Search Results - "Lawson, Gregory"
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Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection
Published in Cell host & microbe (18-10-2012)“…Commensal bacteria impact host health and immunity through various mechanisms, including the production of immunomodulatory molecules. Bacteroides fragilis…”
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Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy
Published in Journal of the American Society of Nephrology (01-03-2012)“…TGF-β1 upregulates microRNA-192 (miR-192) in cultured glomerular mesangial cells and in glomeruli from diabetic mice. miR-192 not only increases collagen…”
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Charged-Iron-Particles Found in Galactic Cosmic Rays are Potent Inducers of Epithelial Ovarian Tumors
Published in Radiation research (01-08-2018)“…Astronauts traveling in deep space are exposed to high-charge and energy (HZE) particles from galactic cosmic rays. We have previously determined that…”
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Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros
Published in Nature immunology (01-10-2013)“…The transcription factor Ikaros, which is essential for lymphocyte development, contains multiple zinc fingers. Smale and colleagues show that mice lacking…”
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In Utero Exposure to Benzo[a]pyrene Induces Ovarian Mutations at Doses That Deplete Ovarian Follicles in Mice
Published in Environmental and molecular mutagenesis (01-06-2019)“…Polycyclic aromatic hydrocarbons like benzo[a]pyrene (BaP) are ubiquitous environmental contaminants formed during incomplete combustion of organic materials…”
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Knockout of the transcription factor NRF2 disrupts spermatogenesis in an age-dependent manner
Published in Free radical biology & medicine (15-11-2010)“…Oxidative stress occurs when generation of reactive oxygen species (ROS) overwhelms antioxidant defenses. Oxidative stress has been associated with male…”
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Transgrade Dorsal Root Ganglion Stimulation as a Salvage Technique for Three Different Anatomical Barriers: A Case Series
Published in Neuromodulation (Malden, Mass.) (01-06-2021)“…Dorsal root ganglion stimulation (DRGS) is an effective treatment for complex regional pain syndrome (CRPS) and post-surgical neuropathic pain. However, some…”
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Ability of mini-implant–facilitated micro-osteoperforations to accelerate tooth movement in rats
Published in American journal of orthodontics and dentofacial orthopedics (01-12-2016)“…Introduction Although current techniques for accelerated tooth movement often involve invasive surgical procedures, micro-osteoperforations (MOPs) using…”
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Glutathione-Deficient Mice have Increased Sensitivity to Transplacental Benzo[a]pyrene-Induced Premature Ovarian Failure and Ovarian Tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-01-2013)“…Polycyclic aromatic hydrocarbons (PAH) such as benzo[a]pyrene (BaP) are ubiquitous environmental pollutants found in tobacco smoke, air pollution, and grilled…”
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The XX sex chromosome complement in mice is associated with increased spontaneous lupus compared with XY
Published in Annals of the rheumatic diseases (01-08-2012)“…Many autoimmune diseases are characterised by a female predominance. This may be caused by sex hormones, sex chromosomes or both. This report uses a transgenic…”
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ORAI1 deficiency impairs activated T cell death and enhances T cell survival
Published in The Journal of immunology (1950) (01-10-2011)“…ORAI1 is a pore subunit of Ca(2+) release-activated Ca(2+) channels that mediate TCR stimulation-induced Ca(2+) entry. A point mutation in ORAI1 (ORAI1(R91W))…”
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Effect of Husbandry Practices on the Fecal Microbiota of C57BL/6J Breeding Colonies Housed in 2 Different Barrier Facilities in the Same Institution
Published in Journal of the American Association for Laboratory Animal Science (01-01-2023)“…Evidence showing a relationship between the mouse gut microbiome and properties such as phenotype and reaction to therapeutic agents and other treatments has…”
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IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer
Published in Cancer research (Chicago, Ill.) (01-08-2011)“…The insulin-like growth factor binding protein IGFBP-3 is a proapoptotic and antiangiogenic protein in prostate cancer (CaP). Epidemiologic studies suggest…”
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Response to Protocol Review Scenario: PAM specialist: report without fear
Published in Lab animal (01-07-2017)Get full text
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PTEN dosage is essential for neurofibroma development and malignant transformation
Published in Proceedings of the National Academy of Sciences - PNAS (17-11-2009)“…Patients with neurofibromatosis type 1 (NF1) carry approximately a 10% lifetime risk of developing a malignant peripheral nerve sheath tumor (MPNST). Although…”
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Etiopathogenesis of Mandibulofacial and Maxillofacial Abscesses in Mice
Published in Comparative medicine (01-06-2010)“…The etiologic agent of mandibulofacial and maxillofacial abscesses in mice is reportedly coagulase-positive Staphylococcus aureus. Although suggested to be…”
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Factors in the Selection of Surface Disinfectants for Use in a Laboratory Animal Setting
Published in Journal of the American Association for Laboratory Animal Science (01-03-2016)“…Because surface disinfectants are an important means of pathogen control within laboratory animal facilities, these products must have an appropriate spectrum…”
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Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected with Aspiculuris tetraptera
Published in Journal of the American Association for Laboratory Animal Science (01-05-2017)“…The entry of infectious agents in rodent colonies occurs despite robust sentinel monitoring programs, strict quarantine measures, and stringent biosecurity…”
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Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model
Published in Cancer research (Chicago, Ill.) (01-06-2007)“…Replication-competent retrovirus (RCR) vectors are intrinsically incapable of infecting quiescent cells and have been shown to achieve highly efficient and…”
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Mars Climate Sounder limb profile retrieval of atmospheric temperature, pressure, and dust and water ice opacity
Published in Journal of Geophysical Research - Planets (01-10-2009)“…The Mars Climate Sounder (MCS) onboard the Mars Reconnaissance Orbiter is the latest of a series of investigations devoted to improving the understanding of…”
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