Search Results - "Lavallée‐Adam, Mathieu"

Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress by Vasam, Goutham, Nadeau, Rachel, Cadete, Virgilio J. J., Lavallée‐Adam, Mathieu, Menzies, Keir J., Burelle, Yan

“…Mitochondria share attributes of vesicular transport with their bacterial ancestors given their ability to form mitochondrial‐derived vesicles (MDVs). MDVs are…”
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A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity by Cloutier, Philippe, Lavallée-Adam, Mathieu, Faubert, Denis, Blanchette, Mathieu, Coulombe, Benoit

“…Methylation is a post-translational modification that can affect numerous features of proteins, notably cellular localization, turnover, activity, and…”
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PIGNON: a protein–protein interaction-guided functional enrichment analysis for quantitative proteomics by Nadeau, Rachel, Byvsheva, Anastasiia, Lavallée-Adam, Mathieu

“…Abstract Background Quantitative proteomics studies are often used to detect proteins that are differentially expressed across different experimental…”
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A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy by Chitiprolu, Maneka, Jagow, Chantal, Tremblay, Veronique, Bondy-Chorney, Emma, Paris, Geneviève, Savard, Alexandre, Palidwor, Gareth, Barry, Francesca A., Zinman, Lorne, Keith, Julia, Rogaeva, Ekaterina, Robertson, Janice, Lavallée-Adam, Mathieu, Woulfe, John, Couture, Jean-François, Côté, Jocelyn, Gibbings, Derrick

“…Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while ALS-linked mutations…”
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Proximity Interactome Map of the Vac14–Fig4 Complex Using BioID by Qiu, Shirley, Lavallée-Adam, Mathieu, Côté, Marceline

“…Conversion between phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate on endosomal membranes is critical for the maturation of early…”
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Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry for Top-Down Characterization of Pyrococcus furiosus Proteins on a Proteome Scale by Han, Xuemei, Wang, Yueju, Aslanian, Aaron, Bern, Marshall, Lavallée-Adam, Mathieu, Yates, John R

“…Intact protein analysis via top-down mass spectrometry (MS) provides the unique capability of fully characterizing protein isoforms and combinatorial…”
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Studying the Temporal Dynamics of the Gut Microbiota Using Metabolic Stable Isotope Labeling and Metaproteomics by Smyth, Patrick, Zhang, Xu, Ning, Zhibin, Mayne, Janice, Moore, Jasmine Isabelle, Walker, Krystal, Lavallée-Adam, Mathieu, Figeys, Daniel

“…The gut microbiome and its metabolic processes are dynamic systems. Surprisingly, our understanding of gut microbiome dynamics is limited. Here, we report a…”
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PSEA-Quant: A Protein Set Enrichment Analysis on Label-Free and Label-Based Protein Quantification Data by Lavallée-Adam, Mathieu, Rauniyar, Navin, McClatchy, Daniel B, Yates, John R

“…The majority of large-scale proteomics quantification methods yield long lists of quantified proteins that are often difficult to interpret and poorly…”
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Proteomic and Metaproteomic Approaches to Understand Host–Microbe Interactions by Starr, Amanda E, Deeke, Shelley A, Li, Leyuan, Zhang, Xu, Daoud, Rachid, Ryan, James, Ning, Zhibin, Cheng, Kai, Nguyen, Linh V. H, Abou-Samra, Elias, Lavallée-Adam, Mathieu, Figeys, Daniel

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Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli by Baijal, Kanchi, Abramchuk, Iryna, Herrera, Carmen M, Mah, Thien-Fah, Trent, M Stephen, Lavallée-Adam, Mathieu, Downey, Michael

“…Polyphosphates (polyP) are chains of inorganic phosphates that can reach over 1,000 residues in length. In Escherichia coli, polyP is produced by the polyP…”
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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers by Sanders, Shaun S, Martin, Dale D O, Butland, Stefanie L, Lavallée-Adam, Mathieu, Calzolari, Diego, Kay, Chris, Yates, 3rd, John R, Hayden, Michael R

“…Palmitoylation involves the reversible posttranslational addition of palmitate to cysteines and promotes membrane binding and subcellular localization. Recent…”
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Ddp1 Cooperates with Ppx1 to Counter a Stress Response Initiated by Nonvacuolar Polyphosphate by McCarthy, Liam, Abramchuk, Iryna, Wafy, Gamal, Denoncourt, Alix, Lavallée-Adam, Mathieu, Downey, Michael

