Search Results - "Law, Ivy Ka Man"

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    MiR-21 in Substance P-induced exosomes promotes cell proliferation and migration in human colonic epithelial cells by Bakirtzi, Kyriaki, Man Law, Ivy Ka, Fang, Kai, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

    “…Exosomes are cellular vesicles involved in intercellular communication via their specialized molecular cargo, such as miRNAs. Substance P (SP), a…”
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    Role and mechanisms of exosomal miRNAs in IBD pathophysiology by Wani, Sameena, Man Law, Ivy Ka, Pothoulakis, Charalabos

    “…Exosomes represent secretory membranous vesicles used for the information exchange between cells and organ-to-organ communication. Exosome crosstalk mechanisms…”
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    Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice by Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Mukhopadhyay, Riya, Xie, Ying, Law, Ivy Ka Man, Shih, David Q., Mattai, S. Anjani, Li, Zhaoping, Koon, Hon Wai

    Published in Scientific reports (30-07-2020)
    “…Elafin is an antimicrobial and anti-inflammatory protein. We hypothesize that elafin expression correlates with diabetes. Among non-diabetic and prediabetic…”
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    P127 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN REGULATES COLONIC EPITHELIAL CELL MIGRATION AND IS CRUCIAL TO EMBRYONIC DEVELOPMENT by Law, Ivy Ka Man, Pothoulakis, Charalabos

    Published in Inflammatory bowel diseases (07-02-2019)
    “…Abstract Background Colonic epithelium forms a selective barrier between lumen and colonic mucosa. The integrity of colonic epithelium is maintained by cell…”
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    P123 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN MAINTAINS COLONIC EPITHELIAL PERMEABILITY AND MUCOSAL INTEGRITY THROUGH BETA CATENIN DURING INFLAMMATION by Law, Ivy Ka Man, Pothoulakis, Charalabos

    Published in Inflammatory bowel diseases (18-01-2018)
    “…Abstract Background Barrier function of colonic epithelium is compromised in IBD patients and contributes to colonic inflammation. Previously, we showed that…”
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    14 COLONIC EPITHELIAL CELL-SPECIFIC AFTIPHILIN KNOCKDOWN REGULATES EPITHELIAL BARRIER FUNCTION THROUGH MYOSIN LIGHT CHAIN-ASSOCIATED ACTIN ORGANIZATION IN VITRO AND INTESTINAL LENGTH IN VIVO by Man Law, Ivy Ka, Rankin, Carl, Pothoulakis, Charalabos

    Published in Inflammatory bowel diseases (23-01-2020)
    “…Abstract Background and Aims Colonic epithelial integrity is often compromised during colonic inflammation and Inflammatory Bowel Disease. Aftiphilin (AFTPH)…”
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    Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis by Law, Ivy Ka Man, Bakirtzi, Kyriaki, Polytarchou, Christos, Oikonomopoulos, Angelos, Hommes, Daniel, Iliopoulos, Dimitrios, Pothoulakis, Charalabos

    Published in Gut (01-07-2015)
    “…Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial…”
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    Journal Article