Search Results - "Lawrence, Ross F."
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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
Published in Chemical research in toxicology (01-01-1992)“…Previous kinetic studies have identified a high-affinity (S)-warfarin 7-hydroxylase present in human liver microsomes which appears to be responsible for the…”
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Quantitation of zoledronic acid in murine bone by liquid chromatography coupled with tandem mass spectrometry
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-09-2013)“…•Report of a mass spectrometry method for the detection of zoledronic acid in bone.•This assay was applied to detect zoledronic acid in murine bone from…”
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Synthesis of (.+-.)-catharanthine, (+)-anhydrovinblastine, and (-)-anhydrovincovaline
Published in Journal of the American Chemical Society (01-01-1987)Get full text
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Indole alkaloid synthesis via Claisen rearrangement. Total synthesis of secodine
Published in Journal of the American Chemical Society (01-05-1981)Get full text
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Analysis of cyclophosphamide and five metabolites from human plasma using liquid chromatography–mass spectrometry and gas chromatography–nitrogen–phosphorus detection
Published in Journal of chromatography. B, Biomedical sciences and applications (24-09-1999)“…An assay method for the quantification of cyclophosphamide (CY) and five metabolites from human plasma is presented. The procedure is adapted to the chemical…”
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The insertion and extrusion of heterosulfur bridges. IX: Sulfur bridging in 2-phenylnaphthalene
Published in Journal of heterocyclic chemistry (01-08-1978)“…Sulfur bridging of 2‐phenylnaphlhalene (3) to form benzo[b ]naphtho[2,1‐d]thiophene (5) (main product) and the isomeric benzo[b]naphtho[2,3‐d]thiophene (4) is…”
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Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography–mass spectrometry
Published in Journal of chromatography. B, Biomedical sciences and applications (12-05-2000)“…This report describes an assay for the H 1-receptor antagonist, terfenadine, and its two primary metabolites, terfenadine alcohol (TOH) and azacyclonol (AZ),…”
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TOTAL WAR AND THE UNITED NATIONS
Published in Pakistan horizon (01-09-1964)Get full text
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Stability Enhancement for Peptide Analysis by Electrospray Using the Triple Quadrupole Mass Spectrometer
Published in Analytical biochemistry (01-08-1997)“…Electrospray ionization sources, used with triple quadrupole mass spectrometers from PE/Sciex (API III+), Micromass (Quattro II), and Finnigan (TSQ 7000), were…”
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The insertion and extrusion of heterosulfur bridges. X. Conversions in the triphenylene-triphenylo[4,5-bcd] thiophene system
Published in Journal of heterocyclic chemistry (01-04-1979)“…Sulfur bridging of triphenylene (3) to form triphenylo[4,5‐bcd]thiophene (4) is effected in 18% yield by means of hydrogen sulfide and a molybdena catalyst…”
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Chemical synthesis, absolute configuration, and stereochemistry of formation of 10-hydroxywarfarin: a major oxidative metabolite of (+)-(R)-warfarin from hepatic microsomal preparations
Published in Chirality (New York, N.Y.) (1990)“…The synthesis of a diastereomerically pure 10-hydroxywarfarin [4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-1 benzopyran-2-one] was accomplished in three…”
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The insertion and extrusion of heterosulfur bridges. VII. Desulfurization of phenanthro[4,5-bcd]thiophene by means of methanol and a molybdena catalyst
Published in Journal of heterocyclic chemistry (01-05-1978)“…Phenanthro[4,5‐bcd]thiophene (1) is converted into phenanthrene (2) (50%) and a mixture of methylphenanthrenes (3) (12%) by means of methanol and a sulfided…”
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The insertion and extrusion of heterosulfur bridges. XI. Desulfurizations of condensed thiophenes by means of methanol and a molybdena catalyst
Published in Journal of heterocyclic chemistry (01-06-1980)“…Desulfurizations of 2‐methyl‐ (1b), 4‐methyl‐ (1c), and 4,6‐dimethyldibenzothiophenes (1d), benzo[b]thiophene (2), and benzo[b]naphtho[2,1‐d]thiophene (5) were…”
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The insertion and extrusion of heterosulfur bridges. XII. Selectivity and side reactions in the bridging process
Published in Journal of heterocyclic chemistry (01-09-1984)“…1‐Phenylnaphthalene undergoes sulfur bridging at 500° in the presence of hydrogen sulfide and a heterogeneous catalyst to produce…”
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15
Comparative chromatographic adsorbabilities of some azines, thioles and thienopyridines, their heteroatom oxides and other derivatives on silica gel
Published in Journal of heterocyclic chemistry (01-01-1979)“…Thin layer chromatographic Rf data on silica gel are reported for 64 compounds containing either a thiole sulfur atom, one or more azine nitrogen atoms, or…”
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