Search Results - "Lawrence , Chad"
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Radical Compatibility with Nonaqueous Electrolytes and Its Impact on an All-Organic Redox Flow Battery
Published in Angewandte Chemie (International ed.) (20-07-2015)“…Nonaqueous redox flow batteries hold the promise of achieving higher energy density because of the broader voltage window than aqueous systems, but their…”
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Journal Article -
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Carbon-Detected 15N NMR Spin Relaxation of an Intrinsically Disordered Protein: FCP1 Dynamics Unbound and in Complex with RAP74
Published in The journal of physical chemistry letters (17-05-2012)“…Intrinsically disordered proteins (IDPs) lack unique 3D structures under native conditions and as such exist as highly dynamic ensembles in solution. We…”
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Carbohydrates protect protein against abiotic fragmentation by soil minerals
Published in Scientific reports (16-01-2018)“…The degradation and turnover of soil organic matter is an important part of global carbon cycling and of particular importance with respect to attempts to…”
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Journal Article -
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Assessing Coupled Protein Folding and Binding Through Temperature-Dependent Isothermal Titration Calorimetry
Published in Methods in enzymology (01-01-2016)“…Broad interest in the thermodynamic driving forces of coupled macromolecular folding and binding is motivated by the prevalence of disorder-to-order…”
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Journal Article -
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Role of Ordered Proteins in the Folding-Upon-Binding of Intrinsically Disordered Proteins
Published in The journal of physical chemistry letters (06-03-2014)“…In this work, we quantitatively investigate the thermodynamic analogy between the folding of monomeric proteins and the interactions of intrinsically…”
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Journal Article -
6
Carbon-Detected (15)N NMR Spin Relaxation of an Intrinsically Disordered Protein: FCP1 Dynamics Unbound and in Complex with RAP74
Published in The journal of physical chemistry letters (17-05-2012)“…Intrinsically disordered proteins (IDPs) lack unique 3D structures under native conditions and as such exist as highly dynamic ensembles in solution. We…”
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Journal Article -
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The disordered C-terminus of the RNA Polymerase II phosphatase FCP1 is partially helical in the unbound state
Published in Biochemical and biophysical research communications (08-07-2011)“…► Carbon-detected NMR reveals new details of FCP1 interactions with RAP74. ► Titrations with TFE and urea reveal partial helix formation in unbound FCP1. ► NMR…”
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Journal Article -
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Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
Published in mAbs (02-01-2019)“…The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can…”
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Journal Article -
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Chemical shifts-based similarity restraints improve accuracy of RNA structures determined via NMR
Published in RNA (Cambridge) (01-12-2020)“…Determination of structure of RNA via NMR is complicated in large part by the lack of a precise parameterization linking the observed chemical shifts to the…”
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Journal Article -
10
Radical Compatibility with Nonaqueous Electrolytes and Its Impact on an All-Organic Redox Flow Battery
Published in Angewandte Chemie (20-07-2015)“…Nonaqueous redox flow batteries hold the promise of achieving higher energy density because of the broader voltage window than aqueous systems, but their…”
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Journal Article -
11
An Isolable Azide Adduct of Titanium(II) Follows Bifurcated Deazotation Pathways to an Imide
Published in Journal of the American Chemical Society (12-01-2022)“…AdN3 (Ad = 1-adamantyl) reacts with the tetrahedral TiII complex [(Tp tBu,Me)TiCl] (Tp tBu,Me = hydrotris(3-tert-butyl-5-methylpyrazol-1-yl)borate) to…”
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Journal Article -
12
An Instrumental Case Study of Confirmative Evaluation in the Continuous Improvement of Online Remote Leaders’ Work
Published 01-01-2022“…Confirmative evaluation is often noted as an important element of models of Human Performance Technology and Performance Improvement, but there exists…”
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Dissertation -
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Assessing Intrinsically Disordered Protein Structure and Function through Carbon Detected NMR
Published in The FASEB journal (01-04-2015)“…Abstract only Intrinsically Disordered Proteins (IDPs) partially or completely lack a co‐operatively folded structure under native conditions, preventing their…”
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14. A novel cytogenomic approach to diagnosis of plasma cell neoplasms
Published in Cancer genetics (01-10-2018)Get full text
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16
Presidential illness and disability: The health and performance of presidents from 1789-1901
Published 01-01-2013“…Presidential health and performance has been a subject of study by both political scientists and historians, many of whom have examined the health of our…”
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Dissertation -
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Development of novel methodology to determine the functional role of disorder in the FCP1/RAP74 binding interaction
Published 2013“…Modern structural biology currently holds the paradigm that structure determines function. Intrinsically disordered proteins are a unique class of proteins…”
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Dissertation -
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Acoustic Daylight: Passive acoustic imaging using ambient noise
Published 01-01-1997“…Active and passive sonar are the best methods of exploring the ocean over large distances since the ocean is rather transparent to sound. Ambient noise often…”
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Dissertation -
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Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
Published in mAbs (02-01-2019)“…The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can…”
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Voice and Obviation in Athabaskan and Other Languages
Published 01-01-1989“…Athabaskan languages express the promotion and demotion of nominal arguments by three different grammatical systems. The diachronically oldest is the misnamed…”
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Dissertation