Search Results - "Laurie, Sonia J."

Type II innate lymphoid cell plasticity contributes to impaired reconstitution after allogeneic hematopoietic stem cell transplantation by Laurie, Sonia J., Foster, Joseph P., Bruce, Danny W., Bommiasamy, Hemamalini, Kolupaev, Oleg V., Yazdimamaghani, Mostafa, Pattenden, Samantha G., Chao, Nelson J., Sarantopoulos, Stefanie, Parker, Joel S., Davis, Ian J., Serody, Jonathan S.

“…Type II innate lymphoid cells (ILC2s) maintain homeostasis and barrier integrity in mucosal tissues. In both mice and humans, ILC2s poorly reconstitute after…”
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STING agonist promotes CAR T cell trafficking and persistence in breast cancer by Xu, Nuo, Palmer, Douglas C, Robeson, Alexander C, Shou, Peishun, Bommiasamy, Hemamalini, Laurie, Sonia J, Willis, Caryn, Dotti, Gianpietro, Vincent, Benjamin G, Restifo, Nicholas P, Serody, Jonathan S

“…CAR T therapy targeting solid tumors is restrained by limited infiltration and persistence of those cells in the tumor microenvironment (TME). Here, we…”
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Tumor microenvironment immunomodulation by nanoformulated TLR 7/8 agonist and PI3k delta inhibitor enhances therapeutic benefits of radiotherapy by Yazdimamaghani, Mostafa, Kolupaev, Oleg V., Lim, Chaemin, Hwang, Duhyeong, Laurie, Sonia J., Perou, Charles M., Kabanov, Alexander V., Serody, Jonathan S.

“…Infiltration of immunosuppressive cells into the breast tumor microenvironment (TME) is associated with suppressed effector T cell (Teff) responses,…”
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Corrigendum to “Tumor microenvironment immunomodulation by nanoformulated TLR 7/8 agonist and PI3k delta inhibitor enhances therapeutic benefits of radiotherapy” [Biomaterials 312 (2025) 122750 by Yazdimamaghani, Mostafa, Kolupaev, Oleg V., Lim, Chaemin, Hwang, Duhyeong, Laurie, Sonia J., Perou, Charles M., Kabanov, Alexander V., Serody, Jonathan S.

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TIGIT agonism alleviates costimulation blockade-resistant rejection in a regulatory T cell–dependent manner by Hartigan, Christina R., Tong, Katherine P., Liu, Danya, Laurie, Sonia J., Ford, Mandy L.

“…Belatacept-based immunosuppression in kidney transplantation confers fewer off-target toxicities than calcineurin inhibitors but comes at a cost of increased…”
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Efficacy of a Dual-Epitope Dendritic Cell Vaccine as Part of Combined Immunotherapy for HER2-Expressing Breast Tumors by Vincent, Benjamin G, File, Danielle M, McKinnon, Karen P, Moore, Dominic T, Frelinger, Jeffrey A, Collins, Edward J, Ibrahim, Joseph G, Bixby, Lisa, Reisdorf, Shannon, Laurie, Sonia J, Park, Yara A, Anders, Carey K, Collichio, Frances A, Muss, Hyman B, Carey, Lisa A, van Deventer, Hendrik W, Dees, E Claire, Serody, Jonathan S

“…Previous work from our group and others has shown that patients with breast cancer can generate a T cell response against specific human epidermal growth…”
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Epigenetic Remodeling in Exhausted T Cells: Implications for Transplantation Tolerance by Laurie, Sonia J, Ford, Mandy L

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2B4 Mediates Inhibition of CD8 + T Cell Responses via Attenuation of Glycolysis and Cell Division by Laurie, Sonia J, Liu, Danya, Wagener, Maylene E, Stark, Phoebe C, Terhorst, Cox, Ford, Mandy L

“…We recently showed that 2B4 expression on memory T cells in human renal transplant recipients was associated with reduced rates of rejection. To investigate…”
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Third-party type 2 innate lymphoid cells prevent and treat GI tract GvHD by Bruce, Danny W., Kolupaev, Oleg, Laurie, Sonia J., Bommiasamy, Hemamalini, Stefanski, Heather, Blazar, Bruce R., Coghill, James M., Serody, Jonathan S.

“…Acute graft-versus-host disease (aGVHD), mediated by the recognition of host major histocompatibility complex/peptide polymorphisms by donor T cells, remains a…”
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Transplantation preferentially induces a KLRG-1lo CD127hi differentiation program in antigen-specific CD8+ T cells by Bozeman, Alana M., Laurie, Sonia J., Haridas, Divya, Wagener, Maylene E., Ford, Mandy L.

“…Models of infection have shaped our understanding of programmed memory T cell differentiation, yet whether these models apply to memory programming in the…”
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Increased attrition of memory T cells during sepsis requires 2B4 by Xie, Jianfeng, Chen, Ching-Wen, Sun, Yini, Laurie, Sonia J, Zhang, Wenxiao, Otani, Shunsuke, Martin, Gregory S, Coopersmith, Craig M, Ford, Mandy L

“…Recent seminal studies have revealed that laboratory mice differ from adult humans with regard to the frequency, number, and distribution of memory T cells…”
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Rat Chromosome 8 Confers Protection against Dyslipidemia Caused by a High-Fat/ Low-Carbohydrate Diet by Solberg Woods, Leah C., Woods, Brett C., Leitschuh, Caroline M., Laurie, Sonia J., Jacob, Howard J.

“…Background/Aims: Recent studies have highlighted the importance of gene by diet interactions in contributing to risk factors of metabolic syndrome. We used a…”
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Amphiregulin Derived from Multiple Sources Is Important for Barrier Function of the Intestine Following Hematopoietic Stem Cell Transplantation by Bruce, Danny W., Kolupaev, Oleg, Laurie, Sonia J., Bommiasamy, Hemamalini, Serody, Jonathan S.

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Cytotoxic Therapy Impairs the Stromal Niche Supporting ILC Development in the Bone Marrow by Kolupaev, Oleg, Bruce, Danny W., Laurie, Sonia J., Bommiasamy, Hemamalini, Serody, Jonathan S.

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TIGIT agonism alleviates costimulation blockade resistant rejection in a Treg-dependent manner by Hartigan, Christina R., Tong, Katherine P., Liu, Danya, Laurie, Sonia J., Ford, Mandy L.

“…Belatacept-based immunosuppression in kidney transplantation confers fewer off-target toxicities compared to calcineurin inhibitors but comes at a cost of…”
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Absence of ILC2 Recovery Post-Transplant Is Mediated By Epigenetic Conversion of ILC2 to Pro-Inflammatory ILC1-like Cells by Laurie, Sonia J., Foster, Joseph P., Bruce, Danny W., Bommiasamy, Hemamalini, Pattenden, Samantha G., Davis, Ian J., Serody, Jonathan S.

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Epigenetic Plasticity of Type II Innate Lymphoid Cells in the Lower Gastrointestinal Tract by Laurie, Sonia J., Bruce, Danny W., Bommiasamy, Hemamalini, Noel, Melodie P, Foster, Joseph P., Davis, Ian J., Pattenden, Samantha G., Serody, Jonathan S

“…Though hematopoietic stem cell transplantation (HSCT) is the preferred treatment for a variety of blood malignancies, its use is limited by the development of…”
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Increased Pre-Transplant Frequency of CD28+ CD4+ TEM Predicts Belatacept-Resistant Rejection in Human Renal Transplant Recipients by Cortes-Cerisuelo, Miriam, Laurie, Sonia J., Mathews, David V., Winterberg, Pamela D., Larsen, Christian P., Adams, Andrew B., Ford, Mandy L.

“…While most human T cells express the CD28 costimulatory molecule constitutively, it is well-known that age, inflammation, and viral infection can drive the…”
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Transplantation preferentially induces a KLRG-1 lo CD127 hi differentiation program in antigen-specific CD8 + T cells by Bozeman, Alana M, Laurie, Sonia J, Haridas, Divya, Wagener, Maylene E, Ford, Mandy L

“…Models of infection have shaped our understanding of programmed memory T cell differentiation, yet whether these models apply to memory programming in the…”
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