Search Results - "Law, Jonathan P."

Coronary microvascular dysfunction: a key step in the development of uraemic cardiomyopathy? by Radhakrishnan, Ashwin, Pickup, Luke C, Price, Anna M, Law, Jonathan P, Edwards, Nicola C, Steeds, Richard P, Ferro, Charles J, Townend, Jonathan N

“…The syndrome of uraemic cardiomyopathy, characterised by left ventricular hypertrophy, diffuse fibrosis and systolic and diastolic dysfunction, is common in…”
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Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype by Hall, Caitlin, Law, Jonathan P., Reyat, Jasmeet S., Cumberland, Max J., Hang, Shaun, Vo, Nguyen T. N., Raniga, Kavita, Weston, Chris J., O’Shea, Christopher, Townend, Jonathan N., Gehmlich, Katja, Ferro, Charles J., Denning, Chris, Pavlovic, Davor

“…Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and…”
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Quantification of fibroblast growth factor 23 and N-terminal pro-B-type natriuretic peptide to identify patients with atrial fibrillation using a high-throughput platform: A validation study by Chua, Winnie, Law, Jonathan P, Cardoso, Victor R, Purmah, Yanish, Neculau, Georgiana, Jawad-Ul-Qamar, Muhammad, Russell, Kalisha, Turner, Ashley, Tull, Samantha P, Nehaj, Frantisek, Brady, Paul, Kastner, Peter, Ziegler, André, Gkoutos, Georgios V, Pavlovic, Davor, Ferro, Charles J, Kirchhof, Paulus, Fabritz, Larissa

“…Large-scale screening for atrial fibrillation (AF) requires reliable methods to identify at-risk populations. Using an experimental semi-quantitative biomarker…”
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Acute kidney injury is more common in men than women after accounting for socioeconomic status, ethnicity, alcohol intake and smoking history by Loutradis, Charalampos, Pickup, Luke, Law, Jonathan P, Dasgupta, Indranil, Townend, Jonathan N, Cockwell, Paul, Sharif, Adnan, Sarafidis, Pantelis, Ferro, Charles J

“…The association of several comorbidities, including diabetes mellitus, hypertension, cardiovascular disease, heart failure and chronic kidney or liver disease,…”
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Early renal function trajectories, cytomegalovirus serostatus and long-term graft outcomes in kidney transplant recipients by Law, Jonathan P, Borrows, Richard, McNulty, David, Sharif, Adnan, Ferro, Charles J

“…Improved recognition of factors influencing graft survival has led to better short-term kidney transplant outcomes. However, efforts to prevent long-term graft…”
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Clinical Potential of Targeting Fibroblast Growth Factor-23 and αKlotho in the Treatment of Uremic Cardiomyopathy by Law, Jonathan P, Price, Anna M, Pickup, Luke, Radhakrishnan, Ashwin, Weston, Chris, Jones, Alan M, McGettrick, Helen M, Chua, Winnie, Steeds, Richard P, Fabritz, Larissa, Kirchhof, Paulus, Pavlovic, Davor, Townend, Jonathan N, Ferro, Charles J

“…Chronic kidney disease is highly prevalent, affecting 10% to 15% of the adult population worldwide and is associated with increased cardiovascular morbidity…”
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Coronary microvascular dysfunction is associated with degree of anaemia in end-stage renal disease by Radhakrishnan, Ashwin, Pickup, Luke C, Price, Anna M, Law, Jonathan P, McGee, Kirsty C, Fabritz, Larissa, Senior, Roxy, Steeds, Richard P, Ferro, Charles J, Townend, Jonathan N

“…Coronary microvascular dysfunction (CMD) is common in end-stage renal disease (ESRD) and is an adverse prognostic marker. Coronary flow velocity reserve (CFVR)…”
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Changes in left ventricular structure and function associated with renal transplantation: a systematic review and meta‐analysis by Pickup, Luke C., Law, Jonathan P., Radhakrishnan, Ashwin, Price, Anna M., Loutradis, Charalampos, Smith, Toby O., Edwards, Nicola C., Steeds, Richard P., Townend, Jonathan N., Ferro, Charles J.

“…Aims This study aimed to examine if the cardiac changes associated with uraemic cardiomyopathy are reversed by renal transplantation. Methods and results…”
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Hypertension and cardiomyopathy associated with chronic kidney disease: epidemiology, pathogenesis and treatment considerations by Law, Jonathan P., Pickup, Luke, Pavlovic, Davor, Townend, Jonathan N., Ferro, Charles J.

