Search Results - "Lauron, Elvin J."

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms by Tortorici, M Alejandra, Beltramello, Martina, Lempp, Florian A, Pinto, Dora, Dang, Ha V, Rosen, Laura E, McCallum, Matthew, Bowen, John, Minola, Andrea, Jaconi, Stefano, Zatta, Fabrizia, De Marco, Anna, Guarino, Barbara, Bianchi, Siro, Lauron, Elvin J, Tucker, Heather, Zhou, Jiayi, Peter, Alessia, Havenar-Daughton, Colin, Wojcechowskyj, Jason A, Case, James Brett, Chen, Rita E, Kaiser, Hannah, Montiel-Ruiz, Martin, Meury, Marcel, Czudnochowski, Nadine, Spreafico, Roberto, Dillen, Josh, Ng, Cindy, Sprugasci, Nicole, Culap, Katja, Benigni, Fabio, Abdelnabi, Rana, Foo, Shi-Yan Caroline, Schmid, Michael A, Cameroni, Elisabetta, Riva, Agostino, Gabrieli, Arianna, Galli, Massimo, Pizzuto, Matteo S, Neyts, Johan, Diamond, Michael S, Virgin, Herbert W, Snell, Gyorgy, Corti, Davide, Fink, Katja, Veesler, David

“…Efficient therapeutic options are needed to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has caused more than…”
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WDFY4 is required for cross-presentation in response to viral and tumor antigens by Theisen, Derek J, Davidson, 4th, Jesse T, Briseño, Carlos G, Gargaro, Marco, Lauron, Elvin J, Wang, Qiuling, Desai, Pritesh, Durai, Vivek, Bagadia, Prachi, Brickner, Joshua R, Beatty, Wandy L, Virgin, Herbert W, Gillanders, William E, Mosammaparast, Nima, Diamond, Michael S, Sibley, L David, Yokoyama, Wayne, Schreiber, Robert D, Murphy, Theresa L, Murphy, Kenneth M

“…During the process of cross-presentation, viral or tumor-derived antigens are presented to CD8 T cells by dependent CD8α /XCR1 classical dendritic cells…”
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Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9 by Stephens, Calvin J., Lauron, Elvin J., Kashentseva, Elena, Lu, Zhi Hong, Yokoyama, Wayne M., Curiel, David T.

“…Hemophilia B (HB) is a life-threatening inherited disease caused by mutations in the FIX gene, leading to reduced protein function and abnormal blood clotting…”
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Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii by Behnke, Michael S, Khan, Asis, Lauron, Elvin J, Jimah, John R, Wang, Qiuling, Tolia, Niraj H, Sibley, L David

“…Toxoplasma gondii has evolved a number of strategies to evade immune responses in its many hosts. Previous genetic mapping of crosses between clonal type 1, 2,…”
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HIF1α is required for NK cell metabolic adaptation during virus infection by Victorino, Francisco, Bigley, Tarin M, Park, Eugene, Yao, Cong-Hui, Benoit, Jeanne, Yang, Li-Ping, Piersma, Sytse J, Lauron, Elvin J, Davidson, Rebecca M, Patti, Gary J, Yokoyama, Wayne M

“…Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we…”
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Human Cytomegalovirus Infection of Langerhans-Type Dendritic Cells Does Not Require the Presence of the gH/gL/UL128-131A Complex and Is Blocked after Nuclear Deposition of Viral Genomes in Immature Cells by Lauron, Elvin J, Yu, Dong, Fehr, Anthony R, Hertel, Laura

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cross-priming induces immunodomination in the presence of viral MHC class I inhibition by Lauron, Elvin J, Yang, Liping, Elliott, Jabari I, Gainey, Maria D, Fremont, Daved H, Yokoyama, Wayne M

“…Viruses have evolved mechanisms of MHCI inhibition in order to evade recognition by cytotoxic CD8+ T cells (CTLs), which is well-illustrated by our prior…”
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Transcriptome sequencing and analysis of Plasmodium gallinaceum reveals polymorphisms and selection on the apical membrane antigen-1 by Lauron, Elvin J, Oakgrove, Khouanchy S, Tell, Lisa A, Biskar, Kevin, Roy, Scott W, Sehgal, Ravinder N M

“…Plasmodium erythrocyte invasion genes play a key role in malaria parasite transmission, host-specificity and immuno-evasion. However, the evolution of the…”
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A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion by Patel, Swapneel J, Zhao, Guoyan, Penna, Vinay R, Park, Eugene, Lauron, Elvin J, Harvey, Ian B, Beatty, Wandy L, Plougastel-Douglas, Beatrice, Poursine-Laurent, Jennifer, Fremont, Daved H, Wang, David, Yokoyama, Wayne M

“…The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the genus of the human subfamily. Infections with these viruses have been…”
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Viral MHCI inhibition evades tissue-resident memory T cell formation and responses by Lauron, Elvin J, Yang, Liping, Harvey, Ian B, Sojka, Dorothy K, Williams, Graham D, Paley, Michael A, Bern, Michael D, Park, Eugene, Victorino, Francisco, Boon, Adrianus C M, Yokoyama, Wayne M

