Search Results - "Lawrence, J. C."

Development and Evaluation of an Enzyme-Linked Immunosorbent Assay for Use in the Detection of Bovine Tuberculosis in Cattle by Waters, W R, Buddle, B M, Vordermeier, H M, Gormley, E, Palmer, M V, Thacker, T C, Bannantine, J P, Stabel, J R, Linscott, R, Martel, E, Milian, F, Foshaug, W, Lawrence, J C

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002 by Brunn, G. J., Williams, J., Sabers, C., Wiederrecht, G., Lawrence, J. C., Abraham, R. T.

“…The immunosuppressant, rapamycin, inhibits cell growth by interfering with the function of a novel kinase, termed mammalian target of rapamycin (mTOR). The…”
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Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin by Brunn, Gregory J., Hudson, Christine C., Sekulić, Aleksandar, Williams, Josie M., Hosoi, Hajime, Houghton, Peter J., Lawrence, John C., Abraham, Robert T.

“…The immunosuppressant rapamycin interferes with G$_1$-phase progression in lymphoid and other cell types by inhibiting the function of the mammalian target of…”
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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function by Pause, Arnim, Belsham, Graham J, Gingras, Anne-Claude, Donzé, Olivier, Lin, Tai-An, Lawrence, John C, Sonenberg, Nahum

“…The cloning is described of two related human complementary DNAs encoding polypeptides that interact specifically with the translation initiation factor…”
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MaizeGDB, the community database for maize genetics and genomics by Lawrence, Carolyn J., Dong, Qunfeng, Polacco, Mary L., Seigfried, Trent E., Brendel, Volker

“…The Maize Genetics and Genomics Database (MaizeGDB) is a central repository for maize sequence, stock, phenotype, genotypic and karyotypic variation, and…”
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A gas entrainment model for hydraulic jumps in near horizontal pipes by Skartlien, R., Julshamn, J.A., Lawrence, C.J., Liu, L.

“…► We model gas entrainment in hydraulic jumps confined by a pipe. ► The experimental gas flow rates were measured directly. ► We find evidence for entrainment…”
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PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation by Lin, Tai-An, Kong, Xianming, Timothy A. J. Haystead, Pause, Arnim, Belsham, Graham, Sonenberg, Nahum, Lawrence, John C.

“…PHAS-I is a heat-stable protein (relative molecular mass $\approx$12,400) found in many tissues. It is rapidly phosphorylated in rat adipocytes incubated with…”
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An ATR−IR Study of Poly (Dimethylsiloxane) under High-Pressure Carbon Dioxide:  Simultaneous Measurement of Sorption and Swelling by Flichy, N. M. B, Kazarian, S. G, Lawrence, C. J, Briscoe, B. J

“…The CO2 sorption and the consequent swelling of un-cross-linked poly (dimethylsiloxane) (PDMS) have been measured simultaneously at high pressure using in-situ…”
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On the interpretation of orifice extrusion data for viscoplastic materials by Basterfield, R.A., Lawrence, C.J., Adams, M.J.

“…An analytical model of orifice extrusion has been developed that allows the material parameters to be derived from experimental data for materials such as…”
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Multiple Mechanisms Control Phosphorylation of PHAS-I in Five (S/T)P Sites That Govern Translational Repression by Mothe-Satney, Isabelle, Yang, Daqing, Fadden, Patrick, Haystead, Timothy A. J., Lawrence, John C.

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Monitoring of Multiphase Pharmaceutical Processes Using Electrical Resistance Tomography by Ricard, F., Brechtelsbauer, C., Xu, X.Y., Lawrence, C.J.

“…Recent developments in the use of non-intrusive, electrical measurements to interrogate mixing processes in batch vessels have triggered a joint GSK/Imperial…”
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Insulin stimulates protein synthesis in skeletal muscle by enhancing the association of eIF-4E and eIF-4G by Kimball, S R, Jurasinski, C V, Lawrence, Jr, J C, Jefferson, L S

“…Insulin stimulated protein synthesis in gastrocnemius muscle of perfused rat hindlimb preparations by approximately twofold. The stimulation of protein…”
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Increasing cAMP Attenuates Activation of Mitogen-Activated Protein Kinase by Sevetson, Bradley R., Kong, Xianming, Lawrence, John C.

“…Activation of the mitogen-activated protein kinase (MAP kinase) isoforms ERK1 and ERK2 was investigated in rat adipocytes. Kinase activities were measured by…”
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PHAS/4E-BPs as regulators of mRNA translation and cell proliferation by Lawrence, John C., Abraham, Robert T.

“…Insulin and growth factors elicit rapid increases in protein synthesis by stimulating mRNA translation. PHAS/4E-BPs, a recently discovered family of…”
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Circulating concentrations of bovine pregnancy-associated glycoproteins and late embryonic mortality in lactating dairy herds by Pohler, K G, Pereira, M H C, Lopes, F R, Lawrence, J C, Keisler, D H, Smith, M F, Vasconcelos, J L M, Green, J A

“…The objectives of these experiments were as follows: (1) to determine the association between circulating concentrations of pregnancy-associated glycoproteins…”
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Surprises of genetic engineering: A possible model of polyglucosan body disease by RABEN, N, DANON, M, DIMAURO, S, PLOTZ, P, LU, N, LEE, E, SHLISELFELD, L, SKURAT, A. V, ROACH, P. J, LAWRENCE, J. C, MUSUMECI, O, SHANSKE, S

“…The authors previously reported the generation of a knockout mouse model of Pompe disease caused by the inherited deficiency of lysosomal acid…”
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Wave regimes in two-layer microchannel flow by Sisoev, G.M., Matar, O.K., Sileri, D., Lawrence, C.J.

“…We consider the dynamics of an interface separating two immiscible fluids in a vertically oriented channel. We use boundary-layer theory together with the…”
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New insights into the role and mechanism of glycogen synthase activation by insulin by J C Lawrence, Jr, P J Roach

“…New insights into the role and mechanism of glycogen synthase activation by insulin. J C Lawrence, Jr and P J Roach Department of Pharmacology, University of…”
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Effects of a single pre‐operative dexmedetomidine dose on isoflurane requirements and peri‐operative haemodynamic stability by Lawrence, C. J., De Lange, S.

“…In a double‐blind, placebo‐controlled study we investigated the effect of a single pre‐induction intravenous dose of dexmedetomidine 2 μg.kg−1 on anaesthetic…”
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Identification of Phosphorylation Sites in the Translational Regulator, PHAS-I, That Are Controlled by Insulin and Rapamycin in Rat Adipocytes by Fadden, P, Haystead, T A, Lawrence, Jr, J C

“…Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase in vitro decreased PHAS-I binding to eukaryotic initiation factor (eIF)-4E. The decrease in…”
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