Search Results - "Lavrik, N."

Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model by Schleich, Kolja, Warnken, Uwe, Fricker, Nicolai, Öztürk, Selcen, Richter, Petra, Kammerer, Kerstin, Schnölzer, Martina, Krammer, Peter H., Lavrik, Inna N.

“…The CD95 (Fas/APO-1) death-inducing signaling complex (DISC) is essential for the initiation of CD95-mediated apoptotic and nonapoptotic responses. The CD95…”
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Modulation of CD95-mediated signaling by post-translational modifications: towards understanding CD95 signaling networks by Seyrek, Kamil, Lavrik, Inna N.

“…CD95 is a member of the death receptor family and is well-known to promote apoptosis. However, accumulating evidence indicates that in some context CD95 has…”
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Apoptosis regulation by subcellular relocation of caspases by Prokhorova, Evgeniia A., Kopeina, Gelina S., Lavrik, Inna N., Zhivotovsky, Boris

“…The cleavage of nuclear proteins by caspases promotes nuclear breakdown and, therefore, plays a key role in apoptosis execution. However, the detailed…”
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Role of the nucleus in apoptosis: signaling and execution by Prokhorova, Evgeniia A, Zamaraev, Alexey V, Kopeina, Gelina S, Zhivotovsky, Boris, Lavrik, Inna N

“…Since their establishment in the early 1970s, the nuclear changes upon apoptosis induction, such as the condensation of chromatin, disassembly of nuclear…”
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Controlling Cell Death through Post-translational Modifications of DED Proteins by Seyrek, Kamil, Ivanisenko, Nikita V., Richter, Max, Hillert, Laura K., König, Corinna, Lavrik, Inna N.

“…Apoptosis is a form of programmed cell death, deregulation of which occurs in multiple disorders, including neurodegenerative and autoimmune diseases as well…”
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Cellular FLICE-like inhibitory proteins (c-FLIPs): Fine-tuners of life and death decisions by Öztürk, Selcen, Schleich, Kolja, Lavrik, Inna N.

“…c-FLIP proteins (isoforms: c-FLIPL, c-FLIPS, and c-FLIPR) play an essential role in the regulation of death receptor (DR)-induced apoptosis and NF-κB…”
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A guide to automated apoptosis detection: How to make sense of imaging flow cytometry data by Pischel, Dennis, Buchbinder, Jörn H, Sundmacher, Kai, Lavrik, Inna N, Flassig, Robert J

“…Imaging flow cytometry is a powerful experimental technique combining the strength of microscopy and flow cytometry to enable high-throughput characterization…”
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Long and short isoforms of c-FLIP act as control checkpoints of DED filament assembly by Hillert, Laura K., Ivanisenko, Nikita V., Espe, Johannes, König, Corinna, Ivanisenko, Vladimir A., Kähne, Thilo, Lavrik, Inna N.

“…The assembly of the death-inducing signaling complex (DISC) and death effector domain (DED) filaments at CD95/Fas initiates extrinsic apoptosis. Procaspase-8…”
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Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL by Fricker, Nicolai, Beaudouin, Joel, Richter, Petra, Eils, Roland, Krammer, Peter H, Lavrik, Inna N

“…Cellular FADD-like interleukin-1β-converting enzyme inhibitory proteins (c-FLIPs; isoforms c-FLIP long [c-FLIPL], c-FLIP short [c-FLIPS], and c-FLIP Raji…”
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Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity by Matthess, Yves, Raab, Monika, Sanhaji, Mourad, Lavrik, Inna N., Strebhardt, Klaus

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Editorial: Dynamical Networks of Life/Death Decisions in a Cell: From DNA Repair to Cell Death by Lavrik, Inna N.

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Post-translational Modification of Caspases: The Other Side of Apoptosis Regulation by Zamaraev, Alexey V, Kopeina, Gelina S, Prokhorova, Evgeniia A, Zhivotovsky, Boris, Lavrik, Inna N

“…Apoptosis is a crucial program of cell death that controls development and homeostasis of multicellular organisms. The main initiators and executors of this…”
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The Crosstalk of Apoptotic and Non-Apoptotic Signaling in CD95 System by Seyrek, Kamil, Espe, Johannes, Reiss, Elisabeth, Lavrik, Inna N

“…The mechanisms of CD95 (Fas/APO-1)-mediated extrinsic apoptotic pathway in cancer cells have been extensively studied. The majority of human cells express…”
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Nanotechnology and chip level systems for pressure driven liquid chromatography and emerging analytical separation techniques: A review by Lavrik, N.V., Taylor, L.T., Sepaniak, M.J.

“…Pressure driven liquid chromatography (LC) is a powerful and versatile separation technique particularly suitable for differentiating species present in…”
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The role of death domain proteins in host response upon SARS-CoV-2 infection: modulation of programmed cell death and translational applications by Ivanisenko, Nikita V., Seyrek, Kamil, Kolchanov, Nikolay A., Ivanisenko, Vladimir A., Lavrik, Inna N.

“…The current pandemic of novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) poses a significant global public health threat. While urgent…”
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Quantitative single cell analysis uncovers the life/death decision in CD95 network by Buchbinder, Jörn H, Pischel, Dennis, Sundmacher, Kai, Flassig, Robert J, Lavrik, Inna N

“…CD95/Fas/APO-1 is a member of the death receptor family that triggers apoptotic and anti-apoptotic responses in particular, NF-κB. These responses are…”
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Optically read Coriolis vibratory gyroscope based on a silicon tuning fork by Lavrik, N. V., Datskos, P. G.

“…In this work, we describe the design, fabrication, and characterization of purely mechanical miniature resonating structures that exhibit gyroscopic…”
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c-FLIPR, a New Regulator of Death Receptor-induced Apoptosis by Golks, Alexander, Brenner, Dirk, Fritsch, Cornelius, Krammer, Peter H., Lavrik, Inna N.

“…c-FLIPs (c-FLICE inhibitory proteins) play an essential role in regulation of death receptor-induced apoptosis. Multiple splice variants of c-FLIP have been…”
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Ally or traitor: the dual role of p62 in caspase-2 regulation by Volik, Pavel I., Zamaraev, Alexey V., Egorshina, Aleksandra Y., Pervushin, Nikolay V., Kapusta, Anastasia A., Tyurin-Kuzmin, Pyotr A., Lipatova, Anastasia V., Kaehne, Thilo, Lavrik, Inna N., Zhivotovsky, Boris, Kopeina, Gelina S.

“…Caspase-2 is a unique and conserved cysteine protease that is involved in several cellular processes, including different forms of cell death, maintenance of…”
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Caspases: pharmacological manipulation of cell death by Lavrik, Inna N, Golks, Alexander, Krammer, Peter H

“…Caspases, a family of cysteine proteases, play a central role in apoptosis. During the last decade, major progress has been made to further understand caspase…”
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