Search Results - "Lawrence, Kevin M."

Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1 by Jones, Rebecca C, Lawrence, Kevin M, Higgins, Scott M, Richardson, Stephen M, Townsend, Paul A

“…Post-traumatic OA (PTOA) is often triggered by injurious, high-impact loading events which result in rapid, excessive chondrocyte cell death and a phenotypic…”
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Geo-Accumulation Index of Manganese in Soils Due to Flooding in Boac and Mogpog Rivers, Marinduque, Philippines with Mining Disaster Exposure by Monjardin, Cris Edward F., Senoro, Delia B., Magbanlac, Jeffersen James M., de Jesus, Kevin Lawrence M., Tabelin, Carlito B., Natal, Pablito M.

“…This paper presents the effects of flooding on the accumulation of manganese (Mn) in soils within proximity of the Boac and Mogpog rivers in Marinduque of The…”
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GIS-Based Risk Assessment of Structure Attributes in Flood Zones of Odiongan, Romblon, Philippines by Gacu, Jerome G., Monjardin, Cris Edward F., de Jesus, Kevin Lawrence M., Senoro, Delia B.

“…Flood triggered by heavy rains and typhoons leads to extensive damage to land and structures putting rural communities in crucial condition. Most of the…”
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Application of Machine Learning for Prediction and Monitoring of Manganese Concentration in Soil and Surface Water by Monjardin, Cris Edward F., Power, Christopher, Senoro, Delia B., De Jesus, Kevin Lawrence M.

“…This study explored the application of machine learning, specifically artificial neural network (ANN), to create prediction models for manganese (Mn)…”
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Neuro-Particle Swarm Optimization Based In-Situ Prediction Model for Heavy Metals Concentration in Groundwater and Surface Water by De Jesus, Kevin Lawrence M, Senoro, Delia B, Dela Cruz, Jennifer C, Chan, Eduardo B

“…Limited monitoring activities to assess data on heavy metal (HM) concentration contribute to worldwide concern for the environmental quality and the degree of…”
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A Hybrid Neural Network–Particle Swarm Optimization Informed Spatial Interpolation Technique for Groundwater Quality Mapping in a Small Island Province of the Philippines by De Jesus, Kevin Lawrence M., Senoro, Delia B., Dela Cruz, Jennifer C., Chan, Eduardo B.

“…Water quality monitoring demands the use of spatial interpolation techniques due to on-ground challenges. The implementation of various spatial interpolation…”
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In Situ Measurements of Domestic Water Quality and Health Risks by Elevated Concentration of Heavy Metals and Metalloids Using Monte Carlo and MLGI Methods by Senoro, Delia B., de Jesus, Kevin Lawrence M., Nolos, Ronnel C., Lamac, Ma. Rowela L., Deseo, Khainah M., Tabelin, Carlito B.

“…The domestic water (DW) quality of an island province in the Philippines that experienced two major mining disasters in the 1990s was assessed and evaluated in…”
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Groundwater Quality Monitoring Using In-Situ Measurements and Hybrid Machine Learning with Empirical Bayesian Kriging Interpolation Method by Senoro, Delia B., de Jesus, Kevin Lawrence M., Mendoza, Leonel C., Apostol, Enya Marie D., Escalona, Katherine S., Chan, Eduardo B.

“…This article discusses the assessment of groundwater quality using a hybrid technique that would aid in the convenience of groundwater (GW) quality monitoring…”
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Quantitative Assessment and Spatial Analysis of Metals and Metalloids in Soil Using the Geo-Accumulation Index in the Capital Town of Romblon Province, Philippines by Senoro, Delia B., Monjardin, Cris Edward F., Fetalvero, Eddie G., Benjamin, Zidrick Ed C., Gorospe, Alejandro Felipe B., de Jesus, Kevin Lawrence M., Ical, Mark Lawrence G., Wong, Jonathan P.

