Search Results - "Laurindo, Francisco R"

Time-dependent effects of training on cardiovascular control in spontaneously hypertensive rats: role for brain oxidative stress and inflammation and baroreflex sensitivity by Masson, Gustavo S, Costa, Tassia S R, Yshii, Lidia, Fernandes, Denise C, Soares, Pedro Paulo Silva, Laurindo, Francisco R, Scavone, Cristoforo, Michelini, Lisete C

“…Baroreflex dysfunction, oxidative stress and inflammation, important hallmarks of hypertension, are attenuated by exercise training. In this study, we…”
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Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis by Kowaltowski, Alicia J., Menezes‐Filho, Sergio L., Assali, Essam A., Gonçalves, Isabela G., Cabral‐Costa, João Victor, Abreu, Phablo, Miller, Nathanael, Nolasco, Patricia, Laurindo, Francisco R. M., Bruni‐Cardoso, Alexandre, Shirihai, Orian S.

“…Changes in mitochondrial size and shape have been implicated in several physiologic processes, but their role in mitochondrial Ca2+ uptake regulation and…”
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Mild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis by Cerqueira, Fernanda M, Laurindo, Francisco R M, Kowaltowski, Alicia J

“…Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR). Since…”
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Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene by Kajihara, Daniela, Hon, Chung-Chau, Abdullah, Aimi Naim, Wosniak, Jr, João, Moretti, Ana Iochabel S, Poloni, Joice F, Bonatto, Diego, Hashimoto, Kosuke, Carninci, Piero, Laurindo, Francisco R M

“…Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis,…”
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Blood meal-derived heme decreases ROS levels in the midgut of Aedes aegypti and allows proliferation of intestinal microbiota by Oliveira, Jose Henrique M, Gonçalves, Renata L S, Lara, Flavio A, Dias, Felipe A, Gandara, Ana Caroline P, Menna-Barreto, Rubem F S, Edwards, Meredith C, Laurindo, Francisco R M, Silva-Neto, Mário A C, Sorgine, Marcos H F, Oliveira, Pedro L

“…The presence of bacteria in the midgut of mosquitoes antagonizes infectious agents, such as Dengue and Plasmodium, acting as a negative factor in the vectorial…”
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Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension by Salibe-Filho, William, Araujo, Thaís L S, G Melo, Everton, B C T Coimbra, Luiza, Lapa, Monica S, Acencio, Milena M P, Freitas-Filho, Orival, Capelozzi, Vera Luiza, Teixeira, Lisete Ribeiro, Fernandes, Caio J C S, Jatene, Fabio Biscegli, Laurindo, Francisco R M, Terra-Filho, Mario

“…The pathophysiological mechanisms underlying chronic thromboembolic pulmonary hypertension (CTEPH) are still unclear. Endothelial cell (EC) remodeling is…”
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Redox modulation of FAK controls melanoma survival--role of NOX4 by Ribeiro-Pereira, Cristiane, Moraes, João Alfredo, Souza, Mariele de Jesus, Laurindo, Francisco R, Arruda, Maria Augusta, Barja-Fidalgo, Christina

“…Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the…”
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Testosterone Induces Vascular Smooth Muscle Cell Migration by NADPH Oxidase and c-Src–Dependent Pathways by Chignalia, Andreia Z, Schuldt, Elke Z, Camargo, Lívia L, Montezano, Augusto C, Callera, Gláucia E, Laurindo, Francisco R, Lopes, Lucia R, Avellar, Maria Christina W, Carvalho, Maria Helena C, Fortes, Zuleica B, Touyz, Rhian M, Tostes, Rita C

“…Testosterone has been implicated in vascular remodeling associated with hypertension. Molecular mechanisms underlying this are elusive, but oxidative stress…”
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A red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition by Haas, Elisa A, Saad, Mario JA, Santos, Andrey, Vitulo, Nicola, Lemos, Jr, Wilson JF, Martins, Aline MA, Picossi, Carolina RC, Favarato, Desidério, Gaspar, Renato S, Magro, Daniéla O, Libby, Peter, Laurindo, Francisco RM, Da Luz, Protasio L

“…Gut microbiota profiles are closely related to cardiovascular diseases through mechanisms that include the reported deleterious effects of metabolites, such as…”
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Protein disulfide isomerase redox-dependent association with p47phox: evidence for an organizer role in leukocyte NADPH oxidase activation by de A. Paes, Antonio Marcus, Veríssimo-Filho, Sidney, Guimarães, Luciana Lopes, Silva, Ana Carolina B, Takiuti, Júlia T, Santos, Célio X C, Janiszewski, Mariano, Laurindo, Francisco R M, Lopes, Lucia R

“…Leukocyte NADPH oxidase activity is regulated by associated protein disulfide isomerase via redox mechanisms involving p47phox. Mechanisms of leukocyte NADPH…”
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Oxidant Generation Predominates Around Calcifying Foci and Enhances Progression of Aortic Valve Calcification by Liberman, Marcel, Bassi, Estêvão, Martinatti, Marina Kamla, Lario, Fábio Cerqueira, Wosniak, João, Pomerantzeff, Pablo M.A, Laurindo, Francisco R.M