“…In diverse cells from bacterial to mammalian species, inorganic phosphate is stored in long chains called polyphosphate (polyP). These nearly universal…”
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Computational Identification of Human Biological Processes and Protein Sequence Motifs Putatively Targeted by SARS-CoV‑2 Proteins Using Protein–Protein Interaction Networks by Nadeau, Rachel, Shahryari Fard, Soroush, Scheer, Amit, Hashimoto-Roth, Emily, Nygard, Dallas, Abramchuk, Iryna, Chung, Yun-En, Bennett, Steffany A. L, Lavallée-Adam, Mathieu

“…While the COVID-19 pandemic is causing important loss of life, knowledge of the effects of the causative SARS-CoV-2 virus on human cells is currently limited…”
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MealTime-MS: A Machine Learning-Guided Real-Time Mass Spectrometry Analysis for Protein Identification and Efficient Dynamic Exclusion by Pelletier, Alexander R, Chung, Yun-En, Ning, Zhibin, Wong, Nora, Figeys, Daniel, Lavallée-Adam, Mathieu

“…Mass spectrometry-based proteomics technologies are prime methods for the high-throughput identification of proteins in complex biological samples…”
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Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function by Kim, Jean J, Savas, Jeffrey N, Miller, Meghan T, Hu, Xindao, Carromeu, Cassiano, Lavallée-Adam, Mathieu, Freitas, Beatriz C G, Muotri, Alysson R, Yates, 3rd, John R, Ghosh, Anirvan

“…Rett syndrome (RTT) is a pervasive developmental disorder caused by mutations in MECP2. Complete loss of MECP2 function in males causes congenital…”
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Modeling Contaminants in AP-MS/MS Experiments by Lavallée-Adam, Mathieu, Cloutier, Philippe, Coulombe, Benoit, Blanchette, Mathieu

“…Identification of protein−protein interactions (PPI) by affinity purification (AP) coupled with tandem mass spectrometry (AP-MS/MS) produces large data sets…”
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Proteomics INTegrator (PINT): An Online Tool To Store, Query, and Visualize Large Proteomics Experiment Results by Martínez-Bartolomé, Salvador, Bamberger, Tom Casimir, Lavallée-Adam, Mathieu, McClatchy, Daniel B, Yates, John R

“…The characterization of complex biological systems based on high-throughput protein quantification through mass spectrometry commonly involves differential…”
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Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology by Savas, Jeffrey N., Wang, Yi-Zhi, DeNardo, Laura A., Martinez-Bartolome, Salvador, McClatchy, Daniel B., Hark, Timothy J., Shanks, Natalie F., Cozzolino, Kira A., Lavallée-Adam, Mathieu, Smukowski, Samuel N., Park, Sung Kyu, Kelly, Jeffery W., Koo, Edward H., Nakagawa, Terunaga, Masliah, Eliezer, Ghosh, Anirvan, Yates, John R.

“…Amyloid beta (Aβ) peptides impair multiple cellular pathways and play a causative role in Alzheimer’s disease (AD) pathology, but how the brain proteome is…”
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The Protein Interaction Network of the Human Transcription Machinery Reveals a Role for the Conserved GTPase RPAP4/GPN1 and Microtubule Assembly in Nuclear Import and Biogenesis of RNA Polymerase II by Forget, Diane, Lacombe, Andrée-Anne, Cloutier, Philippe, Al-Khoury, Racha, Bouchard, Annie, Lavallée-Adam, Mathieu, Faubert, Denis, Jeronimo, Célia, Blanchette, Mathieu, Coulombe, Benoit

“…RNA polymerase II (RNAPII), the 12-subunit enzyme that synthesizes all mRNAs and several non-coding RNAs in eukaryotes, plays a central role in cell function…”
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A functional ecological network based on metaproteomics responses of individual gut microbiomes to resistant starches by Li, Leyuan, Ryan, James, Ning, Zhibin, Zhang, Xu, Mayne, Janice, Lavallée-Adam, Mathieu, Stintzi, Alain, Figeys, Daniel

“…[Display omitted] Resistant starches (RS) are dietary compounds processed by the gut microbiota into metabolites, such as butyrate, that are beneficial to the…”
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