Search Results - "Lawrence, Ross F"

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions by Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F

“…Previous kinetic studies have identified a high-affinity (S)-warfarin 7-hydroxylase present in human liver microsomes which appears to be responsible for the…”
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Quantitation of zoledronic acid in murine bone by liquid chromatography coupled with tandem mass spectrometry by Raccor, Brianne S., Sun, Jianxun, Lawrence, Ross F., Li, Lei, Zhang, Hai, Somerman, Martha J., Totah, Rheem A.

“…•Report of a mass spectrometry method for the detection of zoledronic acid in bone.•This assay was applied to detect zoledronic acid in murine bone from…”
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Synthesis of (.+-.)-catharanthine, (+)-anhydrovinblastine, and (-)-anhydrovincovaline by Raucher, Stanley, Bray, Brian L, Lawrence, Ross F

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Indole alkaloid synthesis via Claisen rearrangement. Total synthesis of secodine by Raucher, Stanley, Macdonald, James E, Lawrence, Ross F

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Analysis of cyclophosphamide and five metabolites from human plasma using liquid chromatography–mass spectrometry and gas chromatography–nitrogen–phosphorus detection by Kalhorn, Thomas F, Ren, Song, Howald, William N, Lawrence, Ross F, Slattery, John T

“…An assay method for the quantification of cyclophosphamide (CY) and five metabolites from human plasma is presented. The procedure is adapted to the chemical…”
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The insertion and extrusion of heterosulfur bridges. IX: Sulfur bridging in 2-phenylnaphthalene by Klemm, L. H., Karchesy, Joseph J., Lawrence, Ross F.

“…Sulfur bridging of 2‐phenylnaphlhalene (3) to form benzo[b ]naphtho[2,1‐d]thiophene (5) (main product) and the isomeric benzo[b]naphtho[2,3‐d]thiophene (4) is…”
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Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography–mass spectrometry by Madani, Soraya, Howald, William N, Lawrence, Ross F, Shen, Danny D

“…This report describes an assay for the H 1-receptor antagonist, terfenadine, and its two primary metabolites, terfenadine alcohol (TOH) and azacyclonol (AZ),…”
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TOTAL WAR AND THE UNITED NATIONS by Ross, Lawrence F. J.

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Stability Enhancement for Peptide Analysis by Electrospray Using the Triple Quadrupole Mass Spectrometer by Wang, Houle, Lim, Kheng B., Lawrence, Ross F., Howald, William N., Taylor, J.Alex, Ericsson, Lowell H., Walsh, Kenneth A., Hackett, Murray

“…Electrospray ionization sources, used with triple quadrupole mass spectrometers from PE/Sciex (API III+), Micromass (Quattro II), and Finnigan (TSQ 7000), were…”
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The insertion and extrusion of heterosulfur bridges. X. Conversions in the triphenylene-triphenylo[4,5-bcd] thiophene system by Klemm, L. H., Lawrence, Ross F.

“…Sulfur bridging of triphenylene (3) to form triphenylo[4,5‐bcd]thiophene (4) is effected in 18% yield by means of hydrogen sulfide and a molybdena catalyst…”
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Chemical synthesis, absolute configuration, and stereochemistry of formation of 10-hydroxywarfarin: a major oxidative metabolite of (+)-(R)-warfarin from hepatic microsomal preparations by Lawrence, R F, Rettie, A E, Eddy, A C, Trager, W F

“…The synthesis of a diastereomerically pure 10-hydroxywarfarin [4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-1 benzopyran-2-one] was accomplished in three…”
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The insertion and extrusion of heterosulfur bridges. VII. Desulfurization of phenanthro[4,5-bcd]thiophene by means of methanol and a molybdena catalyst by Klemm, L. H., Karchesy, Joseph J., Lawrence, Ross F.

“…Phenanthro[4,5‐bcd]thiophene (1) is converted into phenanthrene (2) (50%) and a mixture of methylphenanthrenes (3) (12%) by means of methanol and a sulfided…”
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The insertion and extrusion of heterosulfur bridges. XI. Desulfurizations of condensed thiophenes by means of methanol and a molybdena catalyst by Klemm, L. H., Karchesy, Joseph J., Lawrence, Ross F., Wang, Pih

“…Desulfurizations of 2‐methyl‐ (1b), 4‐methyl‐ (1c), and 4,6‐dimethyldibenzothiophenes (1d), benzo[b]thiophene (2), and benzo[b]naphtho[2,1‐d]thiophene (5) were…”
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The insertion and extrusion of heterosulfur bridges. XII. Selectivity and side reactions in the bridging process by Klemm, L. H., Pou, Sovitj, Detlefsen, W. D., Higgins, Clay, Lawrence, Ross F.

“…1‐Phenylnaphthalene undergoes sulfur bridging at 500° in the presence of hydrogen sulfide and a heterogeneous catalyst to produce…”
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Comparative chromatographic adsorbabilities of some azines, thioles and thienopyridines, their heteroatom oxides and other derivatives on silica gel by Klemm, L. H., Lee, F. H. W., Lawrence, Ross F.

“…Thin layer chromatographic Rf data on silica gel are reported for 64 compounds containing either a thiole sulfur atom, one or more azine nitrogen atoms, or…”
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