Search Results - "Law, Andy"
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Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton
Published in Neoplasia (New York, N.Y.) (01-04-2017)“…Abstract A set of high-affinity, high-specificity posttranslational modification (PTM) enrichment tools was developed to generate an unbiased snapshot of four…”
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Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study
Published in PLoS medicine (31-01-2023)“…Immunocompromised patients may be at higher risk of mortality if hospitalised with Coronavirus Disease 2019 (COVID-19) compared with immunocompetent patients…”
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Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology
Published in PloS one (05-08-2009)“…The dissection of complex traits of economic importance to the pig industry requires the availability of a significant number of genetic markers, such as…”
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Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19
Published in Scientific reports (18-12-2020)“…The increasing body of literature describing the role of host factors in COVID-19 pathogenesis demonstrates the need to combine diverse, multi-omic data to…”
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GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen
Published in PLoS pathogens (01-12-2023)“…The advances in gene editing bring unprecedented opportunities in high throughput functional genomics to animal research. Here we describe a genome wide CRISPR…”
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Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen
Published in Viruses (01-02-2024)“…To identify host factors that affect Bovine Herpes Virus Type 1 (BoHV-1) infection we previously applied a genome wide CRISPR knockout screen targeting all…”
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Decreased expression of the satiety signal receptor CCKAR is responsible for increased growth and body weight during the domestication of chickens
Published in American journal of physiology: endocrinology and metabolism (01-05-2013)“…Animal domestication has resulted in changes in growth and size. It has been suggested that this may have involved selection for differences in appetite…”
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Cementless Total Hip Replacement in 20 Juveniles Using BFX™ Arthroplasty
Published in Veterinary surgery (01-08-2014)“…OBJECTIVE: To describe outcome after a minimum of 1 year for total hip replacement (THR) using BioMedtrix BFX™ biologic fixation implants in skeletally…”
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Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa
Published in Viruses (01-04-2024)“…Lumpy skin disease virus (LSDV) is a member of the capripoxvirus (CPPV) genus of the family. LSDV is a rapidly emerging, high-consequence pathogen of cattle,…”
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10
An introduction to scripting in Ruby for biologists
Published in BMC bioinformatics (16-07-2009)“…The Ruby programming language has a lot to offer to any scientist with electronic data to process. Not only is the initial learning curve very shallow, but its…”
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Biomechanical Testing and Histologic Examination of Intradermal Skin Closure in Dogs Using Barbed Suture Device and Non‐Barbed Monofilament Suture
Published in Veterinary surgery (01-01-2017)“…Objective To compare the biomechanical strength and histologic features of 3‐0 Glycomer™ 631 barbed suture (V‐LOC™ 90 Absorbable Wound Closure Device,…”
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An XML transfer schema for exchange of genomic and genetic mapping data: implementation as a web service in a Taverna workflow
Published in BMC bioinformatics (14-08-2009)“…Genomic analysis, particularly for less well-characterized organisms, is greatly assisted by performing comparative analyses between different types of genome…”
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13
The Chicken Gene Nomenclature Committee report
Published in BMC genomics (14-07-2009)“…Comparative genomics is an essential component of the post-genomic era. The chicken genome is the first avian genome to be sequenced and it will serve as a…”
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Genomic analysis reveals extensive gene duplication within the bovine TRB locus
Published in BMC genomics (24-04-2009)“…Diverse TR and IG repertoires are generated by V(D)J somatic recombination. Genomic studies have been pivotal in cataloguing the V, D, J and C genes present in…”
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A Microsatellite Linkage Map of the European Sea Bass Dicentrarchus labrax L
Published in Genetics (Austin) (01-08-2005)“…A genetic linkage map of the European sea bass (Dicentrarchus labrax) was constructed from 174 microsatellite markers, including 145 new markers reported in…”
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The dynamics of chromosome evolution in birds and mammals
Published in Nature (London) (25-11-1999)“…Comparative mapping, which compares the location of homologous genes in different species, is a powerful tool for studying genome evolution. Comparative maps…”
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A second generation radiation hybrid map to aid the assembly of the bovine genome sequence
Published in BMC genomics (06-11-2006)“…Several approaches can be used to determine the order of loci on chromosomes and hence develop maps of the genome. However, all mapping approaches are prone to…”
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Evaluation of approaches for identifying population informative markers from high density SNP chips
Published in BMC genetics (13-05-2011)“…Genetic markers can be used to identify and verify the origin of individuals. Motivation for the inference of ancestry ranges from conservation genetics to…”
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ArkMAP: integrating genomic maps across species and data sources
Published in BMC bioinformatics (13-08-2013)“…The visualisation of genetic and genomic maps aligned within and between species and across data sources can be used to inform studies of genome evolution,…”
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Molecular cloning, characterization, and chromosomal assignment of porcine cationic amino acid transporter-1
Published in Genomics (San Diego, Calif.) (01-03-2005)“…We have cloned and characterized the gene encoding the porcine cationic amino acid transporter, member 1 (CAT-1) (HGMW-approved gene symbol SLC7A1) from…”
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