Search Results - "Lavorgna, Giovanni"

The Microbiome of the Prostate Tumor Microenvironment by Cavarretta, Ilaria, Ferrarese, Roberto, Cazzaniga, Walter, Saita, Diego, Lucianò, Roberta, Ceresola, Elisa R, Locatelli, Irene, Visconti, Laura, Lavorgna, Giovanni, Briganti, Alberto, Nebuloni, Manuela, Doglioni, Claudio, Clementi, Massimo, Montorsi, Francesco, Canducci, Filippo, Salonia, Andrea

“…Abstract Background The advent of molecular-based methods of identification and characterization of complex microbial populations has led to a new era of…”
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A virus-free cellular model recapitulates several features of severe COVID-19 by Lavorgna, Giovanni, Cavalli, Giulio, Dagna, Lorenzo, Gregori, Silvia, Larcher, Alessandro, Landoni, Giovanni, Ciceri, Fabio, Montorsi, Francesco, Salonia, Andrea

“…As for all newly-emergent pathogens, SARS-CoV-2 presents with a relative paucity of clinical information and experimental models, a situation hampering both…”
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Identification of novel sense and antisense transcription at the TRPM2 locus in cancer by Orfanelli, Ugo, Wenke, Ann-Kathrin, Doglioni, Claudio, Russo, Vincenzo, Bosserhoff, Anja Katrin, Lavorgna, Giovanni

“…It has been proposed that in cancer, where the bulk of the genome becomes hypomethylated, there is an increase in transcriptional noise that might lead to the…”
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A mechanistic insight into the anti-metastatic role of the prostate specific antigen by Pellegrino, Francesco, Coghi, Arianna, Lavorgna, Giovanni, Cazzaniga, Walter, Guazzoni, Edoardo, Locatelli, Irene, Villa, Isabella, Bolamperti, Simona, Finocchio, Nadia, Alfano, Massimo, Lucianò, Roberta, Briganti, Alberto, Montorsi, Francesco, Salonia, Andrea, Cavarretta, Ilaria

“…•Prostate specific antigen is the standard circulating biomarker for prostate cancer.•We provide novel evidence that collagen 1 is an additional substrate for…”
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Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development by Lenti, Elisa, Farinello, Diego, Yokoyama, Kazunari K, Penkov, Dmitry, Castagnaro, Laura, Lavorgna, Giovanni, Wuputra, Kenly, Sandell, Lisa L, Tjaden, Naomi E Butler, Bernassola, Francesca, Caridi, Nicoletta, De Antoni, Anna, Wagner, Michael, Kozinc, Katja, Niederreither, Karen, Blasi, Francesco, Pasini, Diego, Majdic, Gregor, Tonon, Giovanni, Trainor, Paul A, Brendolan, Andrea

“…The molecular mechanisms that underlie spleen development and congenital asplenia, a condition linked to increased risk of overwhelming infections, remain…”
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Complex Loci in human and mouse genomes by Engström, Pär G, Suzuki, Harukazu, Ninomiya, Noriko, Akalin, Altuna, Sessa, Luca, Lavorgna, Giovanni, Brozzi, Alessandro, Luzi, Lucilla, Tan, Sin Lam, Yang, Liang, Kunarso, Galih, Ng, Edwin Lian-Chong, Batalov, Serge, Wahlestedt, Claes, Kai, Chikatoshi, Kawai, Jun, Carninci, Piero, Hayashizaki, Yoshihide, Wells, Christine, Bajic, Vladimir B, Orlando, Valerio, Reid, James F, Lenhard, Boris, Lipovich, Leonard

“…Mammalian genomes harbor a larger than expected number of complex loci, in which multiple genes are coupled by shared transcribed regions in antisense…”
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Single-cell transcriptome profiling reveals several LncRNAs differentially expressed in idiopathic germ cell aplasia by Lavorgna, Giovanni, Tascini, Anna Sofia, Bertini, Alessandro, Lanzaro, Francesco, Montorsi, Francesco, Alfano, Massimo, Salonia, Andrea

“…Mechanisms underlying severe male infertility are still largely elusive. However, recently, a single-cell transcription study by our group identified several…”
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Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell by Lavorgna, Giovanni, Chiacchiera, Fulvio, Briganti, Alberto, Montorsi, Francesco, Pasini, Diego, Salonia, Andrea

“…We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the…”
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The Otx2 Homeoprotein Regulates Expression from the Gonadotropin-Releasing Hormone Proximal Promoter by Kelley, Carolyn G, Lavorgna, Giovanni, Clark, Melody E, Boncinelli, Edoardo, Mellon, Pamela L

“…The GnRH gene is expressed exclusively in a highly restricted population of approximately 800 neurons in the mediobasal hypothalamus in the mouse. The Otx2…”
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Re: Hung-Ming Lam, Holly M. Nguyen, Mark P. Labrecque, et al. Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts. Eur Urol 2020;77:144–55 by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Re: Tea's Value as a Cancer Therapy is Steeped in Uncertainty by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Long non-coding RNAs as novel therapeutic targets in cancer by Lavorgna, Giovanni, Vago, Riccardo, Sarmini, Mohamad, Montorsi, Francesco, Salonia, Andrea, Bellone, Matteo

“…[Display omitted] Thanks to impressive technology advancements, pervasive expression of non-coding RNAs (ncRNAs) has been recently identified in the genome of…”
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Re: Exercise and Cancer Treatment: Balancing Patient Needs. Lancet Oncol 2018;19:715: Cancer Prevention and Treatment: More than Exercising by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Re: Jinjing Chen, Ilaria Guccini, Diletta Di Mitri, et al. Compartmentalized Activities of the Pyruvate Dehydrogenase Complex Sustain Lipogenesis in Prostate Cancer. Nat Genet 2018;50:219–28: Lipid Metabolism in Prostate Cancer: Expanding Patient Therapeutic Opportunities by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Re: Exercise and Cancer Treatment: Balancing Patient Needs. Lancet Oncol 2018;19:715 by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Re: Jinjing Chen, Ilaria Guccini, Diletta Di Mitri, et al. Compartmentalized Activities of the Pyruvate Dehydrogenase Complex Sustain Lipogenesis in Prostate Cancer. Nat Genet 2018;50:219–28 by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Surnames in Y-Chromosome–related Diseases: A New Tool for the Urologist? by Lavorgna, Giovanni, Vago, Riccardo, Montorsi, Francesco, Salonia, Andrea

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Re: Ken J. Kron, Alexander Murison, Stanley Zhou, et al. TMPRSS2–ERG Fusion Co-opts Master Transcription Factors and Activates NOTCH Signaling in Primary Prostate Cancer. Nat Genet 2017;49:1336–45 by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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Noncoding RNA synthesis and loss of Polycomb group repression accompanies the colinear activation of the human HOXA cluster by Sessa, Luca, Breiling, Achim, Lavorgna, Giovanni, Silvestri, Laura, Casari, Giorgio, Orlando, Valerio

“…The ratio of noncoding to protein coding DNA rises with the complexity of the organism, culminating in nearly 99% of nonprotein coding DNA in humans…”
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Prognostic marker and target in prostate cancer by Lavorgna, Giovanni, Montorsi, Francesco, Salonia, Andrea

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