Search Results - "Law, Henry C. H."

An optimized co-immunoprecipitation protocol for the analysis of endogenous protein-protein interactions in cell lines using mass spectrometry by Lagundžin, Dragana, Krieger, Kimiko L., Law, Henry C.-H., Woods, Nicholas T.

“…This protocol represents an optimized proteomics-based protocol for the endogenous protein enrichment and protein-protein interaction analysis. This 2-step…”
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The Proteomic Landscape of Pancreatic Ductal Adenocarcinoma Liver Metastases Identifies Molecular Subtypes and Associations with Clinical Response-Response by Law, Henry C-H, Clement, Emalie J, Grandgenett, Paul M, Hollingsworth, Michael A, Woods, Nicholas T

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Goldfish spexin: solution structure and novel function as a satiety factor in feeding control by Wong, Matthew K H, Sze, Kong Hung, Chen, Ting, Cho, Chi Kong, Law, Henry C H, Chu, Ivan K, Wong, Anderson O L

“…Spexin (SPX) is a neuropeptide identified recently by bioinformatic approach. At present not much is known about its biological actions, and comparative…”
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Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy by Zhang, Zaijun, Zhang, Gaoxiao, Sun, Yewei, Szeto, Samuel S. W., Law, Henry C. H., Quan, Quan, Li, Guohui, Yu, Pei, Sho, Eiketsu, Siu, Michael K. W., Lee, Simon M. Y., Chu, Ivan K., Wang, Yuqiang

“…TBN, a novel tetramethylpyrazine derivative armed with a powerful free radical-scavenging nitrone moiety, has been reported to reduce cerebral infarction in…”
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Delineating the role of FANCA in glucose-stimulated insulin secretion in β cells through its protein interactome by Lagundžin, Dragana, Hu, Wen-Feng, Law, Henry C H, Krieger, Kimiko L, Qiao, Fangfang, Clement, Emalie J, Drincic, Andjela T, Nedić, Olgica, Naldrett, Michael J, Alvarez, Sophie, Woods, Nicholas T

“…Hyperinsulinemia affects 72% of Fanconi anemia (FA) patients and an additional 25% experience lowered glucose tolerance or frank diabetes. The underlying…”
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Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia by Law, Henry C. H, Szeto, Samuel S. W, Quan, Quan, Zhao, Yun, Zhang, Zaijun, Krakovska, Olga, Lui, Leong Ting, Zheng, Chengyou, Lee, Simon M.-Y, Siu, K. W. Michael, Wang, Yuqiang, Chu, Ivan K

“…Stroke is one of the main causes of mortality and long-term disability worldwide. The pathophysiological mechanisms underlying this disease are not well…”
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Implementation of a multiple‐fraction concatenation strategy in an online two‐dimensional high‐/low‐pH reversed‐phase/reversed‐phase liquid chromatography platform for qualitative and quantitative shotgun proteomic analyses by Law, Henry C.H., Kong, Ricky P.W., Li, Mengzhu, Szeto, Samuel S.W., Chu, Ivan K.

“…Multidimensional liquid chromatography is the mainstay separation technique used for shotgun proteomic analyses. The application of a multiple‐fraction…”
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Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs by Qiao, Fangfang, Law, Henry C-H, Krieger, Kimiko L, Clement, Emalie J, Xiao, Yi, Buckley, Shannon M, Woods, Nicholas T

“…RNA polymerase II subunit A Carboxy-Terminal Domain Phosphatase 1 (CTDP1), a member of the haloacid dehalogenase superfamily phosphatases, has a defined role…”
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Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax by King, Hannah M., Rana, Sandeep, Kubica, Sydney P., Mallareddy, Jayapal Reddy, Kizhake, Smitha, Ezell, Edward L., Zahid, Muhammad, Naldrett, Michael J., Alvarez, Sophie, Law, Henry C.-H., Woods, Nicholas T., Natarajan, Amarnath

“…[Display omitted] Cyclin-dependent kinase 9 (CDK9) is a member of the cyclin-dependent kinase (CDK) family which is involved in transcriptional regulation of…”
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The Proteomic Landscape of Pancreatic Ductal Adenocarcinoma Liver Metastases Identifies Molecular Subtypes and Associations with Clinical Response by Law, Henry C-H, Lagundžin, Dragana, Clement, Emalie J, Qiao, Fangfang, Wagner, Zachary S, Krieger, Kimiko L, Costanzo-Garvey, Diane, Caffrey, Thomas C, Grem, Jean L, DiMaio, Dominick J, Grandgenett, Paul M, Cook, Leah M, Fisher, Kurt W, Yu, Fang, Hollingsworth, Michael A, Woods, Nicholas T

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease that can be separated into distinct subtypes based on molecular signatures. Identifying…”
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UBR5 HECT domain mutations identified in mantle cell lymphoma control maturation of B cells by Swenson, Samantha A., Gilbreath, Tyler J., Vahle, Heather, Hynes-Smith, R. Willow, Graham, Jared H., Law, Henry C.-H., Amador, Catalina, Woods, Nicholas T., Green, Michael R., Buckley, Shannon M.