“…OBJECTIVE—We hypothesized that reactive oxygen species (ROS) contribute to progression of aortic valve (AV) calcification/stenosis. METHODS AND RESULTS—We…”
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Analysis of DHE-derived oxidation products by HPLC in the assessment of superoxide production and NADPH oxidase activity in vascular systems by Fernandes, Denise C, Wosniak, Jr, João, Pescatore, Luciana A, Bertoline, Maria A, Liberman, Marcel, Laurindo, Francisco R M, Santos, Célio X C

“…Dihydroethidium (DHE) is a widely used sensitive superoxide (O2(*-)) probe. However, DHE oxidation yields at least two fluorescent products, 2-hydroxyethidium…”
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Effects of High Adherence to Mediterranean or Low-Fat Diets in Medicated Secondary Prevention Patients by Thomazella, Maria Cristina D., PhD, Góes, Marisa F.S., RN, Andrade, Cláudia R., PhD, Debbas, Victor, MSc, Barbeiro, Denise F., PhD, Correia, Renata L., PhD, Marie, Sueli K.N., MD, PhD, Cardounel, Arturo J., PhD, daLuz, Protásio L., MD, PhD, Laurindo, Francisco R.M., MD, PhD

“…Although the Mediterranean diet (MD) and the low-fat Therapeutic Lifestyle Changes Diet (TLCD) promote equivalent increases in event-free survival in secondary…”
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Proteasome inhibition represses unfolded protein response and Nox4, sensitizing vascular cells to endoplasmic reticulum stress-induced death by Amanso, Angélica M, Debbas, Victor, Laurindo, Francisco R M

“…Endoplasmic reticulum (ER) stress has pathophysiological relevance in vascular diseases and merges with proteasome function. Proteasome inhibition induces cell…”
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Cell-surface HSP70 associates with thrombomodulin in endothelial cells by Araujo, Thaís L. S., Venturin, Gabriela, Moretti, Ana I. S., Tanaka, Leonardo Y., Pereira, Alexandre Costa, Laurindo, Francisco R. M.

“…Heat shock protein-70 (HSP70) is crucial for proteostasis and displays cell-protective effects. Meanwhile, enhanced levels of cell-surface (cs) and secreted…”
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Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204 by Tanaka, Leonardo Y, Kumar, Sandeep, Gutierre, Lucas F, Magnun, Celso, Kajihara, Daniela, Kang, Dong-Won, Laurindo, Francisco R M, Jo, Hanjoong

“…Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during…”
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Antioxidant Activity of Uruguayan Propolis. In Vitro and Cellular Assays by Silva, Verónica, Genta, Gonzalo, Möller, Matías N, Masner, Martín, Thomson, Leonor, Romero, Natalia, Radi, Rafael, Fernandes, Denise C, Laurindo, Francisco R. M, Heinzen, Horacio, Fierro, Walter, Denicola, Ana

“…The antioxidant capacity of propolis from the southern region of Uruguay was evaluated using in vitro as well as cellular assays. Free radical scavenging…”
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A Secreted Phospholipase A2 Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State by Giannotti, Karina Cristina, Weinert, Sönke, Viana, Mariana Nascimento, Leiguez, Elbio, Araujo, Thaís L. S., Laurindo, Francisco R. M., Lomonte, Bruno, Braun-Dullaeus, Rüdiger, Teixeira, Catarina

“…Vascular smooth muscle cells (VSMCs) loaded with lipid droplets (LDs) are markers of atherosclerosis. In this disease, inflammatory Group IIA-secreted…”
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An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies by Ceravolo, Graziela S, Montezano, Augusto C, Jordão, Maria T, Akamine, Eliana H, Costa, Tiago J, Takano, Ana P, Fernandes, Denise C, Barreto-Chaves, Maria L, Laurindo, Francisco R, Tostes, Rita C, Fortes, Zuleica B, Chopard, Renato P, Touyz, Rhian M, Carvalho, Maria Helena C

“…The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R)…”
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Aerobic Exercise During Advance Stage of Uncontrolled Arterial Hypertension by Pagan, Luana U, Gomes, Mariana J, Damatto, Ricardo L, Lima, Aline R R, Cezar, Marcelo D M, Damatto, Felipe C, Reyes, David R A, Campos, Dijon H S, Caldonazo, Tulio M M, Polegato, Bertha F, Fernandes, Denise C, Laurindo, Francisco R, Fernandes, Ana A H, Lloret, Ana, Cicogna, Antonio C, Okoshi, Marina P, Okoshi, Katashi

“…To evaluate the influence of physical training on myocardial function, oxidative stress, energy metabolism, and MAPKs and NF-κB signaling pathways in…”
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