Search Results - "Lawrence K. Silbart"

Mycoplasma gallisepticum lipid associated membrane proteins up-regulate inflammatory genes in chicken tracheal epithelial cells via TLR-2 ligation through an NF-κB dependent pathway by Majumder, Sanjukta, Zappulla, Frank, Silbart, Lawrence K

“…Mycoplasma gallisepticum-mediated respiratory inflammation in chickens is associated with accumulation of leukocytes in the tracheal submucosa. However the…”
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Identification of TAPBPL as a novel negative regulator of T‐cell function by Lin, Yujun, Cui, Cheng, Su, Min, Silbart, Lawrence K, Liu, Haiyan, Zhao, Jin, He, Lang, Huang, Yuanmao, Xu, Dexin, Wei, Xiaodan, Du, Qian, Lai, Laijun

“…T cell stimulatory and inhibitory molecules are critical for the regulation of immune responses. In this study, we identify a novel T cell co‐inhibitory…”
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Strains of Faecalibacterium prausnitzii and its extracts reduce blood glucose levels, percent HbA1c, and improve glucose tolerance without causing hypoglycemic side effects in diabetic and prediabetic mice by Kallassy, John, Gagnon, Emily, Rosenberg, Dawn, Silbart, Lawrence K, McManus, Simon A

“…IntroductionThe commensal bacterium Faecalibacterium prausnitzii is a prominent member of the microbiome of animals and humans, and it plays an important role…”
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Enhanced phosphorus nutrition in monocots and dicots over-expressing a phosphorus-responsive type I H+-pyrophosphatase by Yang, Haibing, Knapp, Jane, Koirala, Pratistha, Rajagopal, Divya, Peer, Wendy Ann, Silbart, Lawrence K, Murphy, Angus, Gaxiola, Roberto A

“…Plants challenged by limited phosphorus undergo dramatic morphological and architectural changes in their root systems in order to increase their absorptive…”
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A Microarray Biosensor for Multiplexed Detection of Microbes Using Grating-Coupled Surface Plasmon Resonance Imaging by Marusov, Gregory, Sweatt, Andrew, Pietrosimone, Kathryn, Benson, David, Geary, Steven J, Silbart, Lawrence K, Challa, Sreerupa, Lagoy, Jacqueline, Lawrence, David A, Lynes, Michael A

“…Grating-coupled surface plasmon resonance imaging (GCSPRI) utilizes an optical diffraction grating embossed on a gold-coated sensor chip to couple collimated…”
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Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease by Mara, Arlind B., Gavitt, Tyler D., Tulman, Edan R., Miller, Jeremy M., He, Wu, Reinhardt, Emily M., Ozyck, R. Grace, Goodridge, Meagan L., Silbart, Lawrence K., Szczepanek, Steven M., Geary, Steven J.

“…Bacterial lipoproteins are an often-underappreciated class of microbe-associated molecular patterns with potent immunomodulatory activity. We previously…”
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Interaction of Mycoplasma gallisepticum with Chicken Tracheal Epithelial Cells Contributes to Macrophage Chemotaxis and Activation by Majumder, Sanjukta, Silbart, Lawrence K

“…Mycoplasma gallisepticum colonizes the chicken respiratory mucosa and mediates a severe inflammatory response hallmarked by subepithelial leukocyte…”
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Xenoepitope Substitution Avoids Deceptive Imprinting and Broadens the Immune Response to Foot-and-Mouth Disease Virus by Szczepanek, Steven M, Barrette, Roger W, Rood, Debra, Alejo, Diana, Silbart, Lawrence K

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Use of Inactivated Escherichia coli Enterotoxins To Enhance Respiratory Mucosal Adjuvanticity during Vaccination in Swine by Barrette, Roger W, Szczepanek, Steven M, Rood, Debra, Challa, Sreerupa, Avery, Naomi, Vajdy, Michael, Kramer, Ed, Rodriguez, Luis, Silbart, Lawrence K

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Correlates of Immune Protection in Chickens Vaccinated with Mycoplasma gallisepticum Strain GT5 following Challenge with Pathogenic M. gallisepticum Strain Rlow by JAVED, Mohammed A, FRASCA, Salvatore JR, ROOD, Debra, CECCHINI, Katharine, GLADD, Martha, GEARY, Steven J, SILBART, Lawrence K

