Search Results - "Law, Melissa"
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A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings
Published in Annals of internal medicine (01-07-2022)“…A substantial proportion of persons who develop COVID-19 report persistent symptoms after acute illness. Various pathophysiologic mechanisms have been…”
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Eosinophil-Associated Processes Underlie Differences in Clinical Presentation of Loiasis Between Temporary Residents and Those Indigenous to Loa-Endemic Areas
Published in Clinical infectious diseases (01-01-2015)“…Background. Loa loa has emerged as an important public health problem due to the occurrence of immune-mediated severe posttreatment reactions following…”
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Investigation of the Importance of Protein 3D Structure for Assessing Conservation of Lysine Acetylation Sites in Protein Homologs
Published in Frontiers in microbiology (31-01-2022)“…Acetylation is a protein post-translational modification (PTM) that can affect a variety of cellular processes. In bacteria, two PTM ε-acetylation mechanisms…”
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Phase 1 trial to model primary, secondary, and tertiary dengue using a monovalent vaccine
Published in BMC infectious diseases (23-05-2023)“…The four co-circulating and immunologically interactive dengue virus serotypes (DENV1-4) pose a unique challenge to vaccine design because sub-protective…”
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Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness
Published in Blood (15-06-2003)“…Since serum tryptase levels are elevated in some patients with myeloproliferative disorders, we examined their utility in identifying a subset of patients with…”
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Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing
Published in Blood (15-11-2007)“…Although imatinib is clearly the treatment of choice for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia (CEL), little is known about optimal dosing,…”
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Filariasis in travelers presenting to the GeoSentinel Surveillance Network
Published in PLoS neglected tropical diseases (01-12-2007)“…As international travel increases, there is rising exposure to many pathogens not traditionally encountered in the resource-rich countries of the world…”
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Safety and efficacy of the monoclonal anti–interleukin-5 antibody SCH55700 in the treatment of patients with hypereosinophilic syndrome
Published in Blood (15-04-2004)“…Four patients with hypereosinophilic syndrome (HES) refractory to or intolerant of treatment with conventional therapy were treated with a single 1 mg/kg dose…”
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Citrate Anticoagulant Improves the Sensitivity of Borreliella (Borrelia) burgdorferi Plasma Culture
Published in Journal of clinical microbiology (01-11-2017)Get full text
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Quiescent Innate Response to Infective Filariae by Human Langerhans Cells Suggests a Strategy of Immune Evasion
Published in Infection and Immunity (01-05-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti–IL-5 antibody SCH55700
Published in Journal of Allergy and Clinical Immunology (01-12-2004)“…Hypereosinophilic syndrome and eosinophilic gastroenteritis with peripheral eosinophilia are characterized by sustained eosinophilia and eosinophil-mediated…”
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Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface
Published in The Journal of immunology (1950) (15-05-2004)“…To assess the physiologic interactions between the infective stage of Brugia malayi--one of the extracellular parasites responsible for lymphatic filariasis in…”
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Familial eosinophilia: a benign disorder?
Published in Blood (01-06-2004)“…Familial eosinophilia (FE) is an autosomal dominant disorder characterized by marked eosinophilia and progression to end organ damage in some, but not all,…”
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A Conserved Tyrosine Residue of EcSpeG is Absolutely Critical for Enzymatic Activity
Published in The FASEB journal (01-04-2020)“…Abstract only The Spermine/Spermidine N ‐acetyltransferase from Escherichia coli (EcSpeG) is an allosteric dodecameric enzyme that belongs to the Gcn5‐related…”
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Generating enzyme and radical‐mediated bisubstrates as tools for investigating Gcn5‐related N‐acetyltransferases
Published in FEBS letters (01-08-2017)“…Gcn5‐related N‐acetyltransferases (GNATs) are found in all kingdoms of life and catalyze important acyl transfer reactions in diverse cellular processes. While…”
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PA4794 Gcn5‐related N‐acetyltransferase bisubstrate inhibitors and mechanistic insights from co‐crystal structures, site‐directed mutants, and molecular dynamics
Published in The FASEB journal (01-04-2017)“…Abstract only…”
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Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
Published in Blood (15-01-2004)“…We recently described a subset of patients with a myeloproliferative variant of hypereosinophilic syndrome (MHES) characterized by elevated serum tryptase…”
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Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes
Published in ACS infectious diseases (10-02-2017)“…Modification of aminoglycosides by N-acetyltransferases (AACs) is one of the major mechanisms of resistance to these antibiotics in human bacterial pathogens…”
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