Search Results - "Lauw, Susan"

Pectin methylesterase activity is required for RALF1 peptide signalling output by Rößling, Ann-Kathrin, Dünser, Kai, Liu, Chenlu, Lauw, Susan, Rodriguez-Franco, Marta, Kalmbach, Lothar, Barbez, Elke, Kleine-Vehn, Jürgen

“…The extracellular matrix plays an integrative role in cellular responses in plants, but its contribution to the signalling of extracellular ligands largely…”
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A new silicon phthalocyanine dye induces pyroptosis in prostate cancer cells during photoimmunotherapy by Wolf, Isis, Storz, Jonas, Schultze-Seemann, Susanne, Esser, Philipp R., Martin, Stefan F., Lauw, Susan, Fischer, Peer, Peschers, Marie, Melchinger, Wolfgang, Zeiser, Robert, Gorka, Oliver, Groß, Olaf, Gratzke, Christian, Brückner, Reinhard, Wolf, Philipp

“…Photoimmunotherapy (PIT) combines the specificity of antibodies with the cytotoxicity of light activatable photosensitizers (PS) and is a promising new cancer…”
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Cross-talk between Type Three Secretion System and Metabolism in Yersinia by Schmid, Annika, Neumayer, Wibke, Trülzsch, Konrad, Israel, Lars, Imhof, Axel, Roessle, Manfred, Sauer, Guido, Richter, Susanna, Lauw, Susan, Eylert, Eva, Eisenreich, Wolfgang, Heesemann, Jürgen, Wilharm, Gottfried

“…Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and…”
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Pectin methylesterase activity is required for RALF1 peptide signalling output by Rößling, Ann-Kathrin, Dünser, Kai, Liu, Chenlu, Lauw, Susan, Rodriguez-Franco, Marta, Kalmbach, Lothar, Barbez, Elke, Kleine-Vehn, Jürgen

“…The extracellular matrix plays an integrative role in cellular responses in plants, but its contribution to the signalling of extracellular ligands largely…”
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Photoimmunotherapy of Prostate Cancer With Antibody and Fab Fragments Targeting the Prostate Specific Membrane Antigen by Waibel, Sarah, Graf, Nele, Storz, Jonas, Schultze-Seemann, Susanne, Lauw, Susan, Gratzke, Christian, Brückner, Reinhard, Wolf, Philipp, Wolf, Isis

“…The standard treatment for localized prostate cancer involves surgical removal of the prostate with curative intent. However, when tumor cells persist in the…”
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Antibody-dye Conjugates Targeting EGFR and HER2 for the Photoimmunotherapy of Bladder Cancer by Huber, Fabian, Wolf, Isis, Storz, Jonas, Schultze-Seemann, Susanne, Lauw, Susan, Klemenz, Lukas, Miernik, Arkadiusz, Gratzke, Christian, Brückner, Reinhard, Wolf, Philipp

“…Although there are curative treatment options for non-muscle-invasive bladder cancer, the recurrence of this tumor is high. Therefore, novel targeted therapies…”
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Photoimmunotherapy of HER2-expressing Breast Cancer Cells by Klemenz, Lukas, Wolf, Isis, Storz, Jonas, Schultze-Seemann, Susanne, Gratzke, Christian, Lauw, Susan, Brückner, Reinhard, Wolf, Philipp

“…Breast cancer (BC) is the most common malignant disease worldwide. Localized stages of BC can be successfully treated by surgery. However, local recurrence…”
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Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties by Lan, Chenyang, Stulz, Anja, Barthes, Nicolas P F, Lauw, Susan, Salavei, Pavel, Jung, Manfred, Heerklotz, Heiko, Ulbrich, Maximilian H

“…Many membrane proteins utilize dimerization to transmit signals across the cell membrane regulation of the lateral binding affinity. The complexity of natural…”
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Biosynthesis of isoprenoids – studies on the mechanism of 2C‐methyl‐d‐erythritol‐4‐phosphate synthase by Lauw, Susan, Illarionova, Victoria, Bacher, Adelbert, Rohdich, Felix, Eisenreich, Wolfgang

“…2C‐Methyl‐d‐erythritol‐4‐phosphate synthase, encoded by the ispC gene (also designated dxr), catalyzes the first committed step in the nonmevalonate isoprenoid…”
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Thiazolopyrimidine Inhibitors of 2-Methylerythritol 2,4-Cyclodiphosphate Synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum by Geist, Julie G., Lauw, Susan, Illarionova, Victoria, Illarionov, Boris, Fischer, Markus, Gräwert, Tobias, Rohdich, Felix, Eisenreich, Wolfgang, Kaiser, Johannes, Groll, Michael, Scheurer, Christian, Wittlin, Sergio, Alonso-Gómez, José L., Schweizer, W. Bernd, Bacher, Adelbert, Diederich, François

