein kinase C has been derived from the structural lead provided by the microbial broth products, staurosporine…”
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Initiative for improving pharmacist satisfaction with work schedules by REUPPEL, Randy, SCHEIDER, Diane, LAWTON, Geoffrey C

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Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides by Davis, Peter D, Hill, Christopher H, Lawton, Geoffrey, Nixon, John S, Wilkinson, Sandra E, Hurst, Steven A, Keech, Elizabeth, Turner, Susan E

“…The design and synthesis of a series of novel inhibitors of protein kinase C (PKC) is described. These 2,3-bisarylmaleimides were derived from the structural…”
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Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors by Bottomley, K M, Borkakoti, N, Bradshaw, D, Brown, P A, Broadhurst, M J, Budd, J M, Elliott, L, Eyers, P, Hallam, T J, Handa, B K, Hill, C H, James, M, Lahm, H W, Lawton, G, Merritt, J E, Nixon, J S, Röthlisberger, U, Whittle, A, Johnson, W H

“…N-terminal analysis of aggrecan fragments lost from bovine nasal cartilage cultured in the presence of recombinant human interleukin 1alpha revealed a…”
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Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity by Davis, Peter D, Elliott, Lucy H, Harris, William, Hill, Christopher H, Hurst, Steven A, Keech, Elizabeth, Kumar, M. K. Hari, Lawton, Geoffrey, Nixon, John S, Wilkinson, Sandra E

“…A hypothetical mode of inhibition of protein kinase C (PKC) by the natural product staurosporine has been used as a basis for the design of substituted…”
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Initiative for improving pharmacist satisfaction with work schedules by Reuppel, Randy, Scheider, Diane, Lawton, Geoffrey C

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Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction by Bit, Rino A., Davis, Peter D., Elliott, Lucy H., Harris, William, Hill, Christopher H., Keech, Elizabeth, Kumar, Hari, Lawton, Geoffrey, Maw, Anna, Nixon, John S., Vesey, David R., Wadsworth, Julie, Wilkinson, Sandra E.

“…The protein kinase inhibitor staurosporine has been used to design a series of selective bisindolylmaleimide inhibitors of protein kinase C (PKC). Guided by…”
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K252a is a potent and selective inhibitor of phosphorylase kinase by Elliott, L H, Wilkinson, S E, Sedgwick, A D, Hill, C H, Lawton, G, Davis, P D, Nixon, J S

“…The inhibition of phosphorylase kinase by a number of protein kinase inhibitors was examined. Both K252a and staurosporine are potent inhibitors of…”
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A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli by Muid, Robert E., Dale, M.Maureen, Davis, Peter D., Elliott, Lucy H., Hill, Christopher H., Kumar, Hari, Lawton, Geoffrey, Twomey, Breda M., Wadsworth, Julie, Wilkinson, Sandra E., Nixon, John S.

“…A novel, bis-indolylmaleimide, Ro 31-8425, bearing a conformationally restricted side chain, inhibits protein kinase C isolated from rat brain and human…”
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Coordinated Diagnostic Imaging by Lawton, Geoffrey

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New potent inhibitors of angiotensin converting enzyme by Attwood, Michael R., Francis, R.John, Hassall, Cedric H., Kröhn, Antonin, Lawton, Geoffrey, Natoff, Ian L., Nixon, John S., Redshaw, Sally, Thomas, W.Anthony

“…Using an earlier model of the favoured orientation of binding functions of angiotensin converting enzyme (ACE) inhibitors, it has been possible to postulate a…”
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Coeliac stenosis or occlusion with aneurysm of the collateral supply by Sutton, D, Lawton, G

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Angiographic diagnosis of aneurysms involving the hepatic artery by Sutton, D, Lawton, G

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