“…Coordination of a number of molecular mechanisms including transcription, alternative splicing, and class switch recombination are required to facilitate…”
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Combined Alcohol Exposure and KRAS Mutation in Human Pancreatic Ductal Epithelial Cells Induces Proliferation and Alters Subtype Signatures Determined by Multi-Omics Analysis by Clement, Emalie J, Law, Henry C-H, Qiao, Fangfang, Noe, Dragana, Trevino, Jose G, Woods, Nicholas T

“…Pancreatic Ductal adenocarcinoma (PDAC) is an aggressive cancer commonly exhibiting KRAS-activating mutations. Alcohol contributes to the risk of developing…”
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Online coupling of hydrophilic interaction/strong cation exchange/reversed-phase liquid chromatography with porous graphitic carbon liquid chromatography for simultaneous proteomics and N-glycomics analysis by Zhao, Yun, Law, Henry C.H., Zhang, Zaijun, Lam, Herman C., Quan, Quan, Li, Guohui, Chu, Ivan K.

“…•Online three-dimensional liquid chromatography for simultaneous proteomics and N-glycoproteomics.•First N-glycoproteomics analysis of cynomolgus monkey…”
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Fully Automated Multidimensional Reversed-Phase Liquid Chromatography with Tandem Anion/Cation Exchange Columns for Simultaneous Global Endogenous Tyrosine Nitration Detection, Integral Membrane Protein Characterization, and Quantitative Proteomics Mapping in Cerebral Infarcts by Quan, Quan, Szeto, Samuel S. W., Law, Henry C. H., Zhang, Zaijun, Wang, Yuqiang, Chu, Ivan K.

“…Protein tyrosine nitration (PTN) is a signature hallmark of radical-induced nitrative stress in a wide range of pathophysiological conditions, with naturally…”
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A versatile reversed phase-strong cation exchange-reversed phase (RP-SCX-RP) multidimensional liquid chromatography platform for qualitative and quantitative shotgun proteomics by Law, Henry C H, Kong, Ricky P W, Szeto, Samuel S W, Zhao, Yun, Zhang, Zaijun, Wang, Yuqiang, Li, Guohui, Quan, Quan, Lee, Simon M Y, Lam, Herman C, Chu, Ivan K

“…An automatable, robust, high-performance online multidimensional liquid chromatography (MDLC) platform comprising of pH 10 reversed-phase (RP), strong cation…”
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Abstract PO-005: Proteome profiling of pancreatic ductal adenocarcinoma (PDAC) primary tumors in Caucasian, African American and Latinx patients by Law, Henry C. H., Riner, Andrea N., Trevino, Jose G., Woods, Nicholas T.

“…Abstract The clinical management of pancreatic ductal adenocarcinoma (PDAC) faces difficult challenges due to its aggressive metastatic potential, complex…”
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Abstract PO-127: Proteome profiling of pancreatic Ductal Adenocarcinoma (PDAC) primary tumors in Caucasian, African Americans and Latinx patients by Law, Henry C.-H., Riner, Andrea N., Trevino, Jose G., Woods, Nicholas T.

“…Abstract The clinical management of pancreatic ductal adenocarcinoma (PDAC) faces difficult challenges due to its aggressive metastatic potential, complex…”
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Abstract B090: Evaluating the molecular determinants of PDAC racial health disparities by Johansen-Sallee, Anthony E, Barber, Alexa M, Law, Henry C.-H., Vudatha, Vignesh, Trevino, Jose, Woods, Nicholas T

“…Abstract Pancreatic cancer is the 3rd leading cause of cancer-related deaths, with a 5-year survival rate of just 13%. Pancreatic ductal adenocarcinoma (PDAC),…”
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Delineating the role of FANCA in glucose-stimulated insulin secretion in [beta] cells through its protein interactome by Lagundzin, Dragana, Hu, Wen-Feng, Law, Henry C. H, Krieger, Kimiko L, Qiao, Fangfang, Clement, Emalie J, Drincic, Andjela T, Nedic, Olgica, Naldrett, Michael J, Alvarez, Sophie, Woods, Nicholas T

“…Hyperinsulinemia affects 72% of Fanconi anemia (FA) patients and an additional 25% experience lowered glucose tolerance or frank diabetes. The underlying…”
Get full text