“…Chronic kidney disease (CKD) is a complex condition with a prevalence of 10–15% worldwide. An inverse-graded relationship exists between cardiovascular events…”
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Sudden cardiac death in chronic renal disease: aetiology and risk reduction strategies by Pickup, Luke C, Law, Jonathan P, Townend, Jonathan N, Ferro, Charles J

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The effect of admission and pre-admission serum creatinine as baseline to assess incidence and outcomes of acute kidney injury in acute medical admissions by Pickup, Luke, Loutradis, Charalampos, Law, Jonathan P, Arnold, Julia J, Dasgupta, Indranil, Sarafidis, Pantelis, Townend, Jonathan N, Cockwell, Paul, Ferro, Charles J

“…Abstract Background Acute kidney injury (AKI) in hospital-admitted patients is a common complication associated with increased mortality. The diagnosis of AKI…”
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Impact of socioeconomic deprivation on the development of diabetic retinopathy: a population-based, cross-sectional and longitudinal study over 12 years by Low, Liying, Law, Jonathan P, Hodson, James, McAlpine, Ritchie, O'Colmain, Una, MacEwen, Caroline

“…Objective To study the association between socioeconomic deprivation and prevalence of diabetic retinopathy (DR). Design Population-based, cross-sectional…”
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Anticoagulant strategies for the patient with chronic kidney disease by Law, Jonathan P, Pickup, Luke, Townend, Jonathan N, Ferro, Charles J

“…Chronic kidney disease (CKD) is a global health problem affecting up to 14% of the adult population in developed countries. On the basis of current guidelines,…”
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Dialysis Following Transcatheter Aortic Valve Replacement: Risk Factors and Outcomes: An Analysis From the UK TAVI (Transcatheter Aortic Valve Implantation) Registry by Ferro, Charles J, Law, Jonathan P, Doshi, Sagar N, de Belder, Mark, Moat, Neil, Mamas, Mamas, Hildick-Smith, David, Ludman, Peter, Townend, Jonathan N

“…This study sought to determine the risk factors for post-transcatheter aortic valve replacement (TAVR) dialysis and to determine the impact of pre-TAVR or…”
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Vive les Differences!-A case for optimism in the treatment of patients with heart failure and preserved ejection fraction? by Law, Jonathan P, Pickup, Luke, Townend, Jonathan N, Ferro, Charles J

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Cardiovascular Effects of Unilateral Nephrectomy in Living Kidney Donors at 5 Years by Price, Anna M., Moody, William E., Stoll, Victoria M., Vijapurapu, Ravi, Hayer, Manvir K., Biasiolli, Luca, Weston, Chris J., Webster, Rachel, Wesolowski, Roman, McGee, Kirsty C., Liu, Boyang, Baig, Shanat, Pickup, Luke C., Radhakrishnan, Ashwin, Law, Jonathan P., Edwards, Nicola C., Steeds, Richard P., Ferro, Charles J., Townend, Jonathan N.

“…Kidney donation reduces renal function by ≈30% allowing study of the cardiovascular effects of a reduced estimated glomerular filtration rate without…”
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Coronary flow velocity reserve and inflammatory markers in living kidney donors by Radhakrishnan, Ashwin, Price, Anna M., Pickup, Luke C., Law, Jonathan P., McGee, Kirsty C., Fabritz, Larissa, Senior, Roxy, Steeds, Richard P., Ferro, Charles J., Townend, Jonathan N.

“…Coronary microvascular dysfunction is prevalent in chronic kidney disease (CKD), and may contribute to the development of myocardial dysfunction in CKD…”
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Changes in Blood Pressure and Arterial Hemodynamics following Living Kidney Donation by Price, Anna M, Greenhall, George H B, Moody, William E, Steeds, Richard P, Mark, Patrick B, Edwards, Nicola C, Hayer, Manvir K, Pickup, Luke C, Radhakrishnan, Ashwin, Law, Jonathan P, Banerjee, Debasish, Campbell, Tunde, Tomson, Charles R V, Cockcroft, John R, Shrestha, Badri, Wilkinson, Ian B, Tomlinson, Laurie A, Ferro, Charles J, Townend, Jonathan N

“…The Effect of a Reduction in GFR after Nephrectomy on Arterial Stiffness and Central Hemodynamics (EARNEST) study was a multicenter, prospective, controlled…”
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Dialysis Following Transcatheter Aortic Valve Replacement: Risk Factors and Outcomes by Ferro, Charles J., Law, Jonathan P., Doshi, Sagar N., de Belder, Mark, Moat, Neil, Mamas, Mamas, Hildick-Smith, David, Ludman, Peter, Townend, Jonathan N.

“…This study sought to determine the risk factors for post-transcatheter aortic valve replacement (TAVR) dialysis and to determine the impact of pre-TAVR or…”
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Differential pattern of RP1 mutations in retinitis pigmentosa by Zhang, Xin, Chen, Li Jia, Law, Jonathan P, Lai, Timothy Y Y, Chiang, Sylvia W Y, Tam, Pancy O S, Chu, Kwan Yi, Wang, Ningli, Zhang, Mingzhi, Pang, Chi Pui

“…Retinitis pigmentosa 1 (RP1) is a major gene responsible for both autosomal dominant and autosomal recessive retinitis pigmentosa (RP). We have previously…”
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