“…The municipality of Romblon in the Philippines is an island known for its marble industry. The subsurface of the Philippines is known for its limestone. The…”
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Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts by Fuller, Karen, Lawrence, Kevin M, Ross, Jade L, Grabowska, Urszula B, Shiroo, Masahiro, Samuelsson, Bertil, Chambers, Timothy J

“…Abstract The coupling between bone formation and resorption creates a therapeutic impasse in osteoporosis: antiresorptive therapy halts bone loss, but also…”
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Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury by McCormick, James, Barry, Sean P, Sivarajah, Ahila, Stefanutti, Giorgio, Townsend, Paul A, Lawrence, Kevin M, Eaton, Simon, Knight, Richard A, Thiemermann, Christoph, Latchman, David S, Stephanou, Anastasis

“…The signal transducer and activator of transcription (STAT) family are latent transcription factors involved in a variety of signal transduction pathways,…”
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New targets of urocortin-mediated cardioprotection by Barry, Seán P, Lawrence, Kevin M, McCormick, James, Soond, Surinder M, Hubank, Mike, Eaton, Simon, Sivarajah, Ahila, Scarabelli, Tiziano M, Knight, Richard A, Thiemermann, Christoph, Latchman, David S, Townsend, Paul A, Stephanou, Anastasis

“…The urocortin (UCN) hormones UCN1 and UCN2 have been shown previously to confer significant protection against myocardial ischaemia/reperfusion (I/R) injury;…”
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Hormone-stimulated modulation of endocytic trafficking in osteoclasts by Stenbeck, Gudrun, Lawrence, Kevin M, Albert, Anthony P

“…A precise control of vesicular trafficking is crucial not only for osteoclastic bone resorption, but also for the crosstalk between osteoclasts and…”
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BAG-1 Proteins Protect Cardiac Myocytes from Simulated Ischemia/Reperfusion-induced Apoptosis via an Alternate Mechanism of Cell Survival Independent of the Proteasome by Townsend, Paul A, Cutress, Ramsey I, Carroll, Christopher J, Lawrence, Kevin M, Scarabelli, Tiziano M, Packham, Graham, Stephanou, Anastasis, Latchman, David S

“…BAG-1 ( B cl-2-associated a thano g ene- 1 ) proteins interact with the HSC70 and HSP70 heat shock proteins and have been proposed to promote cell survival by…”
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Erratum to ‘Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts’ by Fuller, Karen, Lawrence, Kevin M., Ross, Jade L., Grabowska, Urszula B., Shiroo, Masahiro, Samuelsson, Bertil, Chambers, Timothy J.

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Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy by Taylor, Paul D, McConnell, Josie, Khan, Imran Y, Holemans, Kathleen, Lawrence, Kevin M, Asare-Anane, Henry, Persaud, Shanta J, Jones, Peter M, Petrie, Linda, Hanson, Mark A, Poston, Lucilla

“…We previously reported that prenatal and suckling exposure to a maternal diet rich in animal fat leads to cardiovascular dysfunction in young adult rat…”
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Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel by Combs, Charlotte E, Fuller, Karen, Kumar, Hashethra, Albert, Anthony P, Pirianov, Grisha, McCormick, James, Locke, Ian C, Chambers, Timothy J, Lawrence, Kevin M

“…This study investigated the role of urocortin (UCN), a member of the corticotrophin-releasing factor (CRF) family of peptides, in osteoclast maturation and…”
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The cardioprotective agent urocortin induces expression of CT-1 by Janjua, Sadia, Lawrence, Kevin M, Ng, Leong L, Latchman, David S

“…The corticotrophin-releasing hormone-related factor, urocortin (Ucn) and the interleukin (IL)-6 family cytokine cardiotrophin-1 (CT-1) are both…”
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Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen by Owens, Gemma L., Lawrence, Kevin M., Jackson, Tom R., Crosbie, Emma J., Sayan, Berna S., Kitchener, Henry C., Townsend, Paul A.

“…Urocortin (UCN1) peptide shares structural and functional homology with corticotropin‐releasing factor (CRF). UCN1 is significantly reduced in endometrial…”
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The selective PPARγ antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion by Collino, Massimo, Patel, Nimesh S.A., Lawrence, Kevin M., Collin, Marika, Latchman, David S., Yaqoob, Muhammad M., Thiemermann, Christoph

“…The selective PPARγ antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. We have recently reported that pretreatment of…”
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