Search Results - "Lawrenson, K."

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    COVID-19 testing in outbreak-free care homes: what are the public health benefits? by Green, R., Tulloch, J.S.P., Tunnah, C., Coffey, E., Lawrenson, K., Fox, A., Mason, J., Barnett, R., Constantine, A., Shepherd, W., Ashton, M., Beadsworth, M.B.J., Vivancos, R., Hall, I., Walker, N., Ghebrehewet, S.

    Published in The Journal of hospital infection (01-05-2021)
    “…COVID-19 care home outbreaks represent a significant proportion of COVID-19 morbidity and mortality in the UK. National testing initially focused on…”
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    Journal Article
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    Targeting Src in endometriosis-associated ovarian cancer by Manek, R, Pakzamir, E, Mhawech-Fauceglia, P, Pejovic, T, Sowter, H, Gayther, S A, Lawrenson, K

    Published in Oncogenesis (New York, NY) (15-08-2016)
    “…The SRC proto-oncogene is commonly overexpressed or activated during cancer development. Src family kinase inhibitors are approved for the treatment of certain…”
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    Journal Article
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    In vitro three-dimensional modelling of human ovarian surface epithelial cells by Lawrenson, K., Benjamin, E., Turmaine, M., Jacobs, I., Gayther, S., Dafou, D.

    Published in Cell proliferation (01-06-2009)
    “…Objectives:  Ninety percent of malignant ovarian cancers are epithelial and thought to arise from the ovarian surface epithelium (OSE). We hypothesized that…”
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    Journal Article
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    Characteristics of Suspected Endometriosis without Histologic Confirmation by Krajisnik, A., Medeiros, F., Lawrenson, K., Siedhoff, M.T., Truong, M.D., Wright, K.N.

    Published in Journal of minimally invasive gynecology (01-11-2020)
    “…We aim to describe the clinical and laparoscopic features of suspected endometriosis lacking histologic confirmation. Retrospective cohort study. Quaternary…”
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    Journal Article
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    Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells by Lakshminarasimhan, Ranjani, Andreu-Vieyra, Claudia, Lawrenson, Kate, Duymich, Christopher E, Gayther, Simon A, Liang, Gangning, Jones, Peter A

    Published in Cancer letters (10-08-2017)
    “…Abstract The chromatin remodeler AT-Rich Interactive Domain 1A (ARID1A) is frequently mutated in ovarian clear cell carcinoma (OCCC) and endometriosis…”
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    Journal Article
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    Modelling neoplastic progression in epithelial ovarian cancer by Lawrenson, K

    Published 01-01-2010
    “…A national screening programme could significantly reduce mortality from epithelial ovarian cancer (EOC). The biological events that occur in the early stages…”
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    Dissertation
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