“…Tissue-resident memory CD8 T cells (T s) confer rapid protection and immunity against viral infections. Many viruses have evolved mechanisms to inhibit MHCI…”
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Coevolutionary patterns and diversification of avian malaria parasites in African sunbirds (Family Nectariniidae) by Lauron, Elvin J, Loiseau, Claire, Bowie, Rauri C K, Spicer, Greg S, Smith, Thomas B, Melo, Martim, Sehgal, Ravinder N M

“…The coevolutionary relationships between avian malaria parasites and their hosts influence the host specificity, geographical distribution and pathogenicity of…”
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279 Preclinical evaluation of allogeneic CD19 CAR T cells expressing an anti-rejection CD70 CAR by Lauron, Elvin J, Zhang, Kristen, Sanchez, Jerick, Ramanathan, Vidhya, Nguyen, Duy, Nguyen, George, Sasu, Barbra, Sommer, Cesar

“…BackgroundAutologous CAR T cell therapies have revolutionized the treatment of hematologic malignancies but have inherent disadvantages that hinder widespread…”
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CD8 + T cell targeting of tumor antigens presented by HLA-E by Iyer, Ravi F, Verweij, Marieke C, Nair, Sujit S, Morrow, David, Mansouri, Mandana, Chakravarty, Dimple, Beechwood, Teresa, Meyer, Christine, Uebelhoer, Luke, Lauron, Elvin J, Selseth, Andrea, John, Nessy, Thin, Tin Htwe, Dzedzik, Siarhei, Havenar-Daughton, Colin, Axthelm, Michael K, Douglas, Janet, Korman, Alan, Bhardwaj, Nina, Tewari, Ashutosh K, Hansen, Scott, Malouli, Daniel, Picker, Louis J, Früh, Klaus

“…The nonpolymorphic major histocompatibility complex E (MHC-E) molecule is up-regulated on many cancer cells, thus contributing to immune evasion by engaging…”
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De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification by Lauron, Elvin J, Aw Yeang, Han Xian, Taffner, Samantha M, Sehgal, Ravinder N M

“…Malaria parasites that infect birds can have narrow or broad host-tropisms. These differences in host specificity make avian malaria a useful model for…”
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Glycosylation modulates arenavirus glycoprotein expression and function by Bonhomme, Cyrille J, Capul, Althea A, Lauron, Elvin J, Bederka, Lydia H, Knopp, Kristeene A, Buchmeier, Michael J

“…Abstract The glycoprotein of lymphocytic choriomeningitis virus (LCMV) contains nine potential N-linked glycosylation sites. We investigated the function of…”
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Cellular Mechanisms Affecting Allogeneic CAR T Cell Expansion and Rejection in Large B-Cell Lymphoma by Jallouk, Andrew P, Ge, Zhongqi, Kaimal, Vivek, Furmanak, Tom, Sommer, Cesar, Lauron, Elvin J, Sasu, Barbra J., Neelapu, Sattva S., Bachireddy, Pavan

“…Allogeneic chimeric antigen receptor (CAR) T cell therapies hold promise to improve CAR T access. However, limited expansion and persistence due to rejection…”
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Harnessing the unique immune biology of cytomegalovirus for cancer immunotherapy by Iyer, L. Ravi F, Verweij, Marieke C, Nair, Sujit, Morrow, David, Mansouri, Mandana, Beechwood, Teresa, Meyer, Christine, Chakravarty, Dimple, Uebelhoer, Luke, Ventura, Abigail, Lauron, Elvin J, Selseth, Andrea, Axthelm, Michael, Lind, Evan F, Saultz, Jennifer, Douglas, Janet, Korman, Alan, Bhardwaj, Nina, Tewari, Ashutosh K, Hansen, Scott G., Malouli, Daniel, Picker, Louis J, Fruh, Klaus

“…Abstract Pre-clinical models in non-human primates demonstrate that cytomegalovirus (CMV)-vectored vaccines are unique in their ability to elicit and…”
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Wdfy4 -deficiency reveals a critical role for cross-presentation in anti-viral and anti-tumor responses by Theisen, Derek J, Davidson, Jesse T, Briseño, Carlos G, Gargaro, Marco, Lauron, Elvin J, Wang, Qiuling, Desai, Pritesh, Durai, Vivek, Bagadia, Prachi, Brickner, Joshua R, Beatty, Wandy L, Virgin, Herbert W, Gillanders, William E, Mossamaparast, Nima, Diamond, Michael S, Sibley, L David, Yokoyama, Wayne, Schreiber, Robert D, Murphy, Theresa L, Murphy, Kenneth M

“…Abstract Cross-presentation allows for the presentation of exogenous viral and tumor antigens to CD8+ T cells by XCR1+ classical dendritic cells (cDC1s)…”
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Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii: e1005434 by Behnke, Michael S, Khan, Asis, Lauron, Elvin J, Jimah, John R, Wang, Qiuling, Tolia, Niraj H, Sibley, L David

“…Toxoplasma gondii has evolved a number of strategies to evade immune responses in its many hosts. Previous genetic mapping of crosses between clonal type 1, 2,…”
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Viral MHC Class I Evasion Affects Anti-viral T Cell Development and Responses by Lauron, Elvin J

“…Cytotoxic CD8+ T cells (CTLs) play a critical role in protective immunity against viruses, a fact underscored by the evolution of viral CTL evasion mechanisms…”
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