Search Results - "Lawlor, K."

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion by Conos, S A, Lawlor, K E, Vaux, D L, Vince, J E, Lindqvist, L M

“…Caspase-1 cleaves and activates the pro-inflammatory cytokine interleukin-1 beta (IL-1 β ), yet the mechanism of IL-1 β release and its dependence on cell…”
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A review of analytical parameters in ‘rapid’ liquid chromatographic methods for bioanalysis: Can we do better? by Lawlor, K, Clausen, J, Johnston, A, Edge, A, Wolff, K, Castrignanò, E, Couchman, L

“…•For many applications there are benefits to be gained in reducing analysis times.•The use of short LC columns (<50 mm) and high flow rates (exceeding 1…”
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TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 by Moujalled, D M, Cook, W D, Okamoto, T, Murphy, J, Lawlor, K E, Vince, J E, Vaux, D L

“…Ligation of tumor necrosis factor receptor 1 (TNFR1) can cause cell death by caspase 8 or receptor-interacting protein kinase 1 (RIPK1)- and RIPK3-dependent…”
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Viral nematics in confined geometries by Manyuhina, O V, Lawlor, K B, Marchetti, M C, Bowick, M J

“…Motivated by recent experiments on the rod-like virus bacteriophage fd, confined to circular and annular domains, we present a theoretical study of structural…”
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Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling by Liu, X., D'Cruz, A.A., Hansen, J., Croker, B.A., Lawlor, K.E., Sims, N.A., Wicks, I.P.

“…To investigate the impact of deleting Suppressor of Cytokine Signaling (SOCS)-3 (SOCS3) in chondrocytes during murine skeletal development. Mice with a…”
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Burnout and well‐being in otolaryngology trainees: A systematic review by Lawlor, Skye K., Low, Christopher M., Carlson, Matthew L., Rajasekaran, Karthik, Choby, Garret

“…Objective To comprehensively review the recent published literature to characterize current trends of burnout and well‐being among otolaryngology trainees…”
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Medical Students' Perception of Plastic Surgery by Shaharan, S, Joyce, C W, Lawlor, K, Joyce, K, Kelly, J L

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Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3 by Liu, X, Liu, R, Croker, B.A, Lawlor, K.E, Smyth, G.K, Wicks, I.P

“…Summary Objective To describe gene expression in murine chondrocytes stimulated with IL-6 family cytokines and the impact of deleting Suppressor of Cytokine…”
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Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice by Vandenberg, C J, Josefsson, E C, Campbell, K J, James, C, Lawlor, K E, Kile, B T, Cory, S

“…Bax and Bak are critical effectors of apoptosis. Although both are widely expressed and usually functionally redundant, recent studies suggest that Bak has…”
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Severe inflammatory arthritis and lymphadenopathy in the absence of TNF by Campbell, I K, O'Donnell, K, Lawlor, K E, Wicks, I P

“…It has been postulated that TNF has a pivotal role in a cytokine cascade that results in joint inflammation and destruction in rheumatoid arthritis (RA). To…”
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A qualitative study of the physical, social and attitudinal environments influencing the participation of children with cerebral palsy in northeast England by Lawlor, K., Mihaylov, S., Welsh, B., Jarvis, S., Colver, A.

“…Purpose: The social model of disability considers participation to be determined by the social, attitudinal and physical environments experienced by an…”
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Changes in the microbial community of an arable soil caused by long-term metal contamination by Abaye, D.A, Lawlor, K, Hirsch, P.R, Brookes, P.C

“…Summary The effects of past applications of farmyard manure (FYM, applied from 1942 to 1967), metal‐contaminated sewage sludge (applied from 1942 to 1961) and…”
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Defining clinically significant tumor size in vestibular schwannoma to inform timing of microsurgery during wait-and-scan management: moving beyond minimum detectable growth by Macielak, Robert J, Wallerius, Katherine P, Lawlor, Skye K, Lohse, Christine M, Marinelli, John P, Neff, Brian A, Van Gompel, Jamie J, Driscoll, Colin L W, Link, Michael J, Carlson, Matthew L

