Search Results - "Laursen, Alex L."

Mortality and cause of death in persons with chronic hepatitis B virus infection versus healthy persons from the general population in Denmark by Bollerup, Signe, Hallager, Sofie, Engsig, Frederik, Mocroft, Amanda, Krarup, Henrik, Madsen, Lone G., Thielsen, Peter, Balslev, Ulla, Mens, Helene, Barfod, Toke S., Clausen, Mette R., Hobolth, Lise, Laursen, Alex L., Tarp, Britta, Roege, Birgit T., Hansen, Jesper B., Mygind, Lone, Christensen, Peer B., Gerstoft, Jan, Weis, Nina

“…The study aimed to determine adjusted all‐cause mortality and cause of death in persons with chronic hepatitis B virus (HBV) infection compared with age‐ and…”
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Comparison of bone and renal effects in HIV-infected adults switching to abacavir or tenofovir based therapy in a randomized trial by Rasmussen, Thomas A, Jensen, Danny, Tolstrup, Martin, Nielsen, Ulla S, Erlandsen, Erland J, Birn, Henrik, Østergaard, Lars, Langdahl, Bente L, Laursen, Alex L

“…Our objective was to compare the bone and renal effects among HIV-infected patients randomized to abacavir or tenofovir-based combination anti-retroviral…”
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"Development in well-being and social function among Danish hemophilia patients with HIV: a three-wave panel study spanning 24 years" by Ingvorsen, Emilie B, Schnohr, Christina, Andersen, Terkel, Lehrmann, Lars, Funding, Eva, Poulsen, Lone H, Holm, Karen B, Laursen, Alex L, Gerstoft, Jan, Bjorner, Jakob B

“…Between 1975 and 1985 a total of 91 Danish patients with moderate and severe hemophilia (PWH) was infected with HIV constituting a major scandal in the Danish…”
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Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system by Rasmussen, Thomas A, Tolstrup, Martin, Møller, Holger Jon, Brinkmann, Christel R, Olesen, Rikke, Erikstrup, Christian, Laursen, Alex L, Østergaard, Lars, Søgaard, Ole S

“…In a substudy of a clinical trial, we assessed whether activation of latent human immunodeficiency virus (HIV) by the histone deacetylase inhibitor…”
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Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in Denmark: identification of viral resistance mutations by Sølund, Christina, Krarup, Henrik, Ramirez, Santseharay, Thielsen, Peter, Røge, Birgit T, Lunding, Suzanne, Barfod, Toke S, Madsen, Lone G, Tarp, Britta, Christensen, Peer B, Gerstoft, Jan, Laursen, Alex L, Bukh, Jens, Weis, Nina

“…The first standard of care in treatment of chronic HCV genotype 1 infection involving directly acting antivirals was protease inhibitors telaprevir or…”
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Impact of Hepatitis C Virus Coinfection on Response to Highly Active Antiretroviral Therapy and Outcome in HIV-Infected Individuals: A Nationwide Cohort Study by Weis, Nina, Lindhardt, Bjarne Ø., Kronborg, Gitte, Hansen, Ann-Brit E., Laursen, Alex L., Christensen, Peer B., Nielsen, Henrik, Møller, Axel, Sørensen, Henrik T., Obel, Niels

“…Background. Coinfection with hepatitis C virus (HCV) in human immunodeficiency virus (HIV) type 1—infected patients may decrease the effectiveness of highly…”
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Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy by Rasmussen, Thomas A, Tolstrup, Martin, Melchjorsen, Jesper, Frederiksen, Christian A, Nielsen, Ulla S, Langdahl, Bente L, Østergaard, Lars, Laursen, Alex L

“…Our objective was to evaluate and compare the effect of abacavir on levels of biomarkers associated with cardiovascular risk. In an open-label randomized…”
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Effectiveness of treatment with pegylated interferon and ribavirin in an unselected population of patients with chronic hepatitis C: a Danish nationwide cohort study by Hansen, Nanna, Obel, Niels, Christensen, Peer B, Kjær, Mette, Laursen, Alex L, Krarup, Henrik B, Møller, Axel, Schlichting, Poul, Bukh, Jens, Weis, Nina

“…The effect of peginterferon and ribavirin treatment on chronic hepatitis C virus (HCV) infection has been established in several controlled clinical studies…”
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Monocyte phenotype and extracellular vesicles in HIV-1, HIV-2, and HIV-1/2 dual infection by Hønge, Bo L., Andersen, Morten N, Petersen, Mikkel S., Jespersen, Sanne, Medina, Candida, Té, David DS, Kjerulff, Bertram, Laursen, Alex L., Møller, Holger J., Wejse, Christian, Krarup, Henrik, Møller, Bjarne K., Erikstrup, Christian

“…AIDS-defining illness develops at higher CD4+ T-cell counts in individuals infected with HIV-2 compared with HIV-1 infected, which suggests that the two types…”
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Entecavir Therapy Induces de Novo HIV Reverse-Transcriptase M184V Mutation in an Antiretroviral Therapy—Naive Patient by Jakobsen, Martin R., Arildsen, Hanne, Krarup, Henrik B., Tolstrup, Martin, Østergaard, Lars, Laursen, Alex L.

