Search Results - "Law, Ivy Ka Man"
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A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation
Published in American journal of physiology: Gastrointestinal and liver physiology (01-09-2016)“…High-throughput technologies revealed new categories of genes, including the long noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease;…”
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MiR-21 in Substance P-induced exosomes promotes cell proliferation and migration in human colonic epithelial cells
Published in American journal of physiology: Gastrointestinal and liver physiology (01-12-2019)“…Exosomes are cellular vesicles involved in intercellular communication via their specialized molecular cargo, such as miRNAs. Substance P (SP), a…”
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Role and mechanisms of exosomal miRNAs in IBD pathophysiology
Published in American journal of physiology: Gastrointestinal and liver physiology (01-12-2020)“…Exosomes represent secretory membranous vesicles used for the information exchange between cells and organ-to-organ communication. Exosome crosstalk mechanisms…”
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Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice
Published in Scientific reports (30-07-2020)“…Elafin is an antimicrobial and anti-inflammatory protein. We hypothesize that elafin expression correlates with diabetes. Among non-diabetic and prediabetic…”
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Identification of novel mRNAs and lncRNAs associated with mouse experimental colitis and human inflammatory bowel disease
Published in American journal of physiology: Gastrointestinal and liver physiology (01-11-2018)“…Inflammatory bowel disease (IBD) is a complex disorder that is associated with significant morbidity. While many recent advances have been made with new…”
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P127 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN REGULATES COLONIC EPITHELIAL CELL MIGRATION AND IS CRUCIAL TO EMBRYONIC DEVELOPMENT
Published in Inflammatory bowel diseases (07-02-2019)“…Abstract Background Colonic epithelium forms a selective barrier between lumen and colonic mucosa. The integrity of colonic epithelium is maintained by cell…”
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Molecular characterization of Coriolus versicolor PSP-induced apoptosis in human promyelotic leukemic HL-60 cells using cDNA microarray
Published in International journal of oncology (01-08-2005)“…Proteins and peptide bound polysaccharides (PSP) extracted from Basidiomycetous fungi are widely used in cancer immunotherapy and recently demonstrated to…”
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P123 THE TRANS-GOLGI NETWORK PROTEIN AFTIPHILIN MAINTAINS COLONIC EPITHELIAL PERMEABILITY AND MUCOSAL INTEGRITY THROUGH BETA CATENIN DURING INFLAMMATION
Published in Inflammatory bowel diseases (18-01-2018)“…Abstract Background Barrier function of colonic epithelium is compromised in IBD patients and contributes to colonic inflammation. Previously, we showed that…”
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14 COLONIC EPITHELIAL CELL-SPECIFIC AFTIPHILIN KNOCKDOWN REGULATES EPITHELIAL BARRIER FUNCTION THROUGH MYOSIN LIGHT CHAIN-ASSOCIATED ACTIN ORGANIZATION IN VITRO AND INTESTINAL LENGTH IN VIVO
Published in Inflammatory bowel diseases (23-01-2020)“…Abstract Background and Aims Colonic epithelial integrity is often compromised during colonic inflammation and Inflammatory Bowel Disease. Aftiphilin (AFTPH)…”
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Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis
Published in Gut (01-07-2015)“…Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial…”
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