Search Results - "Lawrence, Dylan J"
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In vivo noninvasive systemic myography of acute systemic vasoactivity in female pregnant mice
Published in Nature communications (09-10-2023)“…Altered vasoactivity is a major characteristic of cardiovascular and oncological diseases, and many therapies are therefore targeted to the vasculature…”
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2
Size-tunable ICG-based contrast agent platform for targeted near-infrared photoacoustic imaging
Published in Photoacoustics (Munich) (01-02-2023)“…Near-infrared photoacoustic imaging (NIR-PAI) combines the advantages of optical and ultrasound imaging to provide anatomical and functional information of…”
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3
Photoacoustic imaging provides an in vivo assessment of the preeclamptic placenta remodeling and function in response to therapy
Published in Placenta (Eastbourne) (01-08-2022)“…There is a lack of effective therapeutic interventions for preeclampsia. A central factor in the etiology of the disease is the development of placental…”
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Spectral photoacoustic imaging to estimate in vivo placental oxygenation during preeclampsia
Published in Scientific reports (24-01-2019)“…Preeclampsia is a pregnancy-related hypertensive disorder accounting for 14% of global maternal deaths annually. Preeclampsia — maternal hypertension and…”
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5
Characterizing a photoacoustic and fluorescence imaging platform for preclinical murine longitudinal studies
Published in Journal of biomedical optics (01-03-2023)“…To effectively study preclinical animal models, medical imaging technology must be developed with a high enough resolution and sensitivity to perform…”
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Sex and the G Protein–Coupled Estrogen Receptor Impact Vascular Stiffness
Published in Hypertension (Dallas, Tex. 1979) (01-07-2021)“…Because arterial stiffness increases following menopause, estrogen may be a protective factor. Our previous work indicates that the GPER (G protein–coupled…”
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Longitudinal characterization of local perfusion of the rat placenta using contrast-enhanced ultrasound imaging
Published in Interface focus (06-10-2019)“…The placenta performs many physiological functions critical for development. Insufficient placental perfusion, due to improper vascular remodelling, has been…”
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Smooth muscle regional contribution to vaginal wall function
Published in Interface focus (06-08-2019)“…Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal canal. In the USA, there is a 12% lifetime risk for requiring…”
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Abstract P208: Imaging The Longitudinal Reduction In Placental Ischemia In Response To Therapeutic Intervention For Preeclampsia
Published in Hypertension (Dallas, Tex. 1979) (01-09-2020)“…Abstract only Preeclampsia is believed to be induced by abnormal vascular remodeling and the resulting placental ischemia during early development. Sildenafil,…”
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10
Sex and the G Protein–Coupled Estrogen Receptor Impact Vascular Stiffness
Published in Hypertension (Dallas, Tex. 1979) (24-05-2021)“…Because arterial stiffness increases following menopause, estrogen may be a protective factor. Our previous work indicates that the GPER (G protein–coupled…”
Get full text
Journal Article -
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Abstract 113: Female Protection From Arterial Stiffness Diminishes With G Protein-Coupled Estrogen Receptor Deletion or Angiotensin II Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-09-2018)“…Abstract only Arterial stiffness independently predicts cardiovascular mortality, coronary events, and stroke in hypertensive subjects and is exacerbated in…”
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Journal Article -
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Longitudinal Multimodal Imaging of in vivo Placental Function during the Onset of Preeclampsia and in Response to Therapeutic Intervention in the Reduced Uterine Perfusion Pressure Rat
Published 01-01-2021“…Preeclampsia is a leading cause of maternal and fetal mortality, affecting up to 8% of pregnancies. Clinically, preeclampsia is diagnosed by the new onset of…”
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Dissertation