“…A library of 40 000 compounds was screened for inhibitors of 2‐methylerythritol 2,4‐cyclodiphosphate synthase (IspF) protein from Arabidopsis thaliana using a…”
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Isoprenoid biosynthesis in plants – 2C‐methyl‐d‐erythritol‐4‐phosphate synthase (IspC protein) of Arabidopsis thaliana by Rohdich, Felix, Lauw, Susan, Kaiser, Johannes, Feicht, Richard, Köhler, Peter, Bacher, Adelbert, Eisenreich, Wolfgang

“…The ispC gene of Arabidopsis thaliana was expressed in pseudomature form without the putative plastid‐targeting sequence in a recombinant Escherichia coli…”
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Biosynthesis of isoprenoids – studies on the mechanism of 2 C ‐methyl‐ d ‐erythritol‐4‐phosphate synthase by Lauw, Susan, Illarionova, Victoria, Bacher, Adelbert, Rohdich, Felix, Eisenreich, Wolfgang

“…2 C ‐Methyl‐ d ‐erythritol‐4‐phosphate synthase, encoded by the isp C gene (also designated dxr ), catalyzes the first committed step in the nonmevalonate…”
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Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl- d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery by Sgraja, Tanja, Alphey, Magnus S, Ghilagaber, Stephanos, Marquez, Rudi, Robertson, Murray N, Hemmings, Jennifer L, Lauw, Susan, Rohdich, Felix, Bacher, Adelbert, Eisenreich, Wolfgang, Illarionova, Victoria, Hunter, William N

“…4-Diphosphocytidyl-2C-methyl- d-erythritol kinase (IspE) catalyses the ATP-dependent conversion of 4-diphosphocytidyl-2C-methyl- d-erythritol (CDPME) to…”
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Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis by Hirsch, Anna K H, Alphey, Magnus S, Lauw, Susan, Seet, Michael, Barandun, Luzi, Eisenreich, Wolfgang, Rohdich, Felix, Hunter, William N, Bacher, Adelbert, Diederich, François

“…Enzymes of the non-mevalonate pathway for isoprenoid biosynthesis are therapeutic targets for the treatment of important infectious diseases. Whereas this…”
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Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy by Crane, Christine M., Kaiser, Johannes, Ramsden, Nicola L., Lauw, Susan, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

“…Designed inhibitors (like 1) of IspF, a key enzyme in the non‐mevalonate pathway for terpene biosynthesis and a potential antimalarial target, were synthesized…”
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Structure-Based Design and Synthesis of the First Weak Non-Phosphate Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway of Isoprenoid Biosynthesis by Baumgartner, Corinne, Eberle, Christian, Diederich, François, Lauw, Susan, Rohdich, Felix, Eisenreich, Wolfgang, Bacher, Adelbert

“…In this paper, we describe the structure‐based design, synthesis, and biological evaluation of cytosine derivatives and analogues that inhibit IspF, an enzyme…”
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Nonphosphate Inhibitors of IspE Protein, a Kinase in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy by Hirsch, Anna K. H., Lauw, Susan, Gersbach, Philipp, Schweizer, W. Bernd, Rohdich, Felix, Eisenreich, Wolfgang, Bacher, Adelbert, Diederich, François

“…IspE kinase inhibitors. The first inhibitors for the kinase IspE, an enzyme of the non‐mevalonate pathway, are presented. The nonphosphate based inhibitors…”
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Cross-talk between Type Three Secretion System and Metabolism in YersiniaS by Schmid, Annika, Neumayer, Wibke, Trülzsch, Konrad, Israel, Lars, Imhof, Axel, Roessle, Manfred, Sauer, Guido, Richter, Susanna, Lauw, Susan, Eylert, Eva, Eisenreich, Wolfgang, Heesemann, Jürgen, Wilharm, Gottfried

“…Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and…”
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Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis by Crane, Christine M., Hirsch, Anna K. H., Alphey, Magnus S., Sgraja, Tanja, Lauw, Susan, Illarionova, Victoria, Rohdich, Felix, Eisenreich, Wolfgang, Hunter, William N., Bacher, Adelbert, Diederich, François

“…The enzymes of the non‐mevalonate pathway for isoprenoid biosynthesis are attractive targets for the development of novel drugs against malaria and…”
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Isoprenoid biosynthesis in plants – 2 C ‐methyl‐ d ‐erythritol‐4‐phosphate synthase (IspC protein) of Arabidopsis thaliana by Rohdich, Felix, Lauw, Susan, Kaiser, Johannes, Feicht, Richard, Köhler, Peter, Bacher, Adelbert, Eisenreich, Wolfgang

“…The ispC gene of Arabidopsis thaliana was expressed in pseudomature form without the putative plastid‐targeting sequence in a recombinant Escherichia coli…”
Get full text