“…Recently, entecavir was introduced as a potent drug against hepatitis B virus infection. Initially, it was suggested not to have any effect on human…”
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Global evolutionary analysis of chronic hepatitis C patients revealed significant effect of baseline viral resistance, including novel non‐target sites, for DAA‐based treatment and retreatment outcome by Fahnøe, Ulrik, Pedersen, Martin S., Sølund, Christina, Ernst, Anja, Krarup, Henrik B., Røge, Birgit T., Christensen, Peer B., Laursen, Alex L., Gerstoft, Jan, Thielsen, Peter, Madsen, Lone G., Pedersen, Anders G., Schønning, Kristian, Weis, Nina, Bukh, Jens

“…Direct‐acting antivirals (DAAs) have proven highly effective against chronic hepatitis C virus (HCV) infection. However, some patients experience treatment…”
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Grazoprevir, ruzasvir, and uprifosbuvir for hepatitis C virus after NS5A treatment failure by Wyles, David, Wedemeyer, Heiner, Ben‐Ari, Ziv, Gane, Edward J., Hansen, Jesper Bach, Jacobson, Ira M., Laursen, Alex L., Luetkemeyer, Annie, Nahass, Ronald, Pianko, Stephen, Zeuzem, Stefan, Jumes, Patricia, Huang, Hsueh‐Cheng, Butterton, Joan, Robertson, Michael, Wahl, Janice, Barr, Eliav, Joeng, Hee‐Koung, Martin, Elizabeth, Serfaty, Lawrence

“…People with hepatitis C virus (HCV) infection who have failed treatment with an all‐oral regimen represent a challenging treatment population. The present…”
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T-cell and B-cell perturbations identify distinct differences in HIV-2 compared with HIV-1-induced immunodeficiency by Hønge, Bo L, Petersen, Mikkel S, Jespersen, Sanne, Medina, Candida, Té, David D.S, Kjerulff, Bertram, Engell-Sørensen, Thomas, Madsen, Tina, Laursen, Alex L, Wejse, Christian, Krarup, Henrik, Møller, Bjarne K, Erikstrup, Christian

“…BACKGROUND:For unknown reasons, HIV-2 is less pathogenic than HIV-1, and HIV-2-induced immunodeficiency may be different from that caused by HIV-1. Previous…”
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Direct acting antiviral treatment of chronic hepatitis C in Denmark: factors associated with and barriers to treatment initiation by Sølund, Christina, Hallager, Sofie, Pedersen, Martin S., Fahnøe, Ulrik, Ernst, Anja, Krarup, Henrik B., Røge, Birgit T., Christensen, Peer B., Laursen, Alex L., Gerstoft, Jan, Bélard, Erika, Madsen, Lone G., Schønning, Kristian, Pedersen, Anders G., Bukh, Jens, Weis, Nina

“…Objectives: We describe factors associated with and barriers to initiation of Direct Acting Antiviral (DAA) treatment in patients with chronic hepatitis C, who…”
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T-cell and B-cell perturbations are similar in ART-naive HIV-1 and HIV-1/2 dually infected patients by Hønge, Bo L, Petersen, Mikkel S, Jespersen, Sanne, Medina, Candida, Té, David D.S, Kjerulff, Bertram, Jensen, Mads M, Steiniche, Ditte, Esbjörnsson, Joakim, Laursen, Alex L, Wejse, Christian, Krarup, Henrik, Møller, Bjarne K, Erikstrup, Christian

“…BACKGROUND:HIV-2 may slow progression of a subsequently acquired HIV-1 infection through cross-neutralizing antibodies and polyfunctional CD8 T cells. We…”
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Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: a clinical randomized study by Sølund, Christina, Andersen, Ellen S, Mössner, Belinda, Laursen, Alex L, Røge, Birgit T, Kjær, Mette S, Gerstoft, Jan, Christensen, Peer B, Pedersen, Martin S, Schønning, Kristian, Fahnøe, Ulrik, Bukh, Jens, Weis, Nina

“…OBJECTIVENew potent direct-acting antiviral (DAA) regimens against hepatitis C virus have been approved in recent years. However, information about the rate of…”
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Acceptance and Feasibility of Partner Notification to HIV Infected Individuals in Guinea-Bissau by Madsen, Tina, Jespersen, Sanne, Medina, Candida, Té, David D. S., Wejse, Christian, Laursen, Alex L., Hønge, Bo L.

“…As partner notification (PN) has shown effective in increasing the number of partners of HIV infected patients being tested we aimed to evaluate the…”
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Interobserver Variation of the Rapid Test SD Bioline HIV-1/2 3.0 for HIV Type Discrimination: Experiences From Guinea-Bissau by Hønge, Bo Langhoff, Jespersen, Sanne, Bjarnason Obinah, Magnús P, Medina, Candida, da Silva Té, David, da Silva, Zacarias J, Østergaard, Lars, Laursen, Alex L, Erikstrup, Christian, Wejse, Christian

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Incidence of Hepatocellular Carcinoma and Decompensated Liver Cirrhosis and Prognostic Accuracy of the PAGE-B HCC Risk Score in a Low Endemic Hepatitis B Virus Infected Population by Bollerup, Signe, Engsig, Frederik, Hallager, Sofie, Mocroft, Amanda, Roege, Birgit T, Christensen, Peer B, Laursen, Alex L, Krarup, Henrik, Clausen, Mette R, Thielsen, Peter, Madsen, Lone G, Noerregaard, Lars, Barfod, Toke S, Balslev, Ulla, Tarp, Britta, Hansen, Jesper B, Mygind, Lone H, Gerstoft, Jan, Weis, Nina

“…Purpose: We aimed to determine incidence of hepatocellular carcinoma (HCC) and decompensated liver cirrhosis in persons with chronic hepatitis B virus (HBV)…”
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Epidemic Stevens-Johnson syndrome in HIV patients in Guinea-Bissau: a side effect of the drug-supply policy? by OLIVEIRA, Inés, JENSEN-FANGEL, Soren, SODEMANN, Morten, LAURSEN, Alex L, DA SILVA, David, NDUMBA, Agostinho, MEDINA, Candida, NANADJE, Albino, RASMUSSEN, Dlama N, RUDOLF, Frauke, WEJSE, Christian, DA SILVA, Zacarias J

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