Search Results - "Lauritsen, Johanne"
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Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells
Published in Nature communications (05-12-2023)“…Current differentiation protocols for generating mesencephalic dopaminergic (mesDA) neurons from human pluripotent stem cells result in grafts containing only…”
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Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers
Published in NPJ Parkinson's Disease (29-07-2024)“…α-Synuclein (α-syn) accumulates as insoluble amyloid but also forms soluble α-syn oligomers (αSOs), thought to be even more cytotoxic than fibrils. To detect…”
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The systemic immune response in Parkinson’s disease: focus on the peripheral immune component
Published in Trends in neurosciences (Regular ed.) (01-10-2023)“…Genetic studies support a role for the immune system in Parkinson’s disease (PD), with particular significance for microglia and monocytes.Proteins related to…”
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Neuroinflammation and Immune Changes in Prodromal Parkinson's Disease and Other Synucleinopathies
Published in Journal of Parkinson's disease (01-01-2022)“…Multiple lines of clinical and pre-clinical research support a pathogenic role for neuroinflammation and peripheral immune system dysfunction in Parkinson's…”
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