“…Detection of vestibular schwannoma (VS) growth during observation leads to definitive treatment at most centers globally. Although ≥ 2 mm represents an…”
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Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints by Hahn, Rebecca T, Lawlor, Matthew K, Davidson, Charles J, Badhwar, Vinay, Sannino, Anna, Spitzer, Ernest, Lurz, Philipp, Lindman, Brian R, Topilsky, Yan, Baron, Suzanne J, Chadderdon, Scott, Khalique, Omar K, Tang, Gilbert H L, Taramasso, Maurizio, Grayburn, Paul A, Badano, Luigi, Leipsic, Jonathon, Lindenfeld, JoAnn, Windecker, Stephan, Vemulapalli, Sreekanth, Redfors, Bjorn, Alu, Maria C, Cohen, David J, Rodés-Cabau, Josep, Ailawadi, Gorav, Mack, Michael, Ben-Yehuda, Ori, Leon, Martin B, Hausleiter, Jörg

“…Abstract Interest in the pathophysiology, etiology, management, and outcomes of patients with tricuspid regurgitation (TR) has grown in the wake of multiple…”
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Soil Solid‐Phase Controls Lead Activity in Soil Solution by Badawy, S. H., Helal, M. I. D., Chaudri, A. M., Lawlor, K., McGrath, S. P.

“…ABSTRACT Lead pollution of the environment is synonymous with civilization. It has no known biological function, and is naturally present in soil, but its…”
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Baseline Characteristics and Clinical Outcomes of a Tricuspid Regurgitation Referral Population by Lawlor, Matthew K., Ng, Vivian, Ahmed, Shaan, Dershowitz, Lyle, Brener, Michael I., Kampaktsis, Polydoros, Pitts, Amy, Vahl, Torsten, Nazif, Tamim, Leon, Martin, George, Isaac, Hahn, Rebecca T., Kodali, Susheel

“…Adverse outcomes in tricuspid regurgitation (TR) have been associated with advanced regurgitation severity and right-sided cardiac remodeling, and late…”
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Hearing Preservation Microsurgery in Vestibular Schwannomas: Worth Attempting in “Larger” Tumors? by Wallerius, Katherine P., Macielak, Robert J., Lawlor, Skye K., Lohse, Christine M., Neff, Brian A., Van Gompel, Jamie J., Driscoll, Colin L. W., Link, Michael J., Carlson, Matthew L.

“…Objectives/Hypothesis To review hearing preservation after microsurgical resection of sporadic vestibular schwannomas according to tumor size. Study Design…”
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Right ventricular remodeling and clinical outcomes following transcatheter tricuspid valve intervention by Dershowitz, Lyle, Lawlor, Matthew K., Hamid, Nadira, Kampaktsis, Polydoros, Ning, Yuming, Vahl, Torsten P., Nazif, Tamim, Khalique, Omar, Ng, Vivian, Kurlansky, Paul, Leon, Martin, Hahn, Rebecca, Kodali, Susheel, George, Isaac

“…Aims Characterize the impact of residual tricuspid regurgitation (TR) on right ventricle (RV) remodeling and clinical outcomes after transcatheter tricuspid…”
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The Effect of Age on Facial Nerve Recovery After Vestibular Schwannoma Resection by Macielak, Robert J., Lohse, Christine M., Wallerius, Katherine P., Lawlor, Skye K., Neff, Brian A., Celda, Maria Peris, Van Gompel, Jamie J., Driscoll, Colin L.W., Link, Michael J., Carlson, Matthew L.

“…The objective of this study is to assess the influence of age on facial nerve recovery after microsurgical resection of sporadic vestibular schwannoma. A…”
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Soil solid-phase controls lead activity in soil solution by Badawy, S.H, Helal, M.I.D, Chaudri, A.M, Lawlor, K, McGrath, S.P

“…Lead pollution of the environment is synonymous with civilization. It has no known biological function, and is naturally present in soil, but its presence in…”
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