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Immunologic Pathways in Protective versus Maladaptive Host Responses to Attenuated and Pathogenic Strains of Mycoplasma gallisepticum by Beaudet, Jessica, Tulman, Edan R, Pflaum, Katherine, Canter, Jessica A, Silbart, Lawrence K, Geary, Steven J

“…Mycoplasmas are small bacterial commensals or pathogens that commonly colonize host mucosal tissues and avoid rapid clearance, in part by stimulating…”
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The VP1 G-H loop hypervariable epitope contributes to protective immunity against Foot and Mouth Disease Virus in swine by Fernandez-Sainz, Ignacio, Gavitt, Tyler D., Koster, Marla, Ramirez-Medina, Elizabeth, Rodriguez, Yelitza Y., Wu, Ping, Silbart, Lawrence K., de Los Santos, Teresa, Szczepanek, Steven M.

“…Foot and Mouth Disease is a highly contagious and economically important disease of livestock. While vaccination is often effective at controlling viral…”
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Quantifying Specific Antibody Concentrations by Enzyme-Linked Immunosorbent Assay Using Slope Correction by Barrette, Roger W, Urbonas, Jessica, Silbart, Lawrence K

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Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab) by Wanczyk, Heather, Barker, Tolga, Rood, Debra, Zapata, Daniel I, Howell, Amy R, Richardson, Stewart K, Zinckgraf, John, Marusov, Gregory P, Lynes, Michael A, Silbart, Lawrence K

“…Smokeless tobacco products have been associated with increased risks of oro-pharyngeal cancers, due in part to the presence of tobacco-specific nitrosamines…”
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Labeling and Intracellular Tracking of Functionally Active Plasmid DNA with Semiconductor Quantum Dots by Srinivasan, Charudharshini, Lee, Jeunghoon, Papadimitrakopoulos, Fotios, Silbart, Lawrence K, Zhao, Minhua, Burgess, Diane J

“…Semiconductor nanocrystal quantum dots (QDs) allow long-term imaging in the cellular environment with high photostability. QD biolabeling techniques have…”
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Safety Evaluation of Autologous Tissue Vaccine Cancer Immunotherapy in a Canine Model by Crossley, Rachel A, Matz, Alyssa, Dew, Terry, Kalinauskas, Ashley, Faucette, Nicole, Poff, Brad, Silbart, Lawrence K, Suckow, Mark A

“…Previous work in rodent models showed that an autologous tissue vaccine is both a safe and effective approach for treating cancer; however, as a translational…”
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Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs by Challa, Sreerupa, Szczepanek, Steven M., Rood, Debra, Barrette, Roger W., Silbart, Lawrence K.

“…Peptides corresponding to the foot-and-mouth disease virus VP1 G-H loop are capable of inducing neutralizing antibodies in some species but are considered…”
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Outer membrane protein A (OmpA) of Cronobacter sakazakii binds fibronectin and contributes to invasion of human brain microvascular endothelial cells by Nair, Manoj Kumar Mohan, Venkitanarayanan, Kumar, Silbart, Lawrence K, Kim, Kwang Sik

“…Cronobacter sakazakii is an emerging foodborne pathogen that causes severe meningitis and meningoencephalitis in neonates. Currently there is a dearth of…”
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Broncho-alveolar macrophages express chemokines associated with leukocyte migration in a mouse model of asthma by surnameSiddiqui, givennameShafiuddin, surnameSecor, givennameEric R., surnameSilbart, givennameLawrence K.

“…•Mice with OVA-induced asthma had large numbers of M2 macrophages in the airway lumen.•These M2 macrophages expressed many M2 genes including arginase 1, YM-1…”
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B cells oppose Mycoplasmapneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs by Gavitt, Tyler D., Mara, Arlind B., Goodridge, Meagan L., Ozyck, Rosemary Grace, Reinhardt, Emily, Miller, Jeremy M., Hunte, Morgan, Tulman, Edan R., Frasca Jr, Salvatore, Silbart, Lawrence K., Geary, Steven J., Szczepanek, Steven M.

“